Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yana Miteva"'
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001267 (2011)
The molecular mechanisms of animal cell osmoregulation are poorly understood. Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. Whether mucins play si
Externí odkaz:
https://doaj.org/article/e2014672d5fe4a06a31f914fc1dbccea
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9010 (2010)
The soil-dwelling nematode C. elegans is a powerful system for comparative molecular analyses of environmental stress response mechanisms. Infection of worms with bacterial and fungal pathogens causes the activation of well-characterized innate immun
Externí odkaz:
https://doaj.org/article/e3142e04edc2454993c8ca70fa7e6396
Publikováno v:
Oncotarget
Many DNA repair factors act to suppress tumor formation by preserving genomic stability. Similarly, the CtIP protein, which interacts with the BRCA1 tumor suppressor, is also thought to have tumor suppression activity. Through its role in DNA end res
Autor:
Dante P. Ricci, Emre Koyuncu, Thomas Shenk, Thomas J. Silhavy, Yana Miteva, Ileana M. Cristea, Hanna G. Budayeva
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
mBio
mBio
The seven human sirtuins are a family of ubiquitously expressed and evolutionarily conserved NAD+-dependent deacylases/mono-ADP ribosyltransferases that regulate numerous cellular and organismal functions, including metabolism, cell cycle, and longev
Autor:
Ileana M. Cristea, Yana Miteva
Publikováno v:
Molecularcellular proteomics : MCP. 13(1)
Sirtuin 6 (SIRT6), a member of the mammalian sirtuin family, is a nuclear deacetylase with substrate-specific NAD(+)-dependent activity. SIRT6 has emerged as a critical regulator of diverse processes, including DNA repair, gene expression, telomere m
Publikováno v:
Development (Cambridge, England). 140(11)
The epicardium is a mesothelial cell layer essential for vertebrate heart development and pertinent for cardiac repair post-injury in the adult. The epicardium initially forms from a dynamic precursor structure, the proepicardial organ, from which ce
Autor:
Erin Kaltenbrun, Todd M. Greco, Lauren Waldron, Ileana M. Cristea, Frank L. Conlon, Yana Miteva
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799914
The immunoaffinity isolation of protein complexes is an essential technique for the purification and concentration of protein complexes from cells and tissues. In this chapter we present the methodologies for the purification of proteins and protein
Publikováno v:
Molecularcellular proteomics : MCP. 11(5)
Among mammalian sirtuins, SIRT7 is the only enzyme residing in nucleoli where ribosomal DNA is transcribed. Recent reports established that SIRT7 associates with RNA Pol I machinery and is required for rDNA transcription. Although defined by its homo
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799914
Proteomic characterization of protein complexes leverages the versatile platform of liquid chromatography-tandem mass spectrometry to elucidate molecular and cellular signaling processes underlying the dynamic regulation of macromolecular assemblies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e07cdb0b115f6854c1faa06993f437c
https://doi.org/10.1007/978-1-61779-992-1_22
https://doi.org/10.1007/978-1-61779-992-1_22
Autor:
Ruedi Aebersold, Wade H. Dunham, Tony Pawson, Nicole St-Denis, Simon Hauri, Annie Bouchard, Daniel Durocher, Keiryn L. Bennett, Zhen Yuan Lin, Mihaela E. Sardiu, Anne-Claude Gingras, Rob M. Ewing, Damian Fermin, Vincentius A. Halim, Amber L. Couzens, Tuo Li, Shabaz Mohammed, Michael P. Washburn, Hyungwon Choi, Beatriz Gonzalez Badillo, Brian Raught, Nina C. Hubner, Marilyn Goudreault, Jacques Colinge, Zachary Wright, Dattatreya Mellacheruvu, Alexey I. Nesvizhskii, Ileana M. Cristea, Denis Faubert, Matthias Gstaiger, Abdallah Al-Hakim, Yana Miteva, Teck Yew Low, Giulio Superti-Furga, Richard D. Bagshaw, Benoit Coulombe, Jean-Philippe Lambert, Albert J. R. Heck
Publikováno v:
Nature methods
Nature Methods, 10, 730. Nature Publishing Group
Nature Methods, 10, 730
Nature Methods, 10, 8, pp. 730
Nature Methods, 10, 730. Nature Publishing Group
Nature Methods, 10, 730
Nature Methods, 10, 8, pp. 730
Affinity purification coupled with mass spectrometry (AP-MS) is a widely used approach for the identification of protein-protein interactions. However, for any given protein of interest, determining which of the identified polypeptides represent bona