Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yan-Yu Cai"'
Autor:
Zi-Jing Li, William Pat Fong, Dong-Sheng Zhang, Hui-Yan Luo, Dong-Liang Chen, Yan-Yu Cai, Zhi-Gang Chen, Jian-Li Duan, Zi-Yao Huang, Yu-Ting Lu, Xiao-Xia Huang, Yu-Hong Li, De-Shen Wang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Anaplastic lymphoma kinase (ALK) fusion-positive colorectal cancer (CRC) is a rare and chemotherapy-refractory subtype that lacks established and effective treatment strategies. Additionally, the efficacy and safety of ALK inhibitors (ALKi)
Externí odkaz:
https://doaj.org/article/bbdc714779f84f3980277043828d8a35
Autor:
Zhi-Gang Chen, Xiao-Meng Ji, Yu-Xia Xu, William Pat Fong, Xiao-Yun Liu, Jie-Ying Liang, Qiong Tan, Lei Wen, Yan-Yu Cai, De-Shen Wang, Yu-Hong Li
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Patients with initially unresectable colorectal cancer liver metastases (IU-CRLM) might benefit from using an effective systemic treatment followed by resection of liver metastases but the curative success rate is quite low. Indeed, nearl
Externí odkaz:
https://doaj.org/article/ccaf6294ee4a4f3d94a0190ab3a31533
Autor:
Zi-Yao Huang, Lei Wen, Liu-Fang Ye, Yu-Ting Lu, William Pat Fong, Ren-Jing Zhang, Si-Xian Wu, Zhi-Gang Chen, Yan-Yu Cai, Rui-Hua Xu, Yu-Hong Li, Zi-Ming Du, De-Shen Wang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Transmembrane E3 ubiquitin ligase ( RNF43 ) mutations are present in approximately 6–18% of colorectal cancers (CRC) and could enhance Wnt/β-catenin signaling, which is emerging as a promising therapeutic target. This study aims to inv
Externí odkaz:
https://doaj.org/article/d267fbf1f23c40f6a8146f578616f919
Autor:
Yun Wang, Fang Hu, Jin-yuan Li, Run-cong Nie, Si-liang Chen, Yan-yu Cai, Ling-ling Shu, De-jun Deng, Jing-bo Xu, Yang Liang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Acute myelogenous leukemia (AML) is a heterogeneous disease with recurrent gene mutations and variations in disease-associated gene expression, which may be useful for prognostic prediction.Methods: RNA matrix and clinical data of AML wer
Externí odkaz:
https://doaj.org/article/dcecaf9505124d6dad51052b4e218c09
Autor:
Run-Cong Nie, Jinyuan Li, Pei-dong Chi, Qian-yi Zhang, Tobias Herold, Wolfgang Hiddemann, Yun Wang, Yong-qing Wang, Xiong Zhang, Yan-Yu Cai, Yu Zhang, Ze-lin Liu, Yang Liang, San-bin Wang, Robert Peter Gale, Yong-zhong Su, Xin Du, Klaus H. Metzeler, Tong-hua Yang, Qing Zhang, Zhe-Yuan Qin, Yun Zeng, Xin-mei Zhang, Yuan-bin Wu, Na Zhong, Jian-wei Wu, Bei Zhang, Zhi-jun Wuxiao, Xue-Yi Pan, Qifa Liu, Zhi-wei Liang, Shun-Qing Wang, Jing-bo Xu, Si-Liang Chen, Bingyi Wu, Ruo-zhi Xiao
Publikováno v:
Clinical Cancer Research. 27:255-266
Purpose: Prediction models for acute myeloid leukemia (AML) are useful, but have considerable inaccuracy and imprecision. No current model includes covariates related to immune cells in the AML microenvironment. Here, an immune risk score was explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766c419714e8ad125b721c145ac1b2ec
https://doi.org/10.1158/1078-0432.ccr-20-3417
https://doi.org/10.1158/1078-0432.ccr-20-3417
Autor:
Yuan Fang Li, Zhiwei Zhou, Run Cong Nie, Guo Ming Chen, Yan Yu Cai, Yun Wang, Shi Chen, Yingbo Chen, Shu Man Li, Shu Qiang Yuan, Jie Zhou, Tian Qi Luo
Publikováno v:
Aging (Albany NY)
This study aimed to construct immune-related predictors to identify responders to anti-PD1 therapy of melanoma through CIBERSORT algorithm. Using the least absolute shrinkage and selection operator (LASSO) logistic regression, we constructed an immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897bed32fc8875d5e2711787a71e7071
https://doi.org/10.18632/aging.102556
https://doi.org/10.18632/aging.102556
Autor:
Yun Wang, Si-Liang Chen, Weida Wang, Run-Cong Nie, Zhe-Yuan Qin, Yu-Jun Dai, Yang Liang, Yan-Yu Cai, Fang Hu
Publikováno v:
Blood. 134:708-708
Background: The present prognosis for AML mainly rely on the cyto- and molecular genetic features. However, the bone marrow microenvironment also plays a critical role in the development and progression of the disease, and the immune signature within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c68f6116883d92b4edbc53581125b365
https://doi.org/10.1182/blood-2019-126733
https://doi.org/10.1182/blood-2019-126733