Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yang-Dar Yuan"'
Autor:
Ingrid G. Winkler, Kirsten Herbert, Carl R. Walkley, H. Miles Prince, Gemma Haines Olsen, Jean Hendy, Roshantha A.S. Chandraratna, Louise E. Purton, Jean-Pierre Levesque, Yang-Dar Yuan
Publikováno v:
Transplantation. 83:375-384
Failure to mobilize adequate numbers of hematopoietic stem and progenitor cells (HSPC) is an important clinical problem. Since bone marrow (BM) neutrophils play a central role in HSPC mobilization, we hypothesized that granulocyte colony-stimulating
Autor:
Tsung‐Hua Lin, Yang-Dar Yuan, June Chen, David F. Woodward, Larry A. Wheeler, J. Michael Holland, Tim Dinh
Publikováno v:
Cardiovascular Drug Reviews. 23:231-246
Bimatoprost is a safe and well-tolerated intraocular pressure (IOP) lowering drug that was approved in the United States in 2001 for the treatment of glaucoma and ocular hypertension. It is highly efficacious and produces greater mean reductions in I
Autor:
Andrew M. Standeven, Maria Escobar, Roshantha A.S. Chandraratna, Yang-Dar Yuan, Vidyasagar Vuligonda, Richard L. Beard, Scott M. Thacher
Publikováno v:
Biochemical Pharmacology. 62:1501-1509
Hypertriglyceridemia is a major side-effect of retinoid therapy in humans. We previously reported that agonists for the retinoic acid receptors (RARs), but not the retinoid X receptors (RXRs), elevate serum triglycerides in male Fischer rats, and tha
Publikováno v:
Environmental Toxicology and Pharmacology. 3:251-256
The suitability of a dynamic lung slice culture system as an in vitro model for studying pulmonary metabolism of PGF 2 α was assessed. [ 3 H]Prostaglandin F 2 α ([ 3 H]PGF 2 α ), a twenty carbon fatty acid that contains a five-carbon ring and is k
Autor:
Maria Escobar, Yang-Dar Yuan, Andrew M. Standeven, Roshantha A.S. Chandraratna, Richard L. Beard
Publikováno v:
Biochemical Pharmacology. 54:517-524
(E)-2-[2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl) propen-1-yl]-4-thiophenecarboxylic acid (AGN 191701) and other retinoid X receptor (RXR)-selective agonists were observed to cause hepatomegaly in rats. The purpose of the present study w
Autor:
Grant A. McArthur, Roshantha A.S. Chandraratna, Hayley J. Snelling, Hideaki Nakajima, Pierre Chambon, Carl R. Walkley, Yang Dar Yuan, Louise E. Purton
Publikováno v:
Blood. 103(4)
Retinoids are potent inducers of cell cycle arrest and differentiation of numerous cell types, notably granulocytes. However the mechanisms by which retinoids mediate cell cycle arrest during differentiation remain unclear. We have used myeloid diffe
Autor:
Yang-Dar Yuan, George L. Foley
Publikováno v:
Handbook of Toxicologic Pathology (Second Edition)
This chapter discusses about female reproductive toxicologic pathology. Reproductive function in the female is often a noncontinuous cyclic process. The female reproductive tract that ceases to cycle normally because of toxicity can appear similar to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7618390ce80f1c527d41a106f46ae3d1
https://doi.org/10.1016/b978-012330215-1/50044-2
https://doi.org/10.1016/b978-012330215-1/50044-2
Publikováno v:
Prostaglandinsother lipid mediators. 55(5-6)
Natural and synthetic prostanoid agonists were used to study the prostanoid receptors involved in contraction of the mature, isolated uterus of virgin rabbits. The prostanoids elicited contractile responses with a rank order of potency of PGF2 alpha,
Publikováno v:
Environmental Toxicology & Pharmacology. Sep1997, Vol. 3 Issue 4, p251. 6p.