Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yan-Qing Guan"'
Autor:
Tao Lin, Dandan Chen, Yan Geng, Jiayu Li, Yanghui Ou, Zhijun Zeng, Canqiang Yin, Xudong Qian, Xiang Qiu, Gang Li, Yali Zhang, Wen Guan, Mengjie Li, Xiaojia Cai, Jiaqiang Wu, Wen-Hua Chen, Yan-Qing Guan, Hongliang Yao
Publikováno v:
Gels, Vol 9, Iss 8, p 659 (2023)
Oral ulcer is a common inflammatory disease of oral mucosa, causing severe burning pain and great inconvenience to daily life. In this study, compound 3J with anti-inflammatory activity was synthesized beforehand. Following that, an intelligent compo
Externí odkaz:
https://doaj.org/article/45ae3a4cef5e4b38a78e63ceff67517e
Publikováno v:
International Journal of Biological Macromolecules. 202:296-308
Compared with injection, oral drug delivery is a better mode of administration because of its security, low pain and simplicity. Insulin is the first choice for clinical treatment of type 1 diabetes, but, because insulin inability to resist gastroint
Autor:
Xiaozhen Wang, Jiecheng He, Siyuan Jiang, Yifei Gao, Ling-Kun Zhang, Liang Yin, Rong You, Yan-Qing Guan
Publikováno v:
Journal of Materials Chemistry B. 10:418-429
Tumor heterogeneity is a large challenge to overcome in breast cancer therapy. In this study, we develop one multi-targeted drug delivery system, which could target to BT-474, MCF-7, EMT-6, and MDA-MB-231 cells, and inhibit their growth.
Autor:
Yifei Gao, Yuxue Cheng, Jiapeng Chen, Danmin Lin, Chao Liu, Ling‐Kun Zhang, Liang Yin, Runcai Yang, Yan‐Qing Guan
Publikováno v:
Advanced healthcare materials. 11(23)
The blood-brain barrier (BBB) is a major limiting factor that prevents the treatment of Parkinson's disease (PD). In the present study, MgOp@PPLP nanoparticles are explored by using MgO nanoparticles as a substrate, polydopamine as a shell, wrapping
Autor:
Mingze Xu, Han Qin, Yuxin Zheng, Jiapeng Chen, Xuanxi Liang, Jinpeng Huang, Wenfeng Luo, Runcai Yang, Yan-Qing Guan
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 220
The use of intelligent insulin delivery systems has become more important for treating diabetes. In this study, a dual-responsive oral insulin delivery nanocarrier that responds to glucose and pH has been developed. First, the oleic acid hydrophobic
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 349
Breast cancer has consistently had the highest incidence among women in the world. Tumor cell-derived extracellular vesicles (EV) have been leveraged as drug carriers for cancer treatment. Herein, we developed an efficient theranostic platform for br
Autor:
Shu-Yi Huang, Zhong-Si-Wei Dong, Zhao-Hui Chen, Zhi-Wei Zeng, Wen-Qiao Zhao, Yan-Qing Guan, Chu-Hua Li
Publikováno v:
European journal of pharmacology. 922
Parkinson's disease (PD) always causes dyskinesia and cognitive impairments. The alpha-synuclein (α-syn) accumulation, one of the main pathological characteristics of PD, may impair synaptic structural and synaptic functions. Nano-MgO composites has
Autor:
Lan-Qing Wang, Li Liu, Yan-Qing Guan, Liang Yin, Jinpeng Huang, Wuya Chen, Yi Zhang, Qing Ban, Rong You, Bo Yang
Publikováno v:
Journal of Materials Chemistry B. 8:558-567
The use of bone tissue engineering scaffolds has become a promising potential treatment for bone defects as they expedite bone healing. A carbon nanotube-hydroxyapatite (CNT-HA) composite can accelerate the growth of cells. However, the molecular org
Autor:
Xiaozhen, Wang, Jiecheng, He, Siyuan, Jiang, Yifei, Gao, Ling-Kun, Zhang, Liang, Yin, Rong, You, Yan-Qing, Guan
Publikováno v:
Journal of materials chemistry. B. 10(3)
Breast cancer is one of the most common cancers in the world with tumor heterogeneity. Currently, cancer treatment mainly relies on surgical intervention, chemotherapy, and radiotherapy, for which the side effects, drug resistance and cost need to be
Bacterial cellulose based composites enhanced transdermal drug targeting for breast cancer treatment
Publikováno v:
Chemical Engineering Journal. 370:749-759
Nanotherapies combined with stimuli-triggered activated agents have become attractive ways to traditional chemotherapy. The Fe3O4 nanoparticles was employed as the core coated firstly with hydrogels of dually loaded both doxorubicin and hematoporphyr