The protective effect of SARS-CoV-2 antibodies in Scottish healthcare workers

Autor: Hani Abo-Leyah, Stephanie Gallant, Diane Cassidy, Yan Hui Giam, Justin Killick, Beth Marshall, Gordon Hay, Caroline Snowdon, Eleanor J. Hothersall, Thomas Pembridge, Rachel Strachan, Natalie Gallant, Benjamin J. Parcell, Jacob George, Elizabeth Furrie, James D. Chalmers

Publikováno v: ERJ Open Research, Vol 7, Iss 2 (2021)

Background Healthcare workers (HCWs) are believed to be at increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. It is not known to what extent the natural production of antibodies to SARS-CoV-2 is protective again

Externí odkaz: https://doaj.org/article/a9d89b47814a4ab8a8a7db494766c0cb

SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial.

Autor: Long, Merete B., Abo-Leyah, Hani, Yan Hui Giam, Vadiveloo, Thenmalar, Hull, Rebecca C., Keir, Holly R., Pembridge, Thomas, De Lima, Daniela Alferes, Delgado, Lilia, Inglis, Sarah K., Hughes, Chloe, Gilmour, Amy, Gierlinski, Marek, New, Benjamin J. M., MacLennan, Graeme, Dinkova-Kostova, Albena T., Chalmers, James D.

Publikováno v: ERJ Open Research; Mar2024, Vol. 10 Issue 2, p1-14, 14p

Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial

Autor: Holly R Keir, Merete B Long, Hani Abo-Leyah, Yan Hui Giam, Thenmalar Vadiveloo, Thomas Pembridge, Rebecca C Hull, Lilia Delgado, Margaret Band, Fiona McLaren-Neil, Simon Adamson, Eva Lahnsteiner, Amy Gilmour, Chloe Hughes, Benjamin JM New, David Connell, Rebecca Dowey, Helena Turton, Hollian Richardson, Diane Cassidy, Jamie Cooper, Jay Suntharalingam, Lavanya Diwakar, Peter Russell, Jonathan Underwood, Alexander Hicks, Davinder PS Dosanjh, Beth Sage, Devesh Dhasmana, Mark Spears, AA Roger Thompson, Christopher Brightling, Andrew Smith, Manish Patel, Jacob George, Alison M Condliffe, Amelia Shoemark, Graeme MacLennan, James D Chalmers, James Chalmers, Christine Almaden-Boyle, Jennifer Taylor, Jodie Strachan, Heather Loftus, Lesley Young, Angela Strachan, Kristina Pilvinyte, Petra Rauchhaus, Fiona Hogarth, Tricia Burns, Elizabeth Coote, Marney Keiller, Elizabeth Sage, David Miller, Davinder Dosanjh, Benjamin Sutton, Sharon Frayling, Matthew Haynes, Lauren Broad, Laura Jones, Karen Rahilly, Catherine Oliver, Terriann Evans, Andrea Balan, Rhys Davies, Donal Forde, Clemency Nye, Dr Haboubi, Zoe Hilton, Jennie Williams, Alison McQueen, Ian Edmond, Dario Salutous, Laura McGenily, Rhona Scott, Eilidh Henderson, Andrea Collins, Patrick Liu, Ana Morrow, Mandy Couser, Fleur Davey, Laura Wiffen, Lauren Fox, Mohamed Abdelrahim, Alexander Darbyshire, Elena Cowen, Megan Rowley, Benjamin Giles, Yingjia Yang, Tom Brown, Hitasha Rupani, Elizabeth Hawes, Debi Barnes, Fiona Brogan, Roneleeh Bungue-Tuble, Serena Howe, Charlotte Turner, Sonia Baryschpolec, Bev Longhurst, Maria Moon, Lynn Watkins, Michelle Baker-Moffat, Lisa Murray, Yasmin Harrington-Davies, Kate Burrows, Chrissie Minnis, Mary Wands, Adefunke Bamgboye, Charlotte Wong, Sarah Diver, Richard Russell, Hamish McAuley, Omer Elneima, Ahmed Yousuf, Paula McCourt, Beverley Hargadon, Sarah Parker, Michelle Bourne, Tom Hartley, Vidan Masan, Sharon Sturney, Rob MacKenzie, Clare Marchand, Rebecca Mason, Katie White, Alison Kirby, Manjula Meda, Joanne Finn, Sophie Harris, Carol Muir, Gemma Cook, Nikki Staines, Chris Cook, Alison Condliffe, Rebecca Hull, Paul Collini, Zoé Gabriel, Simon Hardman, Helen Newell, Janet Middle, Phillip Simpson, Hayley Colton, Joann Barker, Katie Birchall, Kate Harrington, Kay Housley, Rebecca Lenagh, Jayne Wilson, Joan Wesonga, Rachel Whitham, Sarah Bird, Yvonne Jackson, Angeline Mbuyisa, Samantha Anderson, Anna Wilson, Faith Kibutu, Sara Walker, Kay Cawthron, Irene Macharia, Lynne Smart, Anna Emery, Alice Howell, Elizabeth Hurditch, Amber Ford, Kim Turner, Lisa Watson, Helen Bowler, Tracy Jackson, Carol Jaques, Nichole Dyer, Shelley Ducker, Vicky Goodall, Emily Udale

This study was funded by an investigator-initiated research grant from Insmed (Bridgewater, NJ, USA). The authors acknowledge the funding and logistical support from the UK National Institute for Health and Care Research. Background: Neutrophil serin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f832a45ad7d7f0d50d9a326a100f7d7b
https://eprints.whiterose.ac.uk/190854/1/1-s2.0-S2213260022002612-main.pdf

Profiling systemic inflammation and neutrophil function in hospitalized patients with COVID19: results from PREDICT-COVID19

Autor: Merete Long, Holly R Keir, Yan Hui Giam, Andrew J M Howden, Alejandro J Brenes, Christina Rollings, Thomas Pembridge, Lilia Delgado, Hani Abo-Leyah, Rebecca C Hull, Amy Gilmour, Chloe Hughes, Rebecca Dowey, Helena Turton, Benjamin J M New, David W Connell, Hollian Richardson, Roger Thompson, Alison M Condliffe, Angus I Lamond, Diane M Cassidy, Amelia Shoemark, Doreen A Cantrell, James D Chalmers

Publikováno v: Respiratory infections and bronchiectasis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eff3008b446032b293a94a1411d7d5ea
https://doi.org/10.1183/23120541.lsc-2022.130

P93 Comparison of inflammatory profiles between COVID-19 and other acute lower respiratory tract infections: Results from the PREDICT-COVID19 study

Autor: Christopher R. Hughes, B. J. M. New, L. Delgado, T. Pembridge, James D. Chalmers, Diane Cassidy, M. B. Long, Amelia Shoemark, Holly R. Keir, Hollian Richardson, A. Gilmour, Yan Hui Giam, C. Hocking, D W Connell, R. Hull, H. A. Leyah

Publikováno v: COVID-19: clinical features and risk.

IntroductionCOVID-19 has been reported to induce a ‘cytokine storm’ distinct from other acute respiratory tract infections (LRTIs). Understanding the similarities and differences in inflammatory profiles between SARS-CoV-2 infection and other res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8b12ca3e9d34d6797b6ca223157f542
https://doi.org/10.1136/thorax-2021-btsabstracts.203