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Autor:
Shantanu Sule, Suli Liu, Vincent J. Mecozzi, Allan D. Capili, William C. Yang, Kapil Gupta, Jason E. Fernandez, Li Zang, Tia Estey, Pamela Feng, Yana Kravets
Publikováno v:
Journal of pharmaceutical sciences. 106(12)
Characterizing molecular charge variants or isoforms is essential for understanding safety, potency, and bioavailability of antibody therapeutics. However, there is little information on how they influence stability and viscosity-properties governing