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Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.

Autor: Metsky HC; Broad Institute of MIT and Harvard, Cambridge, MA, USA. hayden@mit.edu.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA. hayden@mit.edu., Siddle KJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA. kjsiddle@broadinstitute.org.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA. kjsiddle@broadinstitute.org., Gladden-Young A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Qu J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yang DK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Brehio P; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Goldfarb A; Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA., Piantadosi A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA., Wohl S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Carter A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lin AE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Barnes KG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Tully DC; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Corleis B; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Hennigan S; Massachusetts Department of Public Health, Boston, MA, USA., Barbosa-Lima G; Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil., Vieira YR; Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil., Paul LM; Department of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University, Fort Myers, FL, USA., Tan AL; Department of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University, Fort Myers, FL, USA., Garcia KF; Instituto de Investigacion en Microbiologia, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras., Parham LA; Instituto de Investigacion en Microbiologia, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras., Odia I; Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Nigeria., Eromon P; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Nigeria., Folarin OA; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Nigeria.; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Nigeria., Goba A; Lassa Fever Laboratory, Kenema Government Hospital, Kenema, Sierra Leone., Simon-Lorière E; Evolutionary Genomics of RNA Viruses, Virology Department, Institut Pasteur, Paris, France., Hensley L; Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Frederick, MD, USA., Balmaseda A; Laboratorio Nacional de Virología, Centro Nacional de Diagnóstico y Referencia, Ministry of Health, Managua, Nicaragua., Harris E; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA., Kwon DS; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Allen TM; The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Runstadler JA; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA., Smole S; Massachusetts Department of Public Health, Boston, MA, USA., Bozza FA; Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil., Souza TML; Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Rio de Janeiro, Brazil., Isern S; Department of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University, Fort Myers, FL, USA., Michael SF; Department of Biological Sciences, College of Arts and Sciences, Florida Gulf Coast University, Fort Myers, FL, USA., Lorenzana I; Instituto de Investigacion en Microbiologia, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras., Gehrke L; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA., Bosch I; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Ebel G; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA., Grant DS; Lassa Fever Laboratory, Kenema Government Hospital, Kenema, Sierra Leone.; College of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone., Happi CT; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Nigeria.; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Nigeria.; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Nigeria., Park DJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gnirke A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sabeti PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Matranga CB; Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2019 Feb; Vol. 37 (2), pp. 160-168. Date of Electronic Publication: 2019 Feb 04.