Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Yan Q, Xiong"'
Autor:
Rajesh Parmar, Harry Pickering, Richard Ahn, Maura Rossetti, David W. Gjertson, Felicia Ruffin, Liana C. Chan, Vance G. Fowler, Michael R. Yeaman, Elaine F. Reed, MRSA Systems Immunology Group, Arnold S. Bayer, Yu-Ling Chang, Scott G. Filler, Vance G. Fowler Jr., David Gjertson, Alexander Hoffmann, Felix Mba Medie, Tsuyoshi Mikkaichi, Simon Mitchell, Yan Qin, Batu K. Sharma-Kuinkel, Katherine Sheu, Joshua Thaden, Alan J. Waring, Yan Q. Xiong, Ying Zheng, Michael R. Yeaman.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionStaphylococcus aureus bacteremia (SAB) is a life-threatening infection particularly involving methicillin-resistant S. aureus (MRSA). In contrast to resolving MRSA bacteremia (RB), persistent MRSA bacteremia (PB) blood cultures remain pos
Externí odkaz:
https://doaj.org/article/a79666f3f3d748269414ccca0d43d820
Autor:
Yi Li, Fengli Zhu, Adhar C. Manna, Liang Chen, Jason Jiang, Jong-In Hong, Richard A. Proctor, Arnold S. Bayer, Ambrose L. Cheung, Yan Q. Xiong
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a serious public health threat. We recently demonstrated that the presence of a novel prophage ϕSA169 was associated with vancomycin (VAN) treat
Externí odkaz:
https://doaj.org/article/2ebfbf0b3c694e2b87c6a3abf8df6716
Autor:
Liana C. Chan, Hong K. Lee, Ling Wang, Siyang Chaili, Yan Q. Xiong, Arnold S. Bayer, Richard A. Proctor, Michael R. Yeaman
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1180 (2023)
Invasive methicillin-resistant Staphylococcus aureus (MRSA) infections are leading causes of morbidity and mortality that are complicated by increasing resistance to conventional antibiotics. Thus, minimizing virulence and enhancing antibiotic effica
Externí odkaz:
https://doaj.org/article/a160510e6a7142b3a32dd3f156556b75
Autor:
Liana C. Chan, Mihyun Park, Hong K. Lee, Siyang Chaili, Yan Q. Xiong, Arnold S. Bayer, Richard A. Proctor, Michael R. Yeaman
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 902 (2023)
Virulence factor expression is integral to pathogenicity of Staphylococcus aureus. We previously demonstrated that aspirin, through its major metabolite, salicylic acid (SAL), modulates S. aureus virulence phenotypes in vitro and in vivo. We compared
Externí odkaz:
https://doaj.org/article/ede63f54fb7e4dcaac5bc879970620ab
Autor:
Liang Li, Yi Li, Fengli Zhu, Ambrose L. Cheung, Genzhu Wang, Guangchun Bai, Richard A. Proctor, Michael R. Yeaman, Arnold S. Bayer, Yan Q. Xiong
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections represent a significant clinically challenging subset of invasive, life-threatening S. aureus infections. We have recently demonstrated that purine biosynt
Externí odkaz:
https://doaj.org/article/1063c77480d04c499e5d906337d3814c
Autor:
Genzhu Wang, Liang Li, Xiukun Wang, Xue Li, Youwen Zhang, Jie Yu, Jiandong Jiang, Xuefu You, Yan Q. Xiong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 6, Pp 1174-1182 (2019)
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection. Staphylococcal accessory regulator A (SarA), a
Externí odkaz:
https://doaj.org/article/2c49a4a2453346aaaa79fbf6d195925a
Autor:
Qing Wang, Yuemeng Lv, Jing Pang, Xue Li, Xi Lu, Xiukun Wang, Xinxin Hu, Tongying Nie, Xinyi Yang, Yan Q. Xiong, Jiandong Jiang, Congran Li, Xuefu You
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 3, Pp 496-504 (2019)
As d-amino acids play important roles in the physiological metabolism of bacteria, combination of d-amino acids with antibiotics may provide synergistic antibacterial activity. The aim of the study was to evaluate in vitro and in vivo activity of d-s
Externí odkaz:
https://doaj.org/article/20b1242d26ea429cb9dc712bf33f2124
Autor:
Liang Li, Genzhu Wang, Yi Li, Patrice Francois, Arnold S. Bayer, Liang Chen, Kati Seidl, Ambrose Cheung, Yan Q. Xiong
Publikováno v:
mSystems, Vol 5, Iss 3 (2020)
ABSTRACT Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections are life-threatening syndromes with few therapeutic options. The potential impact of bacteriophages on the persistent outcome has not been well studied. In
Externí odkaz:
https://doaj.org/article/f31c0d01374d47f69c951c98bddb6864
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination
Externí odkaz:
https://doaj.org/article/fc3085d06ada457fa48656ccd9e95a42
Publikováno v:
Antibiotics, Vol 11, Iss 3, p 316 (2022)
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of life-threatening endovascular infections. Endothelial cell (EC) damage is a key factor in the pathogenesis of these syndromes. However, genetic factors related to the EC damage
Externí odkaz:
https://doaj.org/article/fe699b26df4744588cce443d0f0f0f43