Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yan-Qin Shen"'
Autor:
Mei-Xuan Zhang, Hui Hong, Yun Shi, Wen-Yan Huang, Yi-Meng Xia, Lu-Lu Tan, Wei-Jiang Zhao, Chen-Meng Qiao, Jian Wu, Li-Ping Zhao, Shu-Bing Huang, Xue-Bing Jia, Yan-Qin Shen, Chun Cui
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 300 (2024)
Parkinson’s disease (PD) is characterized not only by motor symptoms but also by non-motor dysfunctions, such as olfactory impairment; the cause is not fully understood. Our study suggests that neuronal loss and inflammation in brain regions along
Externí odkaz:
https://doaj.org/article/b97a6b45c17c450a817bf7274fd593d1
Autor:
Chen-Meng Qiao, Wen-Yan Huang, Yu Zhou, Wei Quan, Gu-Yu Niu, Ting Li, Mei-Xuan Zhang, Jian Wu, Li-Ping Zhao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 238 (2024)
Increasing evidence suggests that the gut microbiota may represent potential strategies for Parkinson’s disease (PD) treatment. Our previous research revealed a decreased abundance of Akkermansia muciniphila (Akk) in PD mice; however, whether Akk i
Externí odkaz:
https://doaj.org/article/770f2fcdb0064653b87c47e0372a4742
Autor:
Li-Ping Zhao, Jian Wu, Wei Quan, Yu Zhou, Hui Hong, Gu-Yu Niu, Ting Li, Shu-Bing Huang, Chen-Meng Qiao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Accumulative studies suggest that inflammatory bowel disease (IBD) may cause multiple central nervous system (CNS) pathologies. Studies have found that indoleamine-2,3-dioxygenase (IDO, rate-limiting enzyme of the kynurenine (Kyn) pathway) deficient
Externí odkaz:
https://doaj.org/article/5f29231e6cb143bebf7ecd53f2cd091b
Autor:
Xin-yu Qiao, Yi Wang, Wei Zhang, Qian Li, Chong Liu, Ji-ji Dao, Chen-meng Qiao, Chun Cui, Yan-qin Shen, Wei-jiang Zhao
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 96 (2023)
Objective: Few studies have reported the direct effect of C–X–C motif chemokine ligand 10 (CXCL10) and Neuregulin 1 (Nrg1) on neurons after spinal cord injury (SCI). This study reports the role of CXCL10 in the regulation of neuronal damage after
Externí odkaz:
https://doaj.org/article/457bfb7a80d64776844c23eb4bce8c8e
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundTransient receptor potential melastatin 8 (TRPM8) modulates tumor biology and sensitivity to treatment. The present study aimed to determine the part it plays in tumor immunity and physiology using pan-cancer analysis.MethodData from the GT
Externí odkaz:
https://doaj.org/article/a90d9dd09c184c3b9596d909f1b246e1
Autor:
Wei Quan, Chen-Meng Qiao, Gu-Yu Niu, Jian Wu, Li-Ping Zhao, Chun Cui, Wei-Jiang Zhao, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 790 (2023)
Observational studies have shown abnormal changes in trimethylamine N-oxide (TMAO) levels in the peripheral circulatory system of Parkinson’s disease (PD) patients. TMAO is a gut microbiota metabolite that can cross the blood–brain barrier and is
Externí odkaz:
https://doaj.org/article/960e3ffb27584aa4960d43ae4274541c
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95098 (2014)
Unlike mammals, adult zebrafish are capable of regenerating severed axons and regaining locomotor function after spinal cord injury. A key factor for this regenerative capacity is the innate ability of neurons to re-express growth-associated genes an
Externí odkaz:
https://doaj.org/article/9c85e030fe614031a3f86dd9d7838aae
Autor:
Yan Wang, Gabriele Loers, Hong-Chao Pan, Ricardo Gouveia, Wei-Jiang Zhao, Yan-Qin Shen, Ralf Kleene, Julia Costa, Melitta Schachner
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52404 (2012)
The neural cell adhesion molecule L1 plays important roles in neuronal migration and survival, neuritogenesis and synaptogenesis. L1 has also been found in tumors of different origins, with levels of L1 expression correlating positively with the meta
Externí odkaz:
https://doaj.org/article/128a11e071174f6a9dd45fc4faecb2ba
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52376 (2012)
The cell neural adhesion molecule contactin-2 plays a key role in axon extension and guidance, fasciculation, and myelination during development. We thus asked, whether contactin-2 is also important in nervous system regeneration after trauma. In thi
Externí odkaz:
https://doaj.org/article/c963334227634dec91842ccf7142eb08
Publikováno v:
Fish Physiology and Biochemistry. 47:2041-2053
Intestinal flora is closely related to the health of organisms and the occurrence and development of diseases. The study of intestinal flora will provide a reference for the research and treatment of disease pathogenesis. Upon hatching, fish begin to