Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Yan Yuan Tseng"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Alpha/beta hydrolase domain-containing protein 5 (ABHD5) is a highly conserved protein that regulates various lipid metabolic pathways via interactions with members of the perilipin (PLIN) and Patatin-like phospholipase domain-containing pro
Externí odkaz:
https://doaj.org/article/07a0113c67754ffb8611eff0c7c09d8a
Autor:
Xiaohua Dai, Devi Thiagarajan, Jingye Fang, Jianbin Shen, Neeraja Priyanka Annam, Zhao Yang, Hong Jiang, Donghong Ju, Youming Xie, Kezhong Zhang, Yan Yuan Tseng, Zhe Yang, Arun K Rishi, Hui J Li, Maozhou Yang, Li Li
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190191 (2017)
Vascular smooth muscle cell (VSMC) phenotypic modulation is characterized by the downregulation of SMC actin cytoskeleton proteins. Our published study shows that depletion of SM22α (aka SM22, Transgelin, an actin cytoskeleton binding protein) promo
Externí odkaz:
https://doaj.org/article/d298d828945647a2849055ef59946154
We report the Structure-based Pathogenicity Relationship Identifier (SPRI), a novel computational tool for accurate evaluation of pathological effects of missense single mutations and prediction of higher-order spatially organized units of mutation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc4d56fd6d038061f19033f06233642
https://doi.org/10.1101/2022.09.27.508720
https://doi.org/10.1101/2022.09.27.508720
Autor:
Wen-Hsiung Li, Chia-Wei Tai, Jinn-Jy Lin, Yu-Ting Chiou, Tz-Fan Shiu, Chi-An Chen, Yan Yuan Tseng, Tian-Neng Li, Chih-Yao Chang, Maloyjo Joyraj Bhattacharjee, Chia-Yi Chou, Lily Hui-Ching Wang, Paromita Chakraborty
Publikováno v:
Molecular Biology and Evolution
SARS-CoV-2 infects humans through the binding of viral S-protein (spike protein) to human angiotensin I converting enzyme 2 (ACE2). The structure of the ACE2-S-protein complex has been deciphered and we focused on the 27 ACE2 residues that bind to S-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7ec6709df726d8fd9a15d785f795e7
https://doi.org/10.1093/molbev/msab060
https://doi.org/10.1093/molbev/msab060
Autor:
Tzu-Hsien Yang, Chia-Wei Hsu, Yan-Xiang Wang, Chien-Hung Yu, Jagat Rathod, Yan-Yuan Tseng, Wei-Sheng Wu
Publikováno v:
Computers in Biology and Medicine. 151:106314
Comparative analysis among multiple gene lists on their functional features is now a routine task due to the advancement of high-throughput experiments. Several enrichment analysis tools were developed in the past. However, these tools mainly focus o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31817d3ba76745d0551ac78bd43b595c
https://doi.org/10.1016/j.compbiomed.2022.106314
https://doi.org/10.1016/j.compbiomed.2022.106314
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-23 (2021)
BMC Bioinformatics
BMC Bioinformatics
Background Piwi-interacting RNAs (piRNAs) are the small non-coding RNAs (ncRNAs) that silence genomic transposable elements. And researchers found out that piRNA also regulates various endogenous transcripts. However, there is no systematic understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1758256cf1aafae37bbe2cb4c62ec2b
https://doi.org/10.1186/s12859-021-04428-6
https://doi.org/10.1186/s12859-021-04428-6
Publikováno v:
IEEE EMBS Int Conf Biomed Health Inform
BHI
BHI
Missense SNPs are key factors contributing towards many Mendelian disorders and complex diseases. Identifying whether a single amino acid substitution will lead to pathological effects is important for interpreting personal genome and for precision m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159f2b7b69657bce7aac9a8cb953e2a1
https://pubmed.ncbi.nlm.nih.gov/34136829
https://pubmed.ncbi.nlm.nih.gov/34136829
Autor:
Wei Sheng Wu, Ya Chiao Yang, Joseph T. Tseng, Yan Yuan Tseng, Kai Chi Tu, Po Heng Lin, Sheng Cian Shiue, Tzu Hsien Yang, Yu Hsuan Chiang
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5149-5159 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5149-5159 (2021)
Transcript isoforms regulated by alternative splicing can substantially impact carcinogenesis, leading to a need to obtain clues for both gene differential expression and malfunctions of isoform distributions in cancer studies. The Cancer Genome Atla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4953cee05c976b73b2b67f27b4f2ec40
https://pubmed.ncbi.nlm.nih.gov/34589189
https://pubmed.ncbi.nlm.nih.gov/34589189
Publikováno v:
Proceedings of the National Academy of Sciences
Significance The nonsynonymous substitutions ( d N )-to-synonymous substitutions ( d S ) ratio in protein-coding genes is commonly used to study the mechanisms of gene evolution. To understand why RNA viruses show large variations in d N / d S , we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2d9a64131b3016e134ead80afb8256
https://doi.org/10.1073/pnas.1907626116
https://doi.org/10.1073/pnas.1907626116
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 22, Iss S10, Pp 1-12 (2021)
BMC Bioinformatics, Vol 22, Iss S10, Pp 1-12 (2021)
Background Translational regulation is one important aspect of gene expression regulation. Dysregulation of translation results in abnormal cell physiology and leads to diseases. Ribosome profiling (RP), also called ribo-seq, is a powerful experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2505283f47f180456439977b4b8f67ed
https://doi.org/10.1186/s12859-021-04192-7
https://doi.org/10.1186/s12859-021-04192-7