Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yan-rong Ma"'
Publikováno v:
Ultrasonics Sonochemistry, Vol 111, Iss , Pp 107153- (2024)
Millet protein, as a promising plant-based protein substitute source, is an excellent basis for essential amino acids compared to commonly consumed staple grains. Compared with the traditional extraction process, ultrasound has been used to enhance t
Externí odkaz:
https://doaj.org/article/f2cec7f1b19e4ed3a660a12e40b30e62
Publikováno v:
Biopharmaceutics & Drug Disposition. 43:255-264
Two-thirds of patients with type 2 diabetes mellitus have hypertension, and thus the combination of two or more drugs to treat these diseases is common. It has been shown that the combination of metformin and enalapril has beneficial effects, but few
Publikováno v:
Asian Journal of Pharmaceutical Sciences
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 519-529 (2021)
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 519-529 (2021)
The liver is an important organ for drugs disposition, and thus how to accurately evaluate hepatic clearance is essential for proper drug dosing. However, there are many limitations in drug dosage adjustment based on liver function and pharmacogenomi
Autor:
Kan Li, Li Gao, Sen Zhou, Yan-Rong Ma, Xiao Xiao, Qian Jiang, Zhi-Hong Kang, Ming-Long Liu, Tian-Xi Liu
Publikováno v:
Molecular and cellular biochemistry.
Acute kidney injury (AKI) is one of frequent complications of sepsis with high mortality. Mitochondria is the center of energy metabolism participating in the pathogenesis of sepsis-associated AKI, and SIRT1/PGC1-α signaling pathway plays a crucial
Autor:
Tian-xi Liu, Yi-Qing Wang, Long-Zhen Shi, Bin Li, Yan-Rong Ma, Ming-Long Liu, Cheng Chen, Rong Wu, Kan Li, Jun-Feng Li
Publikováno v:
Biochemical and Biophysical Research Communications. 517:557-565
Background Nowadays, people diagnosed sepsis may develop acute kidney injury (AKI), resulting heavy burden of health care. Recombinant human erythroprotein (rhEPO) has been suggested to have multifunction and may be used in the prevention or treatmen
Publikováno v:
Life Sciences. 224:41-50
Common characteristics of drug induced nephrotoxicity are renal tubular and interstitial injury. Many studies have only focused on renal tubular injury. However, less is known about the effects of drugs in the renal interstitium on the nephrotoxicity
Autor:
Yong-wen Jin, Yan Zhou, Xinan Wu, Wen-Kou, Fan Zhang, Zhi Rao, Guo-qiang Zhang, Yan-rong Ma, Boxia Li
Publikováno v:
Current Pharmaceutical Analysis. 15:121-129
Background:Imatinib (IM) is a chemotherapy medication metabolized by CYP3A4 to Ndesmethyl imatinib (NDI), which shows similar pharmacologic activity to the parent drug. Although methods for determination of IM and/or NDI have been developed extensive
Publikováno v:
Biopharmaceutics & Drug Disposition. 40:3-11
Metformin is always used as the baseline antidiabetic therapy for patients with type 2 diabetes mellitus (T2DM) and hyperuricemia. Metformin is excreted into urine through active secretion mediated by rOCTs and rMATE1.The aim of this study was to ide
Autor:
Xinan Wu, Yan Zhou, Yong-wen Jin, Zhi Rao, Yan-rong Ma, Xing-dong Wang, Guo-qiang Zhang, A-xi Shi
Publikováno v:
Current Pharmaceutical Analysis. 14:331-341
Background: It is still uncertain whether the accumulation of the bile acids (BAs) in hepatocytes beyond the normal stand after taking medicine which can cause hepatic injury or under the pathological state. Because it is lack of valid and simple ana
Publikováno v:
Life Sciences. 196:110-117
The renal excretion of creatinine and most drugs are the net result of glomerular filtration and tubular secretion, and their tubular secretions are mediated by individual transporters. Thus, we hypothesized that the increase of serum creatinine (SCr