Zobrazeno 1 - 10
of 5 188
pro vyhledávání: '"Yang I"'
Publikováno v:
International Journal of Women's Health, Vol Volume 16, Pp 605-617 (2024)
Roza Teshome,1 Irene Yang,2 Edom Woldetsadik,3 Eshetu Girma,4 Melinda Higgins,2 Jessica Wells2 1Department of Midwifery, School of Nursing & Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Nell Hodgson Woodruff
Externí odkaz:
https://doaj.org/article/2b4d5239060845329a02d8dcd4bf7d2c
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 311-323 (2024)
Roza Teshome,1 Irene Yang,2 Edom Woldetsadik,3 Eshetu Girma,4 Melinda Higgins,2 Jessica Wells2 1Department of Midwifery, School of Nursing & Midwifery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Nell Hodgson Woodruff
Externí odkaz:
https://doaj.org/article/5d992c6c1c6f48409b36b63a36eb11f3
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Recent progress in deep learning has greatly improved the prediction of RNA splicing from DNA sequence. Here, we present Pangolin, a deep learning model to predict splice site strength in multiple tissues. Pangolin outperforms state-of-the-a
Externí odkaz:
https://doaj.org/article/04bc34207daa4848812b5fd4ce7a9f97
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Alternative cleavage and polyadenylation (APA), an RNA processing event, occurs in over 70% of human protein-coding genes. APA results in mRNA transcripts with distinct 3′ ends. Most APA occurs within 3′ UTRs, which harbor reg
Externí odkaz:
https://doaj.org/article/22c00d4c07e64f17a1f66809b2181167
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0182301648724efb913023f4fd5460f1
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-28 (2021)
Abstract Background The vast majority of trait-associated variants identified using genome-wide association studies (GWAS) are noncoding, and therefore assumed to impact gene regulation. However, the majority of trait-associated loci are unexplained
Externí odkaz:
https://doaj.org/article/8b8030083d0f4421b999f7d28dd39e81
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
GWAS have identified over 41 susceptibility loci for Parkinson’s disease (PD). Here, the authors integrate PD GWAS summary statistics with transcriptome data from monocytes and DLFPC tissue in a TWAS approach and find 66 significant associations wi
Externí odkaz:
https://doaj.org/article/afa344da02c74e3c8e6b3f277a5732e4
Autor:
Abhishek K Sarkar, Po-Yuan Tung, John D Blischak, Jonathan E Burnett, Yang I Li, Matthew Stephens, Yoav Gilad
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008045 (2019)
Quantification of gene expression levels at the single cell level has revealed that gene expression can vary substantially even across a population of homogeneous cells. However, it is currently unclear what genomic features control variation in gene
Externí odkaz:
https://doaj.org/article/3ceae214409c455fb8382e3025a6c93b
Autor:
Michael Keane, Jeremy Semeiks, Andrew E. Webb, Yang I. Li, Víctor Quesada, Thomas Craig, Lone Bruhn Madsen, Sipko van Dam, David Brawand, Patrícia I. Marques, Pawel Michalak, Lin Kang, Jong Bhak, Hyung-Soon Yim, Nick V. Grishin, Nynne Hjort Nielsen, Mads Peter Heide-Jørgensen, Elias M. Oziolor, Cole W. Matson, George M. Church, Gary W. Stuart, John C. Patton, J. Craig George, Robert Suydam, Knud Larsen, Carlos López-Otín, Mary J. O’Connell, John W. Bickham, Bo Thomsen, João Pedro de Magalhães
Publikováno v:
Cell Reports, Vol 10, Iss 1, Pp 112-122 (2015)
The bowhead whale (Balaena mysticetus) is estimated to live over 200 years and is possibly the longest-living mammal. These animals should possess protective molecular adaptations relevant to age-related diseases, particularly cancer. Here, we report
Externí odkaz:
https://doaj.org/article/5cb71fcc599b4343858c3cc10a216423