Zobrazeno 1 - 10
of 479
pro vyhledávání: '"Yan Pearlly"'
Autor:
Rodriguez Benjamin AT, Frankhouser David, Murphy Mark, Trimarchi Michael, Tam Hok-Hei, Curfman John, Huang Rita, Chan Michael WY, Lai Hung-Cheng, Parikh Deval, Ball Bryan, Schwind Sebastian, Blum William, Marcucci Guido, Yan Pearlly, Bundschuh Ralf
Publikováno v:
BMC Genomics, Vol 13, Iss Suppl 6, p S14 (2012)
Abstract Background Advances in whole genome profiling have revolutionized the cancer research field, but at the same time have raised new bioinformatics challenges. For next generation sequencing (NGS), these include data storage, computational cost
Externí odkaz:
https://doaj.org/article/b9daefeb4a7e47a598b8b3d2c15b11ba
Autor:
Badr, Asmaa, Daily, Kylene P., Eltobgy, Mostafa, Estfanous, Shady, Tan, Michelle H., Chun-Tien Kuo, Jimmy, Whitham, Owen, Carafice, Cierra, Gupta, Gauruv, Amer, Heba M., Shamseldin, Mohamed M., Yousif, Amir, Deems, Nicholas P., Fitzgerald, Julie, Yan, Pearlly, Webb, Amy, Zhang, Xiaoli, Pietrzak, Maciej, Ghoneim, Hazem E., Dubey, Purnima, Barrientos, Ruth M., Lee, Robert J., Kokiko-Cochran, Olga N., Amer, Amal O.
Publikováno v:
In Brain Behavior and Immunity July 2024 119:919-944
Autor:
Dewal, Revati S., Yang, Felix T., Baer, Lisa A., Vidal, Pablo, Hernandez-Saavedra, Diego, Seculov, Nickolai P., Ghosh, Adhideb, Noé, Falko, Togliatti, Olivia, Hughes, Lexis, DeBari, Megan K., West, Michael D., Soroko, Richard, Sternberg, Hal, Malik, Nafees N., Puchulu-Campanella, Estella, Wang, Huabao, Yan, Pearlly, Wolfrum, Christian, Abbott, Rosalyn D., Stanford, Kristin I.
Publikováno v:
In iScience 16 February 2024 27(2)
Publikováno v:
BioData Mining, Vol 4, Iss 1, p 13 (2011)
Abstract Background DNA methylation plays a very important role in the silencing of tumor suppressor genes in various tumor types. In order to gain a genome-wide understanding of how changes in methylation affect tumor growth, the differential methyl
Externí odkaz:
https://doaj.org/article/70c8d91cd7214e73bb521dada2509008
Autor:
Yan Pearlly S, Chu Pei-Yi, Yeh Kun-Tu, Chen Chien-Min, Sun Wei-Sheng, Hung Yi-Chen, Lai Yen-Ling, Yen Jia-Yi, Kuo Tzen-Yu, Lee Kuan-Der, Tseng Min-Jen, Leu Yu-Wei, Hsu Chia-Chen, Chang Yu-Sun, Huang Tim H-M, Hsiao Shu-Huei
Publikováno v:
Journal of Biomedical Science, Vol 18, Iss 1, p 12 (2011)
Abstract Background The Cdc42-interacting protein-4, Trip10 (also known as CIP4), is a multi-domain adaptor protein involved in diverse cellular processes, which functions in a tissue-specific and cell lineage-specific manner. We previously found tha
Externí odkaz:
https://doaj.org/article/9be26350577b446aba2f099478e9ab76
Publikováno v:
BMC Bioinformatics, Vol 12, Iss 1, p 54 (2011)
Abstract Background DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understanding of the methylation changes that occur in tumors, we have deve
Externí odkaz:
https://doaj.org/article/86497dac658d46519716a9a4d4fe70ce
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 404 (2009)
Abstract Background DNA methylation plays an important role in the process of tumorigenesis. Identifying differentially methylated genes or CpG islands (CGIs) associated with genes between two tumor subtypes is thus an important biological question.
Externí odkaz:
https://doaj.org/article/260b1c0a96b74e6a8d1c9390995951c8
Autor:
Chung Jae, Jeong Mikyoung, Montgomery John S, Balch Curt, Li Meng, Yan Pearlly, Huang Tim HM, Kim Sun, Nephew Kenneth P
Publikováno v:
BMC Medical Genomics, Vol 2, Iss 1, p 34 (2009)
Abstract Background Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, resulting in fully
Externí odkaz:
https://doaj.org/article/1328430432894750a978af725c350a9f
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 453 (2008)
Abstract Background Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions have been observed in differential methylation hybridization (DM
Externí odkaz:
https://doaj.org/article/caa21679e48a455fabfee17184358396
Autor:
Vass J Keith, Yan Pearlly, Huang Tim HM, Zeller Constanze, Graham Janet, Teodoridis Jens M, Dai Wei, Brown Robert, Paul Jim
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 337 (2008)
Abstract Background Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role in tumor development, CpG island methylation contributes to th
Externí odkaz:
https://doaj.org/article/c98df030f7b34c3ea645fb1c69e16177