Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yan Ni Lo"'
99
Endocannabinoid system involves in variety of physiological processes in our body such as appetite, mood and memory. Cannabinoid receptors contain two subtypes, i.e. cannabinoid receptor type 1 (CB1R) and type 2 (CB2R). Brain-enriched CB1R is
Endocannabinoid system involves in variety of physiological processes in our body such as appetite, mood and memory. Cannabinoid receptors contain two subtypes, i.e. cannabinoid receptor type 1 (CB1R) and type 2 (CB2R). Brain-enriched CB1R is
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/05723034989017421601
Autor:
Keng-Chang Tsai, Chao-Di Chang, Ming-Hui Cheng, Tsai-Yu Lin, Yan-Ni Lo, Tz-Wen Yang, Fu-Ling Chang, Chen-Wei Chiang, Yu-Ching Lee, Yun Yen
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2387-2397 (2019)
Externí odkaz:
https://doaj.org/article/674b1639a45e47fe88bffa82339cd5fb
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Effect of MPT0L145 on autophagosome formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eefad100bb3432e801a07749d10661
https://doi.org/10.1158/1078-0432.22465095.v1
https://doi.org/10.1158/1078-0432.22465095.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Supplementary Fig. S1, Time-dependent effects of BGJ398 on autophagy in bladder cancer cells. Supplementary Figure. S2. In vitro inhibitory effects of MPT0L145 and SAR405 on PIK3C3 (VPS34). Supplementary Figure. S3. A and B, The potentiation of MPT0L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658cfe700613ef13276cba7e40fe9540
https://doi.org/10.1158/1078-0432.22465083.v1
https://doi.org/10.1158/1078-0432.22465083.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Supplementary Table S1. In vitro inhibitory effects of MPT0L145 on a panel of lipid kinases. Supplementary Table S2. Binding kinetics and affinity of MPT0L145 to wildtype and mutant PIK3C3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad19c396322093c1f2b0450b86e62cbf
https://doi.org/10.1158/1078-0432.22465086.v1
https://doi.org/10.1158/1078-0432.22465086.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Purpose: MPT0L145 has been developed as a FGFR inhibitor exhibiting significant anti-bladder cancer activity in vitro and in vivo via promoting autophagy-dependent cell death. Here, we aim to elucidate the underlying mechanisms.Experimental Design: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec2bd6c4cab8f6c8a53ed80092dc4ae
https://doi.org/10.1158/1078-0432.c.6525918.v1
https://doi.org/10.1158/1078-0432.c.6525918.v1
Autor:
Keng-Chang Tsai, Tz Wen Yang, Fu Ling Chang, Yan Ni Lo, Chih Tien Chen, Tsai Yu Lin, Yu Ching Lee, Ting Sheng Chung, Wang Chuan Chen, Ming Hui Cheng, Tsung Hsun Tsai
Publikováno v:
Experimental Animals
For highly conserved mammalian protein, chicken is a suitable immune host to generate antibodies. Monoclonal antibodies have been successfully targeted with immunity checkpoint proteins as a means of cancer treatment; this treatment enhances tumor-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c70a0165d0630797cf755102694e0a
http://europepmc.org/articles/PMC8390317
http://europepmc.org/articles/PMC8390317
Autor:
Ming Hui Cheng, Fu Ling Chang, Yu Ching Lee, Chao Di Chang, Tz Wen Yang, Yan Ni Lo, Yun Yen, Keng-Chang Tsai, Tsai Yu Lin, Chen Wei Chiang
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2387-2397 (2019)
Fibroblast growth factors (FGFs) and their receptors control various biological functions. Dysregulated FGF signaling has been implicated in the pathogenesis of human cancers. Aberrant activation o...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e947f645eccc79279e8ae06f164398
https://doi.org/10.1021/acsomega.8b03072
https://doi.org/10.1021/acsomega.8b03072
Autor:
Kai Cheng Hsu, Yu Chen Lin, Hao Ching Wang, Yan Ni Lo, Yun Yen, Chun A. Changou, Cheng Ying Chu, Yu Ching Lee, Chun Han Chen, Jing Ping Liou, Tsung Han Hsieh, Yun Ru Liu
Publikováno v:
Clinical Cancer Research. 24:1176-1189
Purpose: MPT0L145 has been developed as a FGFR inhibitor exhibiting significant anti-bladder cancer activity in vitro and in vivo via promoting autophagy-dependent cell death. Here, we aim to elucidate the underlying mechanisms. Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5b7e34196af1a45cdaafcaeb1a7cc3
https://doi.org/10.1158/1078-0432.ccr-17-2066
https://doi.org/10.1158/1078-0432.ccr-17-2066
Autor:
Tsai-Yu LIN, Tsung-Hsun TSAI, Chih-Tien CHEN, Tz-Wen YANG, Fu-Ling CHANG, Yan-ni LO, Ting-sheng CHUNG, Ming-Hui CHENG, Wang-Chuan CHEN, Keng-Chang TSAI, Yu-Ching LEE
Publikováno v:
Experimental Animals; 2021, Vol. 70 Issue 3, p333-343, 11p