Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yan-qing Yin"'
Autor:
Shu Yin, Xin-yue Ma, Ying-feng Sun, Yan-qing Yin, Ying Long, Chun-lai Zhao, Jun-wei Ma, Sen Li, Yan Hu, Ming-tao Li, Gang Hu, Jia-wei Zhou
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Astrocytes contribute to chronic neuroinflammation in a variety of neurodegenerative diseases, including Parkinson's disease (PD), the most common movement disorder. However, the precise role of astrocytes in neuroinflammation remains incomp
Externí odkaz:
https://doaj.org/article/54b411ae89054fc88270909e3dad6f2a
Autor:
Shu-zhen Zhang, Qin-qin Wang, Qiao-qiao Yang, Huan-yu Gu, Yan-qing Yin, Yan-dong Li, Jin-can Hou, Rong Chen, Qing-qing Sun, Ying-feng Sun, Gang Hu, Jia-wei Zhou
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-22 (2019)
Abstract Background Brain innate immunity is vital for maintaining normal brain functions. Immune homeostatic imbalances play pivotal roles in the pathogenesis of neurological diseases including Parkinson’s disease (PD). However, the molecular and
Externí odkaz:
https://doaj.org/article/eb584bece9eb49d78bbbaf616271f2e9
Autor:
Shen-zhao Lu, Yong-shun Guo, Pei-zhou Liang, Shu-zhen Zhang, Shu Yin, Yan-qing Yin, Xiao-min Wang, Fei Ding, Xiao-song Gu, Jia-wei Zhou
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-14 (2019)
Abstract Background Parkinson’s disease (PD) is characterized by a chronic loss of dopaminergic neurons and the presence of proteinaceous inclusions (Lewy bodies) within some remaining neurons in the substantia nigra. Recently, astroglial inclusion
Externí odkaz:
https://doaj.org/article/3e0fe95a06644468a2c1fd6f8ff4b7ef
Autor:
Qiao-qiao Yang, Ying-qi Zhai, Hai-fang Wang, Yu-chen Cai, Xin-yue Ma, Yan-qing Yin, Yan-dong Li, Guo-min Zhou, Xu Zhang, Gang Hu, Jia-wei Zhou
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109127- (2021)
Summary: The hippocampus is one of two niches in the mammalian brain with persistent neurogenesis into adulthood. The neurogenic capacity of hippocampal neural stem cells (NSCs) declines with age, but the molecular mechanisms of this process remain u
Externí odkaz:
https://doaj.org/article/32f61b09ddbd4553995f0641ba480b60
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Microglia play a critical role in the pathogenic process of neurodegenerative diseases, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD). Upon pathological stimulation, microglia are converted from a surveillant to an overactivated p
Publikováno v:
Neuroscience research. 180
Parkinson's disease (PD) is an age-related neurodegenerative disease, mainly characterized by the loss of dopaminergic (DA) neurons in the substantia nigra. Several non-motor symptoms, including those associated with gastrointestinal dysfunction, pre
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/21/2023, Vol. 120 Issue 8, p1-12, 21p
Autor:
Shen-zhao Lu, Yue Wu, Yong-shun Guo, Pei-zhou Liang, Shu Yin, Yan-qing Yin, Xiu-li Zhang, Yan-Fang Liu, Hong-yan Wang, Yi-chuan Xiao, Xin-miao Liang, Jia-wei Zhou
Publikováno v:
The Journal of experimental medicine. 219(9)
Astrocyte activation is associated with progressive inflammatory demyelination in multiple sclerosis (MS). The molecular mechanisms underlying astrocyte activation remain incompletely understood. Recent studies have suggested that classical neurotran
Publikováno v:
MATEC Web of Conferences, Vol 44, p 02018 (2016)
The three-dimensional-quantitative structure activity relationship (3D-QSAR) studies were performed on a series of direct factor Xa (FXa) inhibitors using AutoGPA-based modeling method in this paper. A training set of 38 molecules and a test set cont
Externí odkaz:
https://doaj.org/article/7922a0d5e9ff4a139b9076e5ec680c72
Autor:
Xiao-Dong Yang, Yi-Min Shi, Wen Chen, Shu-Ya Zhou, Li-Juan Yang, Yan-Qing Yin, Shui-Xian Ma, Hui-Lin Cheng
Publikováno v:
Journal of Molecular Structure. 1058:181-188
The inclusion complexation behavior, characterization and binding ability of pinocembrin with β-cyclodextrin (β-CD) and its derivative 2-hydroxypropyl-β-cyclodextrin (HPβCD) were investigated in both solution and the solid state by means of XRD,