Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Yanfa Meng"'
Publikováno v:
Recent patents on anti-cancer drug discovery.
Background: Ribosome-inactivating proteins (RIPs) have been reported to exert anti-tumor and anti-virus activities. A recent patent CN202011568116.7 has developed a new method to prepare Momordica anti-HIV protein of 30 kDa (MAP30). MAP30 is a type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f7243eacab6ea1c63eb967e3d645c
https://pubmed.ncbi.nlm.nih.gov/36330636
https://pubmed.ncbi.nlm.nih.gov/36330636
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101998 (2014)
Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) from Momordica charantia L. have been confirmed to possess anti-tumor and anti-virus activities. Traditional purification methods of these two ribosome-inactivating proteins (RIPs) wer
Externí odkaz:
https://doaj.org/article/802a567b6dea404e972afdc1db7efc72
Publikováno v:
Molecules, Vol 21, Iss 11, p 1457 (2016)
PEGylation is a well-established and effective strategy to decrease immunogenicity, which can increase the stability and in vivo half-life time. However, the generation of multi-site modified products is inevitable due to the lysine chemistry, which
Externí odkaz:
https://doaj.org/article/c58a733c23ad491c8015a6622e8a4964
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Alpha-momorcharin (α-MC), a type I ribosome-inactivating protein (RIP) isolated from Momordica charantia seeds, has been extensively studied for its antitumor, antiviral and antifungal activities. However, as an exogenous protein, problems associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d7986793166b803a2b10a8a0ddf978
http://europepmc.org/articles/PMC6286350
http://europepmc.org/articles/PMC6286350
Publikováno v:
Biotechnology and Applied Biochemistry. 61:165-174
Lipase from Aspergillus terreus was purified to homogeneity using ammonium sulfate precipitation and chromatographies with Q-Sepharose and Sephacryl S-200. It showed a single band on SDS-PAGE and IEF-PAGE with a relative molecular mass of 37.2 kDa an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ec290e9b59cc07883953cdaf76b7fb
https://doi.org/10.1002/bab.1142
https://doi.org/10.1002/bab.1142
Publikováno v:
African Journal of Pharmacy and Pharmacology. 7:1251-1259
Alpha-momorcharin (α-MMC) is a ribosome-inactivating protein (RIP) with antitumor and antiviral activities. α-MMC has a tumoricidal effect on choriocarcinoma, which is a malignant trophoblast-derived tumor that can arise during any type of gestatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d398d013f1dcdc0ab96d7cf59a5bc364
https://doi.org/10.5897/ajpp11.667
https://doi.org/10.5897/ajpp11.667
Autor:
Yanfa Meng, Bo Leng
Publikováno v:
African Journal of Biotechnology; Vol 11, No 68 (2012); 13202-13209
α-Momorcharin (α-MMC) is the ribosome inactivating protein (RIPs) found to possess antitumor activity. However, acute toxicity and short plasma half-life were the major side effects preventing further clinical trial. To overcome this, a-MMC was fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e6ecea02e761e868a42980a7bf0b40
https://www.ajol.info/index.php/ajb/article/view/129164
https://www.ajol.info/index.php/ajb/article/view/129164
Publikováno v:
International Journal of Nanomedicine, Vol 2012, Iss default, Pp 3133-3142 (2012)
International Journal of Nanomedicine
Dove Medical Press
International Journal of Nanomedicine
Dove Medical Press
Video abstract Video
Background Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. Howe
Background Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb7701148e81eccf90f941da6826713
http://www.dovepress.com/preparation-of-an-antitumor-and-antivirus-agent-chemical-modification--a10245
http://www.dovepress.com/preparation-of-an-antitumor-and-antivirus-agent-chemical-modification--a10245
Publikováno v:
Acta Biochimica et Biophysica Sinica. 41:792-799
Ribosome-inactivating proteins (RIPs) are a family of enzymes that depurinate rRNA and inhibit protein biosynthesis. Here we report the purification, apoptosisinducing activity, and polyethylene glycol (PEG) modification of RIP from the bitter melon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd626f0f3ba5a31f1ac275fad457a979
https://doi.org/10.1093/abbs/gmp068
https://doi.org/10.1093/abbs/gmp068
Publikováno v:
Journal of biotechnology. 194
The aim of this study was to improve the ability of Aspergillus terreus lipase to separate the racemic ketoprofen vinyl ester into individual enantiomers using hollow self-assembly alginate- graft -poly(ethylene glycol)/α-cyclodextrins (Alg- g -PEG/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76742cec53abde81104910a41f3c1f1
https://pubmed.ncbi.nlm.nih.gov/25483320
https://pubmed.ncbi.nlm.nih.gov/25483320