Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yan-Shi Guo"'
Autor:
Ye, Jin-Hai, Xu, Yuan-Jin, Gao, Jun, Yan, Shi-Guo, Zhao, Jun, Tu, Qisheng, Zhang, Jin, Duan, Xue-Jing, Sommer, Cesar A., Mostoslavsky, Gustavo, Kaplan, David L., Wu, Yu-Nong, Zhang, Chen-Ping, Wang, Lin, Chen, Jake
Publikováno v:
In Biomaterials 2011 32(22):5065-5076
Publikováno v:
Digestive Diseases and Sciences. 53:2045-2052
Overexpression of cyclooxygenase-2 (COX-2), an inducible enzyme regulating prostaglandin release, is mechanistically linked to the development, growth, and spread of gastrointestinal (GI) cancers. GI peptide bombesin (BBS) was reported to stimulate C
Autor:
Ji Zhong Cheng, Mark R. Hellmich, Gui Fang Jin, Courtney M. Townsend, J. Silvio Gutkind, Yan Shi Guo
Publikováno v:
Journal of Biological Chemistry. 277:48755-48763
Gastrin is a hormone produced by G-cells in the normal gastric antrum. However, colorectal carcinoma cells may aberrantly produce gastrin and exhibit increased expression of cholecystokinin B (CCK-B)/gastrin receptors. Gastrin is trophic for the norm
Publikováno v:
Journal of Cellular Physiology. 175:141-148
Insulin-like growth factor-I (IGF-I) is known as a potent mitogen for a variety of cell types, including colon cancer cell lines. The objective of this study was to determine the effect of IGF-I on cell death induced by cytotoxic agents actinomycin D
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 268:E1199-E1204
The purposes of this study were to determine the regulation of insulin-like growth factor binding protein-2 (IGFBP-2) in IEC-6 cells by transforming growth factor-beta 1 (TGF-beta 1) and insulin and to determine whether IGFBP-2 mediated the growth-in
Autor:
Yan-Shi, Guo
Publikováno v:
Sheng li ke xue jin zhan [Progress in physiology]. 42(3)
Seventy-five years after its initial report, lifespan prolongation by caloric restriction (CR) has been confirmed in many animal species. Gathered evidences suggest that the histone deacetylase Sir2/SIRT1 is a key mediator. Moreover, resveratrol (RSV
Publikováno v:
Regulatory Peptides. 49:125-131
Polymorphonuclear neutrophils (PMNs) were isolated from human blood, and PMN phagocytosis was assessed by measuring the chemiluminescence (CL) response in the presence of ZAP (opsonized zymosin particles containing luminol). The administration of 6.5
Publikováno v:
Gastroenterology. 104:1595-1604
Background: This study determined whether the resistance to the mitogenic effect of insulinlike growth factor 1 (IGF-1) in AGS (we found that IGF-1 had almost no effect on the growth of AGS) cells is caused by the absence of IGF-1 receptor on the cel
Publikováno v:
Regulatory Peptides. 40:75-86
Several bombesin-receptor antagonists are available that inhibit secretory and growth effects of bombesin, in vitro. In the present study, we examined the effects of a new class of bombesin receptor antagonists (modified GRP(15-27) peptides, with D-P
Publikováno v:
Gastroenterology. 102:1101-1108
A possible role of insulinlike growth factor I (IGF-I) and IGF-I receptors in the proliferation of human colon cancer has, to the best of the authors' knowledge, not been examined as yet. To determine a role of IGF-I in colon cancer, several human co