Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Yan Chen Shang"'
Publikováno v:
Molecules, Vol 14, Iss 9, Pp 3446-3485 (2009)
Nicotinamide, the amide form of vitamin B3 (niacin), is changed to its mononucleotide compound with the enzyme nicotinic acide/nicotinamide adenylyltransferase, and participates in the cellular energy metabolism that directly impacts normal physiolog
Externí odkaz:
https://doaj.org/article/897398e68427499abbaf5eb7410353a2
Publikováno v:
The Scientific World Journal, Vol 9, Pp 1072-1104 (2009)
Oxidative stress significantly impacts multiple cellular pathways that can lead to the initiation and progression of varied disorders throughout the body. It therefore becomes imperative to elucidate the components and function of novel therapeutic s
Externí odkaz:
https://doaj.org/article/fac38d753c4b489bb29659a4c96c8728
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45456 (2012)
Emerging strategies that center upon the mammalian target of rapamycin (mTOR) signaling for neurodegenerative disorders may bring effective treatment for a number of difficult disease entities. Here we show that erythropoietin (EPO), a novel agent fo
Externí odkaz:
https://doaj.org/article/e4748a24e1de4cf9a68d9afe7be07a80
Publikováno v:
Current Neurovascular Research. 10:29-38
More than 110 million individuals will suffer from cognitive loss worldwide by the year 2050 with a majority of individuals presenting with Alzheimer's disease (AD). Yet, successful treatments for etiologies that involve β.-amyloid (Aβ.) toxicity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360855b6d2d7c180f36983ac6bb21aa2
https://doi.org/10.2174/156720213804806007
https://doi.org/10.2174/156720213804806007
Publikováno v:
Trends in Molecular Medicine. 19:51-60
The mammalian target of rapamycin (mTOR), the key component of the protein complexes mTORC1 and mTORC2, plays a critical role in cellular development, tissue regeneration, and repair. mTOR signaling can govern not only stem cell development and quies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858af7b087e7d6f3350ca2dfa3785afe
https://doi.org/10.1016/j.molmed.2012.11.001
https://doi.org/10.1016/j.molmed.2012.11.001
Publikováno v:
Current Neurovascular Research. 10:54-69
As a member of the secreted extracellular matrix associated proteins of the CCN family, Wnt1 inducible signaling pathway protein 1 (WISP1/CCN4) is garnering increased attention not only as a potent proliferative entity, but also as a robust cytoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644fa1ccde23a828ac81db69bb97251f
https://doi.org/10.2174/1567202611310010008
https://doi.org/10.2174/1567202611310010008
Publikováno v:
Advanced Materials Research. 619:489-493
Hydraulic cylinder is an important actuator in hydraulic system, affecting the system running correctly and effectively. It’s closed and difficult to observe the failure symptoms, and result the difficulties of fault diagnosis and elimination for h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::765c0be35509fff78992b9ada8495c29
https://doi.org/10.4028/www.scientific.net/amr.619.489
https://doi.org/10.4028/www.scientific.net/amr.619.489
Publikováno v:
Progress in Neurobiology. 99:128-148
Neurodegenerative disorders affect a significant portion of the world's population leading to either disability or death for almost 30 million individuals worldwide. One novel therapeutic target that may offer promise for multiple disease entities th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626724c5c5ab07c2ae1bbbb720a1337b
https://doi.org/10.1016/j.pneurobio.2012.08.001
https://doi.org/10.1016/j.pneurobio.2012.08.001
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 9, Pp 11102-11129 (2012)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
New treatment strategies with erythropoietin (EPO) offer exciting opportunities to prevent the onset and progression of neurodegenerative disorders that currently lack effective therapy and can progress to devastating disability in patients. EPO and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3146c53f3eae73a182d2f0657f7766
http://www.mdpi.com/1422-0067/13/9/11102
http://www.mdpi.com/1422-0067/13/9/11102
Publikováno v:
Expert Opinion on Therapeutic Targets. 16:1203-1214
Apoptosis and autophagy impact cell death in multiple systems of the body. Development of new therapeutic strategies that target these processes must address their complex role during developmental cell growth as well as during the modulation of toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c34b9f5badd0b7d2aec391486be185
https://doi.org/10.1517/14728222.2012.719499
https://doi.org/10.1517/14728222.2012.719499