Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yan-Xing Han"'
Autor:
Tong-Tong Liu, Hai-Fei Sun, Ming-Ze Tang, Hao-Ran Shen, Zhen Shen, Yan-Xing Han, Yun Zhan, Jian-Dong Jiang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Silicosis is an irreversible fibrotic disease of the lung caused by chronic exposure to silica dust, which manifests as infiltration of inflammatory cells, excessive secretion of pro-inflammatory cytokines, and pulmonary diffuse f
Externí odkaz:
https://doaj.org/article/2b118b10efc04e819d2449e7e07a98e0
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Silicosis is a chronic illness marked by diffuse fibrosis in lung tissue resulting from continuous exposure to SiO2-rich dust in the workplace. The onset and progression of silicosis is a complicated and poorly understood pathological process involvi
Externí odkaz:
https://doaj.org/article/8066f3ee7b074408b931c433f1810875
Autor:
Zhen Shen, Yun-Dan Guo, Ming-Ze Tang, Ping Zhou, Yu-Xin Su, Hao-Ran Shen, Tao Li, Wei Jiang, Yan-Xing Han, Cai Tie, Jing-Jing Cui, Tian-Le Gao, Jian-Dong Jiang
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 803 (2024)
Pregabalin is a medication primarily used in the treatment of neuropathic pain and anxiety disorders, owing to its gabapentinoid properties. Pregabalin monotherapy faces limitations due to its variable efficacy and dose-dependent adverse reactions. I
Externí odkaz:
https://doaj.org/article/9febe5dd4fbf4ef28cdd72c6afec79b9
Autor:
Hao-Ran Shen, Zhi-Yu Wang, Zhen Shen, Tong-Tong Liu, Yun-Dan Guo, Tian-Le Gao, Hui-Hui Guo, Yan-Xing Han, Jian-Dong Jiang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115916- (2023)
Silybin (SIL) is a versatile bioactive compound used for improving liver damage and lipid disorders and is also thought to be beneficial for atherosclerosis (AS). The goal of this study was to investigate the efficacy of SIL in the treatment of AS in
Externí odkaz:
https://doaj.org/article/51fcb4fed1dd469c8eeafcfdced4d4fe
Autor:
Gang Ren, Jiang-Hong Guo, Chen-Lin Feng, Yu-Wei Ding, Biao Dong, Yan-Xing Han, Yu-Huan Li, Lu-Lu Wang, Jian-Dong Jiang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 372-386 (2022)
Chemoprevention of hepatocellular carcinoma (HCC) is highly desirable in clinic. Berberine (BBR) is reported to play potential roles in cancer treatment and prevention. We studied the chemopreventive effect of BBR on hepatocellular carcinogenesis in
Externí odkaz:
https://doaj.org/article/eed9698a1e754c0293010ad3f19ecc32
Autor:
Hui-Hui Guo, Hao-Ran Shen, Lu-Lu Wang, Zhi-Gang Luo, Jin-Lan Zhang, Hong-Juan Zhang, Tian-Le Gao, Yan-Xing Han, Jian-Dong Jiang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114754- (2023)
Metformin (MTF) and berberine (BBR) share several therapeutic benefits in treating metabolic-related disorders. However, as the two agents have very different chemical structure and bioavailability in oral route, the goal of this study is to learn th
Externí odkaz:
https://doaj.org/article/8757c3aefdc24bb1bc0d36c047baa1f0
Autor:
Hui-Hui Guo, Chen-Lin Feng, Wen-Xuan Zhang, Zhi-Gang Luo, Hong-Juan Zhang, Ting-Ting Zhang, Chen Ma, Yun Zhan, Rui Li, Song Wu, Zeper Abliz, Cong Li, Xiao-Lin Li, Xiao-Lei Ma, Lu-Lu Wang, Wen-Sheng Zheng, Yan-Xing Han, Jian-Dong Jiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Berberine has lipid-lowering effects and other metabolic benefits, but it presents with poor bioavailability. Here the authors conjugate berberine to liver-targeting nanoparticles, and show increased accumulation of berberine in the liver, improved m
Externí odkaz:
https://doaj.org/article/f1dbe28cac9f4edfac9a5a63a81b496e
Autor:
Chen-Lin Feng, Yan-Xing Han, Hui-Hui Guo, Xiao-Lei Ma, Zhi-Qiang Wang, Lu-Lu Wang, Wen-Sheng Zheng, Jian-Dong Jiang
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1537-1548 (2017)
Our previous work proved that sequence specific double strand RNA (dsRNA-p21) effectively activated p21 gene expression of colorectal cancer (CRC) cells and consequently suppressed CRC growth. However, efficient delivery system is a significant chall
Externí odkaz:
https://doaj.org/article/d9793886ed8647cdb4cce097acea9642
Autor:
Xing-yue Ji, Si-tu Xue, Guang-hui Zheng, Yan-xing Han, Zong-ying Liu, Jian-dong Jiang, Zhuo-rong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 2, Pp 93-99 (2011)
Cajanine, a constituent of Cajanaus cajan L., used in traditional Chinese medicine, is a promising drug candidate because of its broad range of bioactivities. However, the total synthesis of cajanine and its derivatives has never been reported. Herei
Externí odkaz:
https://doaj.org/article/5b16e9040a794db1b26d89d120a89b9d
Autor:
Hui-Hui Guo, Hao-Ran Shen, Ming-Ze Tang, Ning Sheng, Xiao Ding, Yuan Lin, Jin-Lan Zhang, Jian-Dong Jiang, Tian-Le Gao, Lu-Lu Wang, Yan-Xing Han
Publikováno v:
Journal of Ethnopharmacology. 306:116158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d872063f47f7a5d0e2c8ae1d0b733352
https://doi.org/10.1016/j.jep.2023.116158
https://doi.org/10.1016/j.jep.2023.116158