Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yange, Cui"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Ferroptosis is an iron-dependent, lipid peroxidation-driven cell death pathway, while Parkinson’s disease (PD) patients exhibit iron deposition and lipid peroxidation in the brain. Thus, the features of ferroptosis highly overlap with the
Externí odkaz:
https://doaj.org/article/517b7799e05d4719bf290ad28f726af7
Autor:
Yange Cui, Luyang Wang, Qingbao Ding, Jihae Shin, Joel Cassel, Qin Liu, Joseph M. Salvino, Bin Tian
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Cleavage and polyadenylation (CPA) is responsible for 3′ end processing of eukaryotic poly(A)+ RNAs and preludes transcriptional termination. JTE-607, which targets CPSF-73, is the first known CPA inhibitor (CPAi) in mammalian cells. Here
Externí odkaz:
https://doaj.org/article/e9b3e1159ab1464199de78e8383a1b46
Autor:
Guojun Hou, Tian Zhou, Ning Xu, Zhihua Yin, Xinyi Zhu, Yutong Zhang, Yange Cui, Jianyang Ma, Yuanjia Tang, Zhaorui Cheng, Yiwei Shen, Yashuo Chen, Ling‐Hua Zou, Yong‐fei Wang, Zihang Yin, Ya Guo, Huihua Ding, Zhizhong Ye, Nan Shen
Publikováno v:
Arthritis & Rheumatology. 75:574-585
Autor:
Guojun, Hou, Tian, Zhou, Ning, Xu, Zhihua, Yin, Xinyi, Zhu, Yutong, Zhang, Yange, Cui, Jianyang, Ma, Yuanjia, Tang, Zhaorui, Cheng, Yiwei, Shen, Yashuo, Chen, Ling-Hua, Zou, Yong-Fei, Wang, Zihang, Yin, Ya, Guo, Huihua, Ding, Zhizhong, Ye, Nan, Shen
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
IRF5 plays a crucial role in the development of lupus. GWAS has identified several SLE risk SNPs enriched in the IRF5 locus. However, no comprehensive genome editing-based functional analysis exists to establish a direct link between these variants a
Autor:
Tong-Tong Pei, Zhuo Wang, Yange Cui, Tang M, Huacheng Luo, Yan S, Kan Y, Huaifeng Li, Tao G. Dong, Zheng H
The type VI secretion system (T6SS) is a double-tubular toxin-injection nanomachine widely found in gram-negative human and plant pathogens. The current model depicts that the T6SS spear-like Hcp tube is powered by the contraction of an outer sheath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8448b1c5e1b6eb79e3e689b8847c4a9a
https://doi.org/10.1101/2021.05.31.446370
https://doi.org/10.1101/2021.05.31.446370
Autor:
Rong, Qiu, Xiang, Yu, Li, Wang, Zhijun, Han, Chao, Yao, Yange, Cui, Guojun, Hou, Dai, Dai, Wenfei, Jin, Nan, Shen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 204(12)
It is well known that some pathogenic cells have enhanced glycolysis; the regulatory network leading to increased glycolysis are not well characterized. In this study, we show that CNS-infiltrated pathogenic T
Autor:
Qiang Guo, Xin Gao, Zhuojun Liao, Jie Qian, Yao Meng, Yange Cui, Nan Shen, Bo Qu, Huihua Ding, Yan Wang, Ya Liu, Lingling Wu, Min Dai, Jiehua Wang, Jun Deng, Chao Yao, Guojun Hou
Publikováno v:
Arthritis & Rheumatology. 70:2036-2045
Objective Increasing evidence indicates that the cyclic GMP-AMP synthase/stimulator of interferon genes (cGAS/STING) signaling pathway has a critical pathogenic role in systemic lupus erythematosus (SLE). Expression levels of the interferon (IFN)-ind
Autor:
Jiehua, Wang, Min, Dai, Yange, Cui, Guojun, Hou, Jun, Deng, Xin, Gao, Zhuojun, Liao, Ya, Liu, Yao, Meng, Lingling, Wu, Chao, Yao, Yan, Wang, Jie, Qian, Qiang, Guo, Huihua, Ding, Bo, Qu, Nan, Shen
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(12)
Increasing evidence indicates that the cyclic GMP-AMP synthase/stimulator of interferon genes (cGAS/STING) signaling pathway has a critical pathogenic role in systemic lupus erythematosus (SLE). Expression levels of the interferon (IFN)-inducible gen
Deregulation of TGF-β1 signaling induces glycolysis by chromatin remodeling in pathogenic TH17 cells
SummaryIt is well known that some pathogenic cells have enhanced glycolysis, the regulatory network leading to increased glycolysis are not well characterized. Here, we show that pathogenic TH17 cells specifically upregulate glycolytic pathway genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff6895d99ef626c702c3c1db4f33192
https://doi.org/10.1101/218545
https://doi.org/10.1101/218545
Autor:
Fang Nan, Kaige Dong, Huihua Ding, Shan Jiang, Si-Kun Guo, Xiang Li, Wei Xue, Ling-Ling Chen, Zhaocai Zhou, Li Yang, Chu-Xiao Liu, Bo Qu, Nan Shen, Xiang Gao, Yange Cui
Publikováno v:
Cell. 177:865-880.e21
Summary Circular RNAs (circRNAs) produced from back-splicing of exons of pre-mRNAs are widely expressed, but current understanding of their functions is limited. These RNAs are stable in general and are thought to have unique structural conformations