Zobrazeno 1 - 10
of 69
pro vyhledávání: '"YanWen Yang"'
Autor:
Ashutosh Singh, Donghang Cheng, Jyothishmathi Swaminathan, Yanwen Yang, Yan Zheng, Nancy Gordon, Vidya Gopalakrishnan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The RE1 silencing transcription factor (REST) is a driver of sonic hedgehog (SHH) medulloblastoma genesis. Our previous studies showed that REST enhances cell proliferation, metastasis and vascular growth and blocks neuronal differentiation
Externí odkaz:
https://doaj.org/article/1ed74e9c2f9940068158fa62483d53f1
Autor:
Lu Wang, Kangjie Shen, Zixu Gao, Ming Ren, Chenlu Wei, Yang Yang, Yinlam Li, Yu Zhu, Simin Zhang, Yiteng Ding, Tianyi Zhang, Jianrui Li, Ming Zhu, Shaoluan Zheng, Yanwen Yang, Shisuo Du, Chuanyuan Wei, Jianying Gu
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Radiotherapy (RT) can induce tumor regression outside the irradiation field, known as the abscopal effect. However, the detailed underlying mechanisms remain largely unknown. A tumor‐bearing mouse model is successfully constructed by induc
Externí odkaz:
https://doaj.org/article/d1fb606c2e424709a8405261cdc2c26f
Autor:
Chuanyuan Wei, Wei Sun, Kangjie Shen, Jingqin Zhong, Wanlin Liu, Zixu Gao, Yu Xu, Lu Wang, Tu Hu, Ming Ren, Yinlam Li, Yu Zhu, Shaoluan Zheng, Ming Zhu, Rongkui Luo, Yanwen Yang, Yingyong Hou, Fazhi Qi, Yuhong Zhou, Yong Chen, Jianying Gu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Acral melanoma (AM) is a rare subtype of melanoma characterized by a high incidence of lymph node (LN) metastasis, a critical factor in tumor dissemination and therapeutic decision-making. Here, we employ single-cell and spatial transcriptom
Externí odkaz:
https://doaj.org/article/ee35eeed1e244341a06847f1bd0adb20
Autor:
Kangjie Shen, Wenyu Song, Hongye Wang, Lu Wang, Yang Yang, Qianrong Hu, Min Ren, Zixu Gao, Qiangcheng Wang, Shaoluan Zheng, Ming Zhu, Yanwen Yang, Yong Zhang, Chuanyuan Wei, Jianying Gu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Metastasis is a formidable challenge in the prognosis of melanoma. Accurately predicting the metastatic potential of non-metastatic melanoma (NMM) and determining effective postoperative adjuvant treatments for inhibiting metastasis remain u
Externí odkaz:
https://doaj.org/article/c8d5e95afefb4072ae5616eadb823832
Autor:
Kangjie Shen, Qiangcheng Wang, Lu Wang, Yang Yang, Min Ren, Yanlin Li, Zixu Gao, Shaoluan Zheng, Yiteng Ding, Jiani Ji, Chenlu Wei, Tianyi Zhang, Yu Zhu, Jia Feng, Feng Qin, Yanwen Yang, Chuanyuan Wei, Jianying Gu
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-16 (2023)
Abstract Background Melanoma is the deadliest form of skin tumor, and G protein-coupled receptors (GPCRs) play crucial roles in its carcinogenesis. Furthermore, the tumor microenvironment (TME) affects the overall survival (OS) and the response to im
Externí odkaz:
https://doaj.org/article/699205f269ec4a7aacac4a44cfe017c9
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Skin cutaneous melanoma (SKCM) is the most lethal tumor among three of the major malignant cancers of the skin. The mechanism underlying the malignant biological behaviors of SKCM is not fully clear. Our study intended to verify the molecula
Externí odkaz:
https://doaj.org/article/8b3e25836b554ec5979f5d59cf208f99
Autor:
Zixu Gao, Lu Wang, Zhengqing Song, Ming Ren, Yang Yang, Jianrui Li, Kangjie Shen, Yinlam Li, Yiteng Ding, Yanwen Yang, Yuhong Zhou, Chuanyuan Wei, Jianying Gu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAs a novel immune checkpoint, CD73 has been reported to play prominent roles in several malignancies. However, the significance of CD73 in melanoma remains ambiguous. This study sought to reveal the impact of CD73 on the tumor microenvironm
Externí odkaz:
https://doaj.org/article/c91d5eb691d24219a4efa243140ba754
Autor:
Shavali Shaik, Shinji Maegawa, Amanda R Haltom, Feng Wang, Xue Xiao, Tara Dobson, Ajay Sharma, Yanwen Yang, Jyothishmathi Swaminathan, Vikas Kundra, Xiao Nan Li, Keri Schadler, Arif Harmanci, Lin Xu, Vidya Gopalakrishnan
Publikováno v:
Molecular Oncology, Vol 15, Iss 5, Pp 1486-1506 (2021)
Expression of the RE1‐silencing transcription factor (REST), a master regulator of neurogenesis, is elevated in medulloblastoma (MB) tumors. A cell‐intrinsic function for REST in MB tumorigenesis is known. However, a role for REST in the regulati
Externí odkaz:
https://doaj.org/article/2fd985365fb74e1ca2c9a58c50c1a78b
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Cell proliferation and death are key components of wound healing and tissue repair. Telocytes (TCs) represent a newly discovered cell type that can protect tissue from acute injury via cell–cell communication with adjacent cells
Externí odkaz:
https://doaj.org/article/1e0512bab1ca4fefb11f02245efc1147
Autor:
Jennifer Ann Foltz, Srinivas S Somanchi, Yanwen Yang, Arianexys Aquino-Lopez, Erin Elizabeth Bishop, Dean Anthony Lee
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Canines spontaneously develop many cancers similar to humans - including osteosarcoma, leukemia, and lymphoma - offering the opportunity to study immune therapies in a genetically heterogeneous and immunocompetent environment. However, a lack of anti
Externí odkaz:
https://doaj.org/article/1adb3d4d729f4e49b64943e7fd0d5244