Výsledky vyhledávání - "Yana Sharpadskaya"

Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles

Autor: Kevin Boye, Lauren Anderson-Pullinger, Felix Boos, Carmen Bekeova, Johannes M. Herrmann, Erin L. Seifert, Yana Sharpadskaya

Publikováno v: J Biol Chem

Acyl-CoA thioesterases (Acots) hydrolyze fatty acyl-CoA esters. Acots in the mitochondrial matrix are poised to mitigate β-oxidation overload and maintain CoA availability. Several Acots associate with mitochondria, but whether they all localize to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcd0af025e76eaf3d293f90706212a9
https://pubmed.ncbi.nlm.nih.gov/31676684

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Multiple acyl-CoA thioesterases occupy distinct functional niches within the mitochondrial matrix

Autor: Carmen Bekeova, Erin L. Seifert, Johannes M. Herrmann, Kevin Boye, Felix Boos, Lauren Anderson-Pullinger, Yana Sharpadskaya

SUMMARYAcyl-CoA thioesterases (Acots) hydrolyze fatty acyl-CoA esters. Acots in the mitochondrial matrix are poised to mitigate β-oxidation overload that may contribute to lipotoxicity. Several Acots associate with mitochondria, but whether they all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216569c1b62491ec17c8ebff19da8568