Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yana, Pang"'
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Synaptic dysfunction with reduced synaptic protein levels is a core feature of Alzheimer’s disease (AD). Synaptic proteins play a central role in memory processing, learning, and AD pathogenesis. Evidence suggests that synaptic
Externí odkaz:
https://doaj.org/article/1170492fc4e04d97b1c19081ceed67f7
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Plasma amyloid-β (Aβ)42, phosphorylated tau (p-tau)181, and neurofilament light chain (NfL) are promising biomarkers of Alzheimer’s disease (AD). However, whether these biomarkers can predict AD in Chinese populations is yet to be fully
Externí odkaz:
https://doaj.org/article/8d845ef6b3b14dac8e326f1da4da33ca
Autor:
Wenwen Li, Yana Pang, Yan Wang, Fan Mei, Mengmeng Guo, Yiping Wei, Xinyue Li, Wei Qin, Wei Wang, Longfei Jia, Jianping Jia
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background The identification of pathogenic mutations in Alzheimer’s disease (AD) causal genes led to a better understanding of the pathobiology of AD. Familial Alzheimer’s disease (FAD) is known to be associated with mutations in the AP
Externí odkaz:
https://doaj.org/article/bc7fc09fd1e34b7bb4cc4f8c58b8509b
Autor:
Huimin Cai, Yana Pang, Qi Wang, Wei Qin, Cuibai Wei, Ying Li, Tingting Li, Fangyu Li, Qigeng Wang, Yan Li, Yiping Wei, Longfei Jia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Neuronal- and astrocyte-derived exosomes have been identified as an optimal source for screening biomarkers for Alzheimer’s disease (AD). However, few studies focus on the bulk exosome population isolated from plasma of AD. This
Externí odkaz:
https://doaj.org/article/165c036d5935428787fe0c9d088d2f86
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-10 (2022)
Abstract Background Circular RNAs (circRNAs) have been demonstrated to be associated with Alzheimer’s disease (AD). Here, we conducted a study to explore whether circRNAs have the ability to differentiate AD from cognitively normal controls and oth
Externí odkaz:
https://doaj.org/article/96f9c9f5b9a44cd0996b039dfdf949cc
Autor:
Longfei Jia, Min Zhu, Jianwei Yang, Yana Pang, Qi Wang, Ying Li, Tingting Li, Fangyu Li, Qigeng Wang, Yan Li, Yiping Wei
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background The most common biomarkers of Alzheimer’s disease (AD) are amyloid β (Aβ) and tau, detected in cerebrospinal fluid (CSF) or with positron emission tomography imaging. However, these procedures are invasive and expensive, which
Externí odkaz:
https://doaj.org/article/1a5ed875f62646dea79fa1c3a91d7bad
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102654- (2022)
Frontotemporal dementia (FTD) caused by microtubule-associated protein tau (MAPT) mutations is not rare and is almost fully penetrant. However, no disease-modifying treatment for FTD is currently available. Here, we demonstrated the establishment and
Externí odkaz:
https://doaj.org/article/78d5d81d17174822b679229ed8c59ed6
Publikováno v:
Journal of Neurology. 270:2117-2127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3ebfd6647919c91a0a2b18ce2cd6ae
https://doi.org/10.1007/s00415-023-11558-9
https://doi.org/10.1007/s00415-023-11558-9
Publikováno v:
Molecular Neurobiology. 60:566-575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e7a0ad1415bf5014716dd589424e158
https://doi.org/10.1007/s12035-022-03105-w
https://doi.org/10.1007/s12035-022-03105-w
Publikováno v:
Journal of neurology.
Messenger RNAs (mRNAs) have been reported to be associated with Alzheimer's disease (AD). In this study, we investigated whether plasma-based mRNAs could distinguish AD from cognitively normal controls and other types of dementia, including vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b93a69edda0149ab6fb7ef7a510832f
https://pubmed.ncbi.nlm.nih.gov/36611114
https://pubmed.ncbi.nlm.nih.gov/36611114