Výsledky vyhledávání - "Yan-Zheng He"

Dissertation/ Thesis

Dissection of TGF-beta/Smads in the renal inflammation and fibrosis.

目的：转化生长因子－1（TGF-β1）通过与II型受体结合而引起I型受体活化，进一步激活其下游信号分子蛋白Smad2 和Smad3，它们与Smad4（Co-Smad）结合后形成Smad复合体并发生核转移，从而发挥广�

Externí odkaz: http://library.cuhk.edu.hk/record=b5549453
http://repository.lib.cuhk.edu.hk/en/item/cuhk-328224

Akademický článek

AGEs-Induced Calcification and Apoptosis in Human Vascular Smooth Muscle Cells Is Reversed by Inhibition of Autophagy

Autor: Hu-Qiang He, Yuan-Qing Qu, Betty Yuen Kwan Law, Cong-ling Qiu, Yu Han, Ivo Ricardo de Seabra Rodrigues Dias, Yong Liu, Jie Zhang, An-Guo Wu, Cheng-Wen Wu, Simon Wing Fai Mok, Xin Cheng, Yan-Zheng He, Vincent Kam Wai Wong

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Vascular calcification (VC) in macrovascular and peripheral blood vessels is one of the main factors leading to diabetes mellitus (DM) and death. Apart from the induction of vascular calcification, advanced glycation end products (AGEs) have also bee

Externí odkaz: https://doaj.org/article/4b7f905b414c44b99a985a416da7afa0

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Akademický článek

Bavachin Protects Human Aortic Smooth Muscle Cells Against β-Glycerophosphate-Mediated Vascular Calcification and Apoptosis via Activation of mTOR-Dependent Autophagy and Suppression of β-Catenin Signaling

Autor: Hu-Qiang He, Betty Yuen Kwan Law, Ni Zhang, Cong-ling Qiu, Yuan-Qing Qu, An-Guo Wu, Yu Han, Qi Song, Wen-Lu Zheng, Yong Liu, Yan-Zheng He, Vincent Kam Wai Wong

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Vascular calcification is a major complication of cardiovascular disease and chronic renal failure. Autophagy help to maintain a stable internal and external environment that is important for modulating arteriosclerosis, but its pathogenic mechanism

Externí odkaz: https://doaj.org/article/cf0499e2515f42ce8137877d7275d536

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Endothelial Cells Inhibit the Angiotensin II Induced Phenotypic Modulation of Rat Vascular Adventitial Fibroblasts

Autor: Jia-Ying, Xu, Neng-Bin, Chang, Tao, Li, Rui, Jiang, Xiao-Lei, Sun, Yan-Zheng, He, Jun, Jiang

Publikováno v: Journal of cellular biochemistry. 118(7)

The phenotypic modulation of vascular adventitial fibroblasts plays an important role in vascular remodeling. Evidence have shown that endothelial cells and adventitial fibroblasts interact under certain conditions. In this study, we investigated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e831121b2fb85170dab5911f567bc46
https://pubmed.ncbi.nlm.nih.gov/28218456

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Experimental study on apoptosis of TNFR1 receptor pro-endothelial progenitor cells activated by high glucose induced oxidative stress

Autor: Yong, Liu, Fei, Xei, Xiong-Fei, Xu, Hong, Zeng, Hu-Qiang, He, Lei, Zhang, Ying-Qiang, Zheng, Yan-Zheng, He

Publikováno v: International journal of clinical and experimental medicine. 8(11)

Objective: To investigate whether high glucose in vitro activating TNFR1 and further promote rat marrow endothelial progenitor cells (EPCs) apoptosis. Methods: Rat morrow endothelial progenitor cells were cultured and identified by Confocal Microscop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c91a1f4a87904d08471f28671b18f0a5
https://pubmed.ncbi.nlm.nih.gov/26884909

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[Role of Rac1 activation in platelet derived growth factor-BB induced proliferation and migration in rat aortic smooth muscle cells]

Autor: Yong, Liu, Yan-zheng, He, Wen, Li, Sen, Shi, Zi-lun, Li, De-yuan, Zhang, Shen-ming, Wang

Publikováno v: Zhonghua yi xue za zhi. 91(39)

To explore the impact of Rac1 activation on the proliferation and migration under the stimulation of PDGF-BB (platelet derived growth factor-BB).The inhibitory effects of Rac1 inhibitor (NSC23766) and Rac1siRNA on the proliferation and migration of v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02bba7c440a29f6c351d66f4587ef7db
https://pubmed.ncbi.nlm.nih.gov/22322064

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[Non-apoptotic, non-necrotic death of neutrophils induced by EP3 agonist--ONO-AE-248]

Autor: Jia-jia, Liu, Zi, Zhang, Hao, He, Xin, Li, Yan-zheng, He

Publikováno v: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 21(5)

To investigate the effect of EP(3) agonist--ONO-AE-248 on neutrophils.Electron microscopy, MTS assay, RT-PCR and FACS were used to observe the morphology, viability, EP(3) receptor expression and apoptosis of neutrophils treated with ONO-AE-248.EP(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::701bde7534a390a5b0c648ea255001e1
https://pubmed.ncbi.nlm.nih.gov/16143052

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[Revascularization of limb blood supply by arterialization of vein in extensive arterial oblitery ischemia]

Autor: Yan-zheng, He, Hong, Zheng, Wu, Zhong

Publikováno v: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 16(6)

To investigate the effect of arterilization of veins in treatment of extensive arterial oblitery ischemia of limbs.Eighteen lower limbs and six upper limbs with symptoms of chronic ischemia were diagnosed as having extensive occlusion of the major ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f6d7135f89ab70257e064289c9972ca
https://pubmed.ncbi.nlm.nih.gov/12508424

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