Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yan Sergerie"'
Autor:
Lauriane Harrington, Emmanuel Aris, Amit Bhavsar, Nicolas Jamet, Essè Ifèbi Hervé Akpo, Jason C. Simeone, Anna Ramond, Dimitra Lambrelli, John Oppenheimer, Yan Sergerie, Piyali Mukherjee, Kinga Meszaros
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 4, Pp 1103-1118 (2023)
Abstract Introduction Pertussis, a highly infectious respiratory disease caused by Bordetella pertussis, affects people of all ages. Older adults are particularly susceptible to its severe outcomes and complications. Methods In this retrospective coh
Externí odkaz:
https://doaj.org/article/6755484299c4479db181d017d39356cb
Publikováno v:
Infectious Diseases and Therapy. 11:1821-1838
Following the introduction of pertussis vaccination during infancy, the age-related demographics of pertussis epidemiology have changed.To better understand the pertussis burden (defined here as number of cases and/or incidence rate [IR]) among older
Autor:
Yan Sergerie, Lauriane Harrington, Kinga Meszaros, Anna Ramond, Emmanuel Aris, Nicolas Jamet, Piyali Mukherjee, Bhavsar Amit, Akpo Essè Ifèbi Hervé, Dimitra Lambrelli, Jason C Simeone
Publikováno v:
Respiratory infections and bronchiectasis.
Autor:
Brian K. Miles, Kevin C. Yim, Mélanie Martin, Yan Sergerie, Guy Boivin, Julio Canas, Sarah Dambrosi
Publikováno v:
Journal of Medical Virology. 82:1000-1006
Herpes simplex virus (HSV) resistance to acyclovir or foscarnet results from mutations in viral thymidine kinase (TK) and/or DNA polymerase (pol) genes. Replication kinetics and virulence of TK and/or DNA pol clinical mutants were assessed using mode
Publikováno v:
The Journal of Infectious Diseases. 198:664-672
Background. We evaluated the effect of pretreatment with Toll-like receptor (TLR) agonists in a mouse model of herpes simplex virus type 1 (HSV-1) encephalitis. Methods. BALB/c mice received a single intraperitoneal or intranasal injection of polyino
Autor:
Yan Sergerie, Guy Boivin
Publikováno v:
Antiviral Research. 77:77-80
Drug-resistant herpes simplex virus type 1 (HSV-1) recombinant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes were evaluated for their susceptibility to various antivirals in the presence of 25 μg/ml of hydroxyur
Publikováno v:
Journal of Clinical Virology. 37:248-251
Background Few studies have performed sequential evaluation of the herpes simplex virus (HSV) load using quantitative PCR during episodes of herpes labialis. Objective To determine HSV viral load kinetics during recurrences of herpes labialis. Study
Publikováno v:
Journal of Clinical Microbiology. 42:2663-2667
Human herpesvirus 8 (HHV-8) has been associated with all types of Kaposi's sarcoma (KS), including posttransplantation KS. However, little is known regarding HHV-8 infections in hematopoietic stem cell transplant (SCT) recipients. In this study, we u
Autor:
Yan Sergerie, Guy Boivin
Publikováno v:
Antimicrobial agents and chemotherapy. 50(11)
Contributions of thymidine kinase (TK) mutations to acyclovir (ACV) resistance were evaluated in herpes simplex virus type 1 recombinant viruses generated using a set of overlapping cosmids and plasmids. Alterations in both conserved and nonconserved
Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR
Autor:
Yan Sergerie, Guy Boivin
Publikováno v:
Journal of clinical microbiology. 41(8)
A new in vitro system based on real-time PCR was developed for evaluation of human herpesvirus 8 susceptibility to antiviral agents. Cidofovir had the greatest inhibitory activity against HHV-8 (50% inhibitory concentration [IC 50 ], 0.43 μM) follow