Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Yan-Bing ZHANG"'
Autor:
Jin-Bo Niu, Chun-Hua Quan, Yuan Liu, Guang-Xi Yu, Jia-Jia Yang, Yin-Ru Li, Yan-Bing Zhang, Ying-Qiu Qi, Jian Song, Cheng-Yun Jin, Sai-Yang Zhang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1715-1731 (2021)
Hippo signalling pathway plays a crucial role in tumorigenesis and cancer progression. In this work, we identified an N-aryl sulphonamide-quinazoline derivative, compound 9i as an anti-gastric cancer agent, which exhibited potent antiproliferative ab
Externí odkaz:
https://doaj.org/article/8ef17c5ecd874c5ebebd48e3d50c3f93
Autor:
Yi-Chao Shi, Shun-Tian Cai, Ya-Ping Tian, Hui-Jun Zhao, Yan-Bing Zhang, Jing Chen, Rong-Rong Ren, Xi Luo, Li-Hua Peng, Gang Sun, Yun-Sheng Yang
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 1, Pp 52-63 (2019)
Proton pump inhibitors (PPIs) are commonly used to lessen symptoms in patients with gastroesophageal reflux disease (GERD). However, the effects of PPI therapy on the gastrointestinal microbiota in GERD patients remain unclear. We examined the associ
Externí odkaz:
https://doaj.org/article/7a4120866c7e4dec8e19a020dd08e74e
Publikováno v:
Journal of Food Quality, Vol 2020 (2020)
The purpose of the present work was to evaluate the inhibitory effects of different phenolic extracts from non- and ultra-high-pressure- (UHP-) treated palm fruits and their main phenolic compounds against pancreatic lipase and α-glucosidase and to
Externí odkaz:
https://doaj.org/article/e08f69953506403ab1fd054e14e60a31
Autor:
Yong-Feng Guan, Xiu-Juan Liu, Xin-Ying Yuan, Wen-Bo Liu, Yin-Ru Li, Guang-Xi Yu, Xin-Yi Tian, Yan-Bing Zhang, Jian Song, Wen Li, Sai-Yang Zhang
Publikováno v:
Molecules, Vol 26, Iss 16, p 4899 (2021)
The chalcone and quinoline scaffolds are frequently utilized to design novel anticancer agents. As the continuation of our work on effective anticancer agents, we assumed that linking chalcone fragment to the quinoline scaffold through the principle
Externí odkaz:
https://doaj.org/article/30cc84c1a9ea4e4ba893f04855a086f2
Autor:
Xu Liu, Xiao-Jing Pang, Yuan Liu, Wen-Bo Liu, Yin-Ru Li, Guang-Xi Yu, Yan-Bing Zhang, Jian Song, Sai-Yang Zhang
Publikováno v:
Molecules, Vol 26, Iss 13, p 4047 (2021)
Tubulin has been regarded as an attractive and successful molecular target in cancer therapy and drug discovery. Vicinal diaryl is a simple scaffold found in many colchicine site tubulin inhibitors, which is also an important pharmacophoric point of
Externí odkaz:
https://doaj.org/article/dab30dc0e5ca44a2b3e3d4a153556412
Autor:
Xiao-Jing Pang, Xiu-Juan Liu, Yuan Liu, Wen-Bo Liu, Yin-Ru Li, Guang-Xi Yu, Xin-Yi Tian, Yan-Bing Zhang, Jian Song, Cheng-Yun Jin, Sai-Yang Zhang
Publikováno v:
Molecules, Vol 26, Iss 14, p 4250 (2021)
FAK is a nonreceptor intracellular tyrosine kinase which plays an important biological function. Many studies have found that FAK is overexpressed in many human cancer cell lines, which promotes tumor cell growth by controlling cell adhesion, migrati
Externí odkaz:
https://doaj.org/article/57aac87141774f78808ca2a8f94f0955
Autor:
Chao-Fan Lu, Sheng-Hui Wang, Xiao-Jing Pang, Ting Zhu, Hong-Li Li, Qing-Rong Li, Qian-Yu Li, Yu-Fan Gu, Zhao-Yang Mu, Min-Jie Jin, Yin-Ru Li, Yang-Yang Hu, Yan-Bing Zhang, Jian Song, Sai-Yang Zhang
Publikováno v:
Molecules, Vol 25, Iss 23, p 5530 (2020)
Chalcone is a common scaffold found in many biologically active compounds. The chalcone scaffold was also frequently utilized to design novel anticancer agents with potent biological efficacy. Aiming to continue the research of effective chalcone der
Externí odkaz:
https://doaj.org/article/e99955b3d1a64f949f7cdee869c622d4
Publikováno v:
Molecules, Vol 18, Iss 10, Pp 11866-11872 (2013)
Two new monoterpenes, p-mentha-1(7),8-dien-2-O-b-d-glucoside (1) and trans-2,4-dihydroxy-2,4-dimethyl-trans-1-acetic acid g-lactone (2) were isolated from the fruits of Illicium lanceolatum along with trans-2,4-dihydroxy-2,4-dimethyl-cis-1-acetic aci
Externí odkaz:
https://doaj.org/article/9125a6b31e10465ca06f179bdbd57042
Publikováno v:
Molecules, Vol 22, Iss 9, p 1470 (2017)
A series of sulfanilamide-1,2,3-triazole hybrids were designed by a molecular hybridization strategy and evaluated for antiproliferative activity against three selected cancer cell lines (MGC-803, MCF-7 and PC-3). The detailed structure-activity rela
Externí odkaz:
https://doaj.org/article/6522f56becfd477da1f4c166d1d93690
Autor:
JIA Liyan, ZHAO Nengjiang, YAN Bing, ZHANG Zhihai, ZHAN Na, LIN Yuanbing, LIU Jianping, YANG Shuyu
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 05, Pp 589-596 (2024)
Background Primary care physicians (PCPs), who play a crucial role in providing primary healthcare services, utilize clinical practice guidelines as valuable tools for guiding their practice. By investigating these physicians' awareness and usage of
Externí odkaz:
https://doaj.org/article/3fd9433261cc4ccb9e36f65eac0e8b4b