Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yan-Jun Pang"'
Autor:
Yu Zhu, Gui-Hua Lu, Zhuo-Wu Bian, Feng-Yao Wu, Yan-Jun Pang, Xiao-Ming Wang, Rong-Wu Yang, Cheng-Yi Tang, Jin-Liang Qi, Yong-Hua Yang
Publikováno v:
BMC Plant Biology, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Shikonin is a naphthoquinone secondary metabolite with important medicinal value and is found in Lithospermum erythrorhizon. Considering the limited knowledge on the membrane transport mechanism of shikonin, this study investigate
Externí odkaz:
https://doaj.org/article/350cfe59397a4d1ca1a08c212f7c38cb
Autor:
Han-Yue Qiu, Xiang Zhu, Yue-Lin Luo, Hong-Yan Lin, Cheng-Yi Tang, Jin-Liang Qi, Yan-Jun Pang, Rong-Wu Yang, Gui-Hua Lu, Xiao-Ming Wang, Yong-Hua Yang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Signal transducer and activator of transcription 3 (STAT3) is hyper-activated in diversiform human tumors and has been validated as an attractive therapeutic target. Current research showed that a natural product, shikonin, along with its sy
Externí odkaz:
https://doaj.org/article/aff6189e0a284adcb62ed7e81cccab4e
Autor:
Feng-Yao Wu, Cheng-Yi Tang, Yu-Min Guo, Zhuo-Wu Bian, Jiang-Yan Fu, Gui-Hua Lu, Jin-Liang Qi, Yan-Jun Pang, Yong-Hua Yang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Shikonin and its derivatives extracted from Lithospermeae plants’ red roots have current applications in food and pharmaceutical industries. Previous studies have cloned some genes related to shikonin biosynthesis. However, most genes rela
Externí odkaz:
https://doaj.org/article/62f975e5c56442998aa746c2e5e2079d
Autor:
Bao Liu, Minkai Yang, Rongjun Fang, Aliya Fazal, Yong-Hua Yang, Hua Zhao, Tongming Yin, Yan-Jun Pang, Gui-Hua Lu, Jiangyan Fu, Zhongling Wen, Jia-Xin Bao, Jin-Liang Qi
Publikováno v:
3 Biotech. 10
Echium plantagineum L. (Boraginaceae) is an invasive species in Australia and contains medicinal shikonins in its roots. In this study, the hairy root lines of E. plantagineum were established using Agrobacterium rhizogenes strain ATCC15834 and confi
Autor:
Jiang-Yan, Fu, Hua, Zhao, Jia-Xin, Bao, Zhong-Ling, Wen, Rong-Jun, Fang, Aliya, Fazal, Min-Kai, Yang, Bao, Liu, Tong-Ming, Yin, Yan-Jun, Pang, Gui-Hua, Lu, Jin-Liang, Qi, Yong-Hua, Yang
Publikováno v:
3 Biotech
Echium plantagineum L. (Boraginaceae) is an invasive species in Australia and contains medicinal shikonins in its roots. In this study, the hairy root lines of E. plantagineum were established using Agrobacterium rhizogenes strain ATCC15834 and confi
Autor:
Xiao-Mei Hua, Jin-Liang Qi, Yong-Hua Yang, Yehao Liu, Karin Müller, Tongyi Yang, Hailong Wang, Xin Peng, Yongchun Li, Yan-Jun Pang, Qiong Wang, Meng-Cheng Wang
Publikováno v:
Environmental Science and Pollution Research. 25:14762-14772
Glyphosate is a non-selective organophosphate herbicide that is widely used in agriculture, but its effects on soil microbial communities are highly variable and often contradictory, especially for high dose applications. We applied glyphosate at two
Autor:
Wu Xun, Rong-Wu Yang, Cui Hu, Yan-Jun Pang, Xiang Zhu, Jin-Liang Qi, Gu-Hao Wang, Yong-Hua Yang, Gui-Hua Lu, Xiao-Ming Wang, Hong-Wei Han
Publikováno v:
Medicinal Chemistry Research. 27:351-365
A series of podophyllotoxin derivatives (M1–M16) that were selectively acylated by various phenoxy acids at the C-4 position of podophyllotoxin were synthesized, and their biological activities were also evaluated. Among them, compound M4 showed th
Autor:
Cheng-Yi Tang, Ling-Ru Kong, Yong-Hua Yang, Rong-Wu Yang, Xiao-Mei Hua, Yin-Ling Zhu, Jin-Liang Qi, Yan-Jun Pang, Jing Cheng, Gui-Hua Lu, Fan-Fan Meng
Publikováno v:
Journal of Microbiology and Biotechnology. 27:561-572
The global commercial cultivation of transgenic crops, including glyphosate-tolerant soybean, has increased widely in recent decades with potential impact on the environment. The bulk of previous studies showed different results on the effects of the
Autor:
Fu-Gen Yu, Han-Yue Qiu, Wen-Xue Sun, Z.H. Wang, Yan-Jun Pang, Jin-Liang Qi, Yong-Hua Yang, Gui-Hua Lu, Xiao-Ming Wang, Ya-Han Zhang, Xue Wang
Publikováno v:
Chemical Biology & Drug Design. 90:236-243
The advancement of cancer-fighting drugs has never been a simple linear process. Those drug design professionals begin to find inspiration from the nature after failing to find the ideal products by creative drug design and high-throughput screening.
Autor:
Rong-Wu Yang, Han-Yue Qiu, Jin-Liang Qi, Yan-Jun Pang, Gui-Hua Lu, Fang Wang, Wen-Xue Sun, Yong-Hua Yang, Xiao-Ming Wang, Xue Wang
Publikováno v:
ChemMedChem. 12:399-406
The biological importance of microtubules in mitosis makes them an interesting target for the development of anticancer agents. In this study, a series of novel chalcone-containing shikonin derivatives was designed, synthesized, and evaluated for bio