Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yanding Zhao"'
Autor:
Yuping Zhou, Baoxia Gu, Geraldine Brichant, Jay Prakash Singh, Huan Yang, Hao Chang, Yanding Zhao, Chao Cheng, Zhong-Wu Liu, Myles H. Alderman, Lingeng Lu, Xiaoyong Yang, Xiao-Bing Gao, Hugh S. Taylor
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the mainte
Externí odkaz:
https://doaj.org/article/865e508108fb429e92551a1d13c63e4e
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106250- (2023)
Summary: RNA-binding proteins (RBPs) have critical roles in N6-methyladenosine (m6A) modification process. We designed a Random Forest (RF) model to systematically analyze the interaction among RBPs and m6A modifications by integrating the binding si
Externí odkaz:
https://doaj.org/article/02dafbf4f5bd41ec987b72d78ac5f7f6
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Chromatin accessibility is essential for transcriptional activation of genomic regions. It is well established that transcription factors (TFs) and histone modifications (HMs) play critical roles in chromatin accessibility regulation. Howeve
Externí odkaz:
https://doaj.org/article/71beec6330d24f74bced0c7a522b5bdb
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6281-6295 (2020)
Abstract Neoadjuvant chemotherapy is the current standard of care for large, advanced, and/or inoperable tumors, including triple‐negative breast cancer. Although the clinical benefits of neoadjuvant chemotherapy have been illustrated through numer
Externí odkaz:
https://doaj.org/article/8bfc6fe182064da3afac39de075ea176
Autor:
Chongming Jiang, Evelien Schaafsma, Wei Hong, Yanding Zhao, Ken Zhu, Cheng-Chi Chao, Chao Cheng
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundNeoantigens are presented on the cancer cell surface by peptide-restricted human leukocyte antigen (HLA) proteins and can subsequently activate cognate T cells. It has been hypothesized that the observed somatic mutations in tumors are shap
Externí odkaz:
https://doaj.org/article/39e94ce6832542629e0c0492f60c8af4
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background Neuroblastoma (NB) is the most common extracranial solid tumor found in children. The frequent gain/loss of many chromosome bands in tumor cells and absence of mutations found at diagnosis suggests that NB is a copy number-driven
Externí odkaz:
https://doaj.org/article/2c3cb04dba314d4b8a92b82fe79b335a
Autor:
Chao Cheng, Keisuke Shirai, Jichang Han, Yanding Zhao, Tyler Searles, Nikhil Khatwani, Jennifer Vella, Fatima Haidar, Fred Kolling, Jiang Gui, Mary Turk, Christina Angeles
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/e4112b67fb7843cdaab7d42db03cb003
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Melanoma is one of the most aggressive cancer types whose prognosis is determined by both the tumor cell-intrinsic and -extrinsic features as well as their interactions. In this study, we performed systematic and unbiased analysis using The Cancer Ge
Externí odkaz:
https://doaj.org/article/487bc62be7e84b86ae4bf0bafbfa5260
Autor:
Yanding Zhao, Robert Carter, Sivaraman Natarajan, Frederick S. Varn, Duane A. Compton, Charles Gawad, Chao Cheng, Kristina M. Godek
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Background Intra-tumor heterogeneity stems from genetic, epigenetic, functional, and environmental differences among tumor cells. A major source of genetic heterogeneity comes from DNA sequence differences and/or whole chromosome and focal c
Externí odkaz:
https://doaj.org/article/97ce881b83ec43f092d71709a1835645
Autor:
Mohamed A. ElTanbouly, Yanding Zhao, Evelien Schaafsma, Christopher M. Burns, Rodwell Mabaera, Chao Cheng, Randolph J. Noelle
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
In recent years, the success of immunotherapy targeting immunoregulatory receptors (immune checkpoints) in cancer have generated enthusiastic support to target these receptors in a wide range of other immune related diseases. While the overwhelming f
Externí odkaz:
https://doaj.org/article/abea92dae8fd454784696491bf1265c9