Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Yanfei, Tai"'
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Effect of postdose fasting duration on hetrombopag olamine pharmacokinetics and pharmacodynamics in healthy volunteers
Autor: Shuang Yang, Jie Huang, Xingfei Zhang, Ranglang Huang, Qi Pei, Zhijun Huang, Chan Zou, Shen Yan-Cong, Yanfei Tai, Xiao-Yan Yang, Chengxian Guo, Honghui Chen, Guoping Yang
Publikováno v: Br J Clin Pharmacol
Aims Hetrombopag olamine is a novel small-molecule, nonpeptide thrombopoietin receptor agonist developed for immune thrombocytopenia treatment. This study aims to determine the safety and the effect of fasting duration after administration of hetromb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d73e92dde5a5a76ebc0ea6b8a976d35
https://doi.org/10.1111/bcp.14259
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6
Camrelizumab Combined with Chemotherapy Followed by Camrelizumab plus Apatinib as First-line Therapy for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Autor: Linna Wang, Yanfei Tai, Jieer Ying, Yanqiao Zhang, Lin Shen, Yanhong Deng, Jian Jun Zou, Jia Wei, Ying Cheng, Xianglin Yuan, Zhi Peng, Feng Wang, Juxiang Xiao, Kangsheng Gu
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 27(11)
Purpose: Capecitabine plus oxaliplatin (CAPOX) is one of the standard first-line treatments for unresectable, advanced, or metastatic gastric or gastroesophageal junction (G/GEJ) adenocarcinoma. Camrelizumab shows promising antitumor activity in adva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e47086e34bcb7d359c5b0feaec9573
https://pubmed.ncbi.nlm.nih.gov/33766817
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7
Efficacy and safety of a selective URAT1 inhibitor SHR4640 in Chinese subjects with hyperuricaemia: a randomized controlled phase II study
Autor: Liqi Bi, Xiao-Mei Li, Jian Wu, Zhe Zhang, Lian Guo, Qinkai Chen, Xiaoyan Cai, Zhenyu Jiang, Yanwei Lin, Wubin Long, Zhijun Li, Zhongming Wang, Detian Li, Rui Ning, Xin Lu, Ai Peng, Huihua Ding, Xiaoxia Zuo, Yanfei Tai, Xiao-Xiang Chen, Ping Ye, Hong Chen, Lindi Jiang, Gengru Jiang, Jieruo Gu, Chunde Bao, Xiaoxia Wang, Tao Zhang
Publikováno v: Rheumatology (Oxford, England). 60(11)
Objective To evaluate the efficacy and safety of SHR4640, a highly selective urate transporter 1 inhibitor, in Chinese subjects with hyperuricaemia. Methods This was a randomized double-blind dose-ranging phase II study. Subjects whose serum uric aci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f3a8aa32001bc87eef8f4508f996a4
https://pubmed.ncbi.nlm.nih.gov/33693494
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8
Safety and efficacy of hetrombopag in patients with chronic immune thrombocytopenia: a single-arm, open-label, multi-center phase 1 study
Autor: Heng, Mei, Xiequn, Chen, Jianfeng, Zhou, Jianmin, Luo, Qingzhi, Shi, Jing, Liu, Depei, Wu, Guoan, Chen, Yanfei, Tai, Junye, Xiong, Jianjun, Zou, Yu, Hu
Publikováno v: Ann Transl Med
BACKGROUND: Thrombopoietin receptor agonists (TPO‐RAs) are promising therapeutic strategy for patients with immune thrombocytopenia (ITP). We conducted this phase 1 trial (NCT02614846) to evaluate the preliminary efficacy and safety of hetrombopag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ef2d5655316cca06a3a2362a162096
https://doi.org/10.21037/atm-21-4361
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9
A Multicenter, Open-Label, Single-Arm, Phase 2 Study to Evaluate the Efficacy and Safety of Hetrombopag in Patients with Severe Aplastic Anemia (SAA)
Autor: Miao Miao, Jianjun Zou, Tong Chen, Yingmei Li, Yanfei Tai, Guangsheng He, Yi Wang, Hong Chang, Tao Zhang, G X Peng, Fei Li, Pei Li, Sujun Gao, Xinjian Liu, Bo Zhu, Zheng Ge, Shunqing Wang, Yaqi Shen, Xiaoyan Ge, Fengkui Zhang, Bing Han
Publikováno v: Blood. 136:3-4
Introduction: Severe aplastic anemia (SAA) is a hematologic disorder characterized by bone marrow hypoplasia and peripheral pancytopenia. Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) and cyclosporine (CsA) is the standard first-l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cd989bd4aa0ac1613ee3d9b8c04f753
https://doi.org/10.1182/blood-2020-137319
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10
The Impact of a Community-Based Clinical Trial Educational Intervention Among Underrepresented Chinese Americans
Autor: Shumenghui Zhai, Yanfei Tai, Amy Liu, Natasha Blakeney, Margo Michaels, Grace X. Ma, Yin Tan, Xiang S Ma, Brenda F. Seals
Background: Clinical trials are a critical resource for the discovery of new prevention, diagnostic, and treatment methods for cancer. The most effective prevention and treatment modalities are based on previous clinical trial results. However, parti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb038eed99e152eafeea341f275679cb
https://europepmc.org/articles/PMC3951588/
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