Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yanal M Murad"'
Autor:
Fujun Hou, Yuntao Zhang, Xiaohu Liu, Yanal M Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, William Jia, Xiaoming Yang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The recent outbreaks of mpox have raised concerns over the need for effective vaccines. However, the current approved vaccines have either been associated with safety concerns or are in limited supply. mRNA vaccines, which have shown high ef
Externí odkaz:
https://doaj.org/article/a1ef86529e484fa7b1404a32b53e7fc6
Autor:
Zahid Delwar, Olga Tatsiy, Dmitry V. Chouljenko, I-Fang Lee, Guoyu Liu, Xiaohu Liu, Luke Bu, Jun Ding, Manu Singh, Yanal M. Murad, William Wei-Guo Jia
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1805 (2023)
The development of effective cancer vaccines remains a significant challenge due to immune tolerance and limited clinical benefits. Oncolytic herpes simplex virus type 1 (oHSV-1) has shown promise as a cancer therapy, but efficacy is often limited in
Externí odkaz:
https://doaj.org/article/2b25db2b41954448a600579c966045a4
Autor:
Dmitry V. Chouljenko, Jun Ding, I-Fang Lee, Yanal M. Murad, Xuexian Bu, Guoyu Liu, Zahid Delwar, Yi Sun, Sheng Yu, Ismael Samudio, Ronghua Zhao, William Wei-Guo Jia
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 484 (2020)
Oncolytic virotherapy is a promising new tool for cancer treatment, but direct lytic destruction of tumor cells is not sufficient and must be accompanied by strong immune activation to elicit anti-tumor immunity. We report here the creation of a nove
Externí odkaz:
https://doaj.org/article/a6d8ed029b5444409dd42fce8acb87b6
Autor:
Yanal M. Murad, I-Fang Lee, Xiaohu Liu, Zahid Delwar, Jun Ding, Guoyu Liu, Olga Tatsiy, Dmitry Chouljenko, Gregory Hussack, Henk Van Faassen, William Wei-Guo Jia
VG21306 is a novel oncolytic virus (OV) that encodes a secretable bispecific T-cell engager targeting Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6)-expressing tumors. Delivering a T-cell engager locally to a tumor mass will circumvent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37ea6bc212e0c49a9651812dc954196
https://doi.org/10.1101/2023.01.02.522257
https://doi.org/10.1101/2023.01.02.522257
Autor:
Jun Ding, Yanal M. Murad, Yi Sun, I-Fang Lee, Ismael Samudio, Xiaohu Liu, William Wei-Guo Jia, Ronghua Zhao
Publikováno v:
Viruses; Volume 14; Issue 11; Pages: 2327
Oncolytic viruses (OVs) can specifically replicate in the host and cause cancer cell lysis while inducing an antitumor immune response. The aim of this study is to investigate the impact of either pre-existing immunity against herpes simplex virus ty
Autor:
Guoyu Liu, Ronghua Zhao, Zahid Delwar, I-Fang Lee, Jia William, Chouljenko Dmitry, Sheng Yu, Ismael Samudio, Jun Ding, Yanal M. Murad, Xuexian Bu, Yi Sun
Publikováno v:
Biomedicines, Vol 8, Iss 484, p 484 (2020)
Biomedicines
Volume 8
Issue 11
Biomedicines
Volume 8
Issue 11
Oncolytic virotherapy is a promising new tool for cancer treatment, but direct lytic destruction of tumor cells is not sufficient and must be accompanied by strong immune activation to elicit anti-tumor immunity. We report here the creation of a nove
Publikováno v:
Blood. 138:1169-1169
Acute myeloid leukemia (AML) is the most common human leukemia and is a major area of unmet medical need among hematologic malignancies. Progress has been made in identifying therapeutic targets and several approved therapies, but resistance to front
Autor:
Luke Ardolino, Ronghua Zhao, Eugene Hsu, Rasha Cosman, Neha Aggarwal, Anthony M. Joshua, William Jia, Aaron O'Grady, Erica Lee, Yanal M. Murad, Huiqun Xia, Yiting Chi, Shi Qui
Publikováno v:
Journal of Clinical Oncology. 39:e14574-e14574
e14574 Background: Oncolytic virus (OV) can specifically replicate in cancer cells causing cell lysis. Together with the expression of immune stimulating payloads, OV can induce an anti-tumor immune response. The aim of this study is to assess the sa
Autor:
Luke Bu, Shuyun Liu, William Jia, Ronghua Zhao, Erica Lee, Guoyu Liu, Tianchi Liu, Yanal M. Murad, Chouljenko Dmitry, Jun Ding
Publikováno v:
Cancer Immunology Research. 8:B85-B85
Oncolytic viruses (OVs) are the wild-type or genomic modified viruses, which can specifically replicate in cancer cells but not in normal cells. They cause cancer cell lysis and more importantly, their replication in tumor cells induces an antitumor
Autor:
Guoyu Liu, Dmitry Choujenko, Ronghua Zhao, Jun Ding, William Jia, Luke Bu, Erica Lee, Yanal M. Murad
Publikováno v:
Cancer Immunology Research. 7:B059-B059
Oncolytic viruses (OVs) are among the most powerful approaches in cancer immunotherapy. OVs not only cause cancer cell lysis but more importantly, their infection in tumors induces anti-tumor immune response from the host, resulting in lasting anti-t