Brain physiome: A concept bridging in vitro3D brain models and in silicomodels for predicting drug toxicity in the brain

Autor: Seo, Yoojin, Bang, Seokyoung, Son, Jeongtae, Kim, Dongsup, Jeong, Yong, Kim, Pilnam, Yang, Jihun, Eom, Joon-Ho, Choi, Nakwon, Kim, Hong Nam

Publikováno v: Bioactive Materials; July 2022, Vol. 13 Issue: 1 p135-148, 14p

Brain physiome: A concept bridging in vitro 3D brain models and in silico models for predicting drug toxicity in the brain.

Autor: Seo Y; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea., Bang S; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea., Son J; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Kim D; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Jeong Y; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Kim P; Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea., Yang J; Next&Bio Inc., Seoul, 02841, Republic of Korea., Eom JH; Medical Device Research Division, National Institute of Food and Drug Safety Evaluation, Cheongju, 28159, Republic of Korea., Choi N; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology (UST), Seoul, 02792, Republic of Korea.; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, 02841, Republic of Korea., Kim HN; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology (UST), Seoul, 02792, Republic of Korea.; School of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic of Korea.; Yonsei-KIST Convergence Research Institute, Yonsei University, Seoul, 03722, Republic of Korea.

Publikováno v: Bioactive materials [Bioact Mater] 2021 Nov 12; Vol. 13, pp. 135-148. Date of Electronic Publication: 2021 Nov 12 (Print Publication: 2022).