Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yan-yun Ruan"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
MicroRNA (miR)-1246 is abnormally expressed and has pro-oncogenic functions in multiple types of cancer. In the present study, its functions in breast cancer and the underlying mechanisms were further elucidated. The clinical relevance of miR-1246 wa
Externí odkaz:
https://doaj.org/article/00d0608b71ad4e178d6f10bd52449bb2
Publikováno v:
Human Immunology. 77:780-784
HLA-G is an immune tolerant with seven isoforms. HLA-G expression was observed to be associated with tumor cell immune escaping, invasion and metastasis, and with poor prognosis in cancer patients. Different types of HLA-G isoforms could be expressed
Publikováno v:
Human Immunology. 77:317-324
Human leukocyte antigen-G (HLA-G) is a novel tumor marker. Increased level of soluble HLA-G (sHLA-G) in various tumor types has been reported. However, the potential diagnostic value of sHLA-G with other tumor markers in gastric cancer (GC) diagnosis
Publikováno v:
Oncotarget
// Jing-Bo Li 1 , Yan-Yun Ruan 2 , Bin Hu 1 , Shan-Shan Dong 2 , Tie-Nan Bi 3 , Aifen Lin 2 and Wei-Hua Yan 1, 4 1 Medical Research Center, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, Zhejiang, People’s Republic of Ch
Publikováno v:
Human Immunology. 73:946-949
The immunotolerant human leukocyte antigen (HLA)-G has direct inhibitory effects on natural killer cells, dendritic cells, T cells and can indirectly induce tolerant regulatory cells. The significance of the aberrant HLA-G expression in malignant con
Publikováno v:
International Journal of Cancer. 132:82-89
Alteration of human leukocyte antigen (HLA) expression, such as decreased HLA I (HLA-A, -B and -C) antigens and elevated nonclassical HLA I antigens (HLA-E, -F and -G), was reported to have an unfavorable prognosis in various cancers. In our study, H
Publikováno v:
International Journal of Immunogenetics. 38:13-16
Interleukin 1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule encoded by the IL1RN gene. The polymorphism of IL1RN characterized by variable numbers of an 86 bp tandem repeat (VNTR) sequence in intron 2 has been described. Mor
Publikováno v:
Human immunology. 75(2)
The immunotolerant HLA-G could generate seven isoforms including HLA-G1--G7. The suppressive function of either HLA-G1 or HLA-G5 isoform to NK cell cytolysis has been well established. Whether HLA-G1 and HLA-G5 isoform have an additive effect on the
Publikováno v:
International journal of cancer. 131(1)
Aberrant HLA-G expression is associated with tumor invasiveness and poor clinical prognosis; however, there is a lack of preclinical animal model to address whether HLA-G plays a causal role in the unfavorable prognosis of malignancies. In the curren
Publikováno v:
Leukemia research. 35(10)
Human leukocyte antigen (HLA)-G could contribute to escape of cancer cells from host anti-tumor responses, and its potential clinical relevance in various malignancies was also addressed. However, the prognostic value of HLA-G in acute myeloid leukem