Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yang-Nim Park"'
Autor:
Deborah J. Wessels, Claude Pujol, Nikash Pradhan, Daniel F. Lusche, Luis Gonzalez, Sydney E. Kelly, Elizabeth M. Martin, Edward R. Voss, Yang-Nim Park, Michael Dailey, Sonia L. Sugg, Sneha Phadke, Amani Bashir, David R. Soll
Publikováno v:
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 224-248 (2021)
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs). We demonstrate that MB-231 canc
Externí odkaz:
https://doaj.org/article/7991f97a6dae480db99bc4ec05492b00
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Candida albicans, a pervasive opportunistic pathogen, undergoes a unique phenotypic transition from a “white” phenotype to an “opaque” phenotype. The switch to opaque impacts gene expression, cell morphology, wall structure, metaboli
Externí odkaz:
https://doaj.org/article/c6f5c95f34384faf8f16920846455add
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT The transcription factor EFG1 functions as a suppressor of white-to-opaque and white-to-gray switching in a/α strains of Candida albicans. In a collection of 27 clinical isolates, 4 of the 17 EFG1/EFG1 strains, 1 of the 2 EFG1/efg1 strains,
Externí odkaz:
https://doaj.org/article/e964f6a2b1a540c49c29e154fde26382
Publikováno v:
mSphere, Vol 4, Iss 2 (2019)
ABSTRACT Candida albicans remains the most pervasive fungal pathogen colonizing humans. The majority of isolates from hosts are heterozygous at the mating type locus (MTLa/α), and a third of these have recently been shown to be capable of switching
Externí odkaz:
https://doaj.org/article/58db01d522d64345ae0cc4e119aeeea8
Autor:
Deborah J Wessels, Nikash Pradhan, Yang-Nim Park, Megan A Klepitsch, Daniel F Lusche, Karla J Daniels, Kayla D Conway, Edward R Voss, Suchaeta V Hegde, Thomas P Conway, David R Soll
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218854 (2019)
Tumorigenic cells undergo cell aggregation and aggregate coalescence in a 3D Matrigel environment. Here, we expanded this 3D platform to assess the interactions of normal human dermal fibroblasts (NHDFs) and human primary mammary fibroblasts (HPMFs)
Externí odkaz:
https://doaj.org/article/09bea94a3ce04961ab0abb6fe31c2a55
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 6, Pp 1725-1737 (2016)
In Candida albicans the transcription factor Efg1, which is differentially expressed in the white phase of the white-opaque transition, is essential for expression of the white phenotype. It is one of six transcription factors included in a proposed
Externí odkaz:
https://doaj.org/article/f7c42f45b5d04983a1891b9f5ebb718b
Autor:
Yang-Nim Park, David Morales, Emily H Rubinson, Daniel Masison, Evan Eisenberg, Lois E Greene
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37692 (2012)
[PSI(+)] yeast, containing the misfolded amyloid conformation of Sup35 prion, is cured by inactivation of Hsp104. There has been controversy as to whether inactivation of Hsp104 by guanidine treatment or by overexpression of the dominant negative Hsp
Externí odkaz:
https://doaj.org/article/05b6062801524893bafe7b47ee4af13b
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40329 (2012)
Diffusion coefficients of huntingtin (Htt) fragments and SOD1 mutants expressed in cells were measured using fluorescence correlation spectroscopy. The diffusion mobilities of both non-pathological Htt fragments (25 polyQs) and pathological Htt fragm
Externí odkaz:
https://doaj.org/article/9a6f77dcf093444482edec81934a584a
Publikováno v:
PLoS Pathogens, Vol 4, Iss 6, p e1000089 (2008)
Candida albicans strains that are homozygous at the mating type locus (MTLa or MTLalpha) can spontaneously switch at a low frequency from the normal yeast cell morphology (white) to an elongated cell type (opaque), which is the mating-competent form
Externí odkaz:
https://doaj.org/article/47ad6603d32847f38172f098c1122aa2
Autor:
David R. Soll, Daniel F. Lusche, Luis Gonzalez, Sydney E Kelly, Amani Bashir, Elizabeth M Martin, Edward Voss, Claude Pujol, Deborah Wessels, Sneha Phadke, Nikash Pradhan, Michael E. Dailey, Sonia L. Sugg, Yang-Nim Park
Publikováno v:
Cell Adhesion & Migration
article-version (VoR) Version of Record
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 224-248 (2021)
article-version (VoR) Version of Record
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 224-248 (2021)
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs). We demonstrate that MB-231 canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ef524f40b567ae36fc1ba2c6b50477
