Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Yang NG"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 582-596 (2021)
Promising progress has been made in adoptive transfer of allogeneic natural killer (NK) cells to treat relapsed or refractory acute myeloid leukemia (AML). In this regard, chimeric antigen receptor (CAR)-modification of NK cells is considered as a co
Externí odkaz:
https://doaj.org/article/3132fa6da25c405aa493feb06a356658
Autor:
Win Sen Kuan, Ranjeev Kumar, Ying Wei Yau, Wei Ming Ng, Dennis Wen Jie Chia, Ee Yang Ng, Kanwar Sudhir Lather, Mui Teng Chua
Publikováno v:
Medicina, Vol 59, Iss 7, p 1340 (2023)
Background and Objectives: There is scarce data about the epidemiology, clinical features, investigations, diagnosis, treatment, and outcome in patients attending Singapore emergency departments (EDs) with nontraumatic headache. We sought to describe
Externí odkaz:
https://doaj.org/article/3b61e56d678a4a84babc65e950670c08
Shaping character and life skills for our leaders of tomorrow has always been a challenging task. This exciting new book brings a new perspective to educating our young in a fun, exciting and engaging manner. High energy games that bring about both b
Autor:
Johan C.K. Tay, Junjian Wang, Zhicheng Du, Yu Yang Ng, Zhendong Li, Yuefang Ren, Chang Zhang, Jianqing Zhu, Xue Hu Xu, Shu Wang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 107-120 (2021)
Non-viral platforms can be applied rapidly and cost-effectively for chimeric antigen receptor (CAR)-T cell manufacturing. In the present paper, we describe in detail a clinically relevant manufacturing process for NKG2D CAR-T cells through electropor
Externí odkaz:
https://doaj.org/article/10c7763ffd7c4ca8ae6bfb4382d20b19
Autor:
Alexandre G. Lellouch, Alec R. Andrews, Gaelle Saviane, Zhi Yang Ng, Ilse M. Schol, Marion Goutard, Amon-Ra Gama, Ivy A. Rosales, Robert B. Colvin, Laurent A. Lantieri, Mark A. Randolph, Gilles Benichou, Curtis L. Cetrulo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundVascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is associated with significant morbidity. Induction of immune tolerance of VCAs would permit
Externí odkaz:
https://doaj.org/article/9edd525b71754b0d840e1d03aaddef28
Autor:
Wei Xia Ang, Yu Yang Ng, Lin Xiao, Can Chen, Zhendong Li, Zhixia Chi, Johan Chin-Kang Tay, Wee Kiat Tan, Jieming Zeng, Han Chong Toh, Shu Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 421-430 (2020)
Vγ9Vδ2 T cell-based anticancer immunotherapy has shown some promise in early-phase clinical trials but there is still large room for improvement. Using the extracellular domain of the human NKG2D, a stimulatory receptor expressed by Vγ9Vδ2 T cell
Externí odkaz:
https://doaj.org/article/a1c52e42f75a4abbb2ed5f7dc91ffe5c
Publikováno v:
Molecular Therapy: Oncolytics, Vol 16, Iss , Pp 75-85 (2020)
One reason underlying the failure of current chimeric antigen receptor (CAR) immune therapy to treat solid tumors adequately is insufficient tumor infiltration of CAR immune cells. To address the issue, we electroporated natural killer (NK) cells wit
Externí odkaz:
https://doaj.org/article/baa0a6265cee4079ad1dc92dcb2bfbcf
Publikováno v:
Archives of Plastic Surgery, Vol 47, Iss 02, Pp 194-197 (2020)
Anterior neck burns represent a major reconstructive challenge due to severe sequalae including restriction in movement and poor aesthetic outcomes. Common treatment options include skin grafting with/without dermal matrices, and loco-regional and di
Externí odkaz:
https://doaj.org/article/ebdfa9512a394682ae1f21904eccd27d
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Vγ9Vδ2 T cells are immune effector cells capable of killing multiple myeloma (MM) cells and have been tested in clinical trials to treat MM patients. To enhance the MM cell killing function of Vγ9Vδ2 T cells, we introduced a BCMA-specific CAR int
Externí odkaz:
https://doaj.org/article/c171c1a8b01c41bdbf89b4fb3d59170c
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