Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Yandan Yao"'
Autor:
Hao Jin, Yue Chen, Dongbo Zhang, Junfan Lin, Songyin Huang, Xiaohua Wu, Wen Deng, Jiandong Huang, Yandan Yao
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109902- (2024)
Summary: Patients with triple-negative breast cancer (TNBC) frequently experience resistance to chemotherapy, leading to recurrence. The approach of optimizing anti-tumoral immunological effect is promising in overcoming such resistance, given the he
Externí odkaz:
https://doaj.org/article/55cd6e3649ff4e19893429b683ad2b17
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 955-966 (2023)
Monoclonal antibody-based therapy has achieved great success and is now one of the most crucial therapeutic modalities for cancer therapy. The first monoclonal antibody authorized for treating human epidermal growth receptor 2 (HER2)-positive breast
Externí odkaz:
https://doaj.org/article/b1e870c3fd8d4460b5ce01b31cde3fbd
Autor:
Wei Wu, Jiewen Chen, Heran Deng, Liang Jin, Zhanghai He, Nanyan Rao, Yan Nie, Yandan Yao, Yaping Yang, Fengxi Su, Jieqiong Liu
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Here we evaluated the feasibility, efficacy, tolerability, and treatment-mediated immune modulation of neoadjuvant everolimus plus letrozole versus chemotherapy in treating postmenopausal patients with ER-positive, HER2-negative b
Externí odkaz:
https://doaj.org/article/6177ffceb2014b5b9cae1e9c928e4cd6
Publikováno v:
BIO Integration, Vol 1, Iss 4, Pp 156-167 (2021)
In recent years, various research on cancer treatment has achieved significant progress. However, some of these treatments remain disputable because of the emergence and development of drug resistance, and the toxic side effects that were brought abo
Externí odkaz:
https://doaj.org/article/d910b17b0f5f450985489a27337b132c
Autor:
Yuanyuan Li, Bingbin Dong, Wei Wu, Jiawei Wang, Hao Jin, Kangmei Chen, Kangling Huang, Songyin Huang, Yandan Yao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGrowing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer
Externí odkaz:
https://doaj.org/article/3963c6a9a3b9458faca9eebf43131d9f
Autor:
Qingjian Li, Tao Qin, Zhuofei Bi, Huangming Hong, Lin Ding, Jiewen Chen, Wei Wu, Xiaorong Lin, Wenkui Fu, Fang Zheng, Yandan Yao, Man-Li Luo, Phei Er Saw, Gerburg M. Wulf, Xiaoding Xu, Erwei Song, Herui Yao, Hai Hu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Acquired resistance to chemotherapy can lead to multi-drug resistance and poor prognosis in cancer. Here, the authors show that Rac1 increases glycolysis and non-oxidative pentose phosphate pathway activity leading to neoadjuvant chemotherapy (NAC) r
Externí odkaz:
https://doaj.org/article/efec27f7cd8e413ab798c30a495d8ab0
Autor:
Xue Chao, Kai Chen, Jiayi Zeng, Zhuofei Bi, Mingyan Guo, Yi Chen, Yandan Yao, Wei Wu, Shi Liang, Yan Nie
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background As the efficacy of radiotherapy and chemotherapy for treatment of phyllodes tumors (PTs) remains unclear, this study aimed to review all available data and evaluate the roles of radiotherapy and chemotherapy in PT treatment. Metho
Externí odkaz:
https://doaj.org/article/b127fa3b4fe7440f9d627dbef6cdc72f
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Targeted therapy for the cancer immune system has become a clinical reality with remarkable success. Immune checkpoint blockade therapy and chimeric antigen receptor T-cell (CAR-T) immunotherapy are clinically effective in a variety of cancers. Howev
Externí odkaz:
https://doaj.org/article/0db51214edde41098b33b9ed984c0168
Autor:
Songyin Huang, Yang Chen, Zhi-Mei Liang, Na-Na Li, Yujie Liu, Yinghua Zhu, Dingzhun Liao, Xiao Zhen Zhou, Kun Ping Lu, Yandan Yao, Man-Li Luo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Breast cancer is the most prevalent tumor in women worldwide and about 70% patients are estrogen receptor positive. In these cancer patients, resistance to the anticancer estrogen receptor antagonist tamoxifen emerges to be a major clinical obstacle.
Externí odkaz:
https://doaj.org/article/9f8bcec373754f78aa757c66bed16f15
Autor:
Lijia Ni, Xiaoying Xie, Nengyong Ouyang, Baiji Chen, Dongye Wang, Xiaoqiang Liu, Xiquan Wu, Jiajian Guo, Hongyu Li, Yandan Yao, Songyin Huang
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 17, Iss 1, Pp 1-7 (2018)
Abstract Background Cardiobacterium is a fastidious Gram-negative bacillus, and is a rare human pathogen in clinical settings. Herein, we describe a case of Cardiobacterium valvarum (C. valvarum) endocarditis with a rare complication of cerebral hemo
Externí odkaz:
https://doaj.org/article/d0877f7a9591411b9f394f626c4d59ec