Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Yan Burelle"'
Autor:
Charlotte Burelle, Valentin Clapatiuc, Sonia Deschênes, Alexanne Cuillerier, Marine De Loof, Marie-Ève Higgins, Hugues Boël, Caroline Daneault, Billie Chouinard, Marie-Élaine Clavet, Nolwenn Tessier, Isabelle Croteau, Geneviève Chabot, Catherine Martel, Martin G. Sirois, Sylvie Lesage, Yan Burelle, Matthieu Ruiz
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Lean patients with NAFLD may develop cardiac complications independently of pre-existent metabolic disruptions and comorbidities. To address the underlying mechanisms independent of the development of obesity, we used a murine model of hepat
Externí odkaz:
https://doaj.org/article/88f52e0afd2145fc82e7f585470ab99c
Autor:
Nicolas Collao, Donna D'Souza, Laura Messeiller, Evan Pilon, Jessica Lloyd, Jillian Larkin, Matthew Ngu, Alexanne Cuillerier, Alexander E. Green, Keir J. Menzies, Yan Burelle, Michael De Lisio
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 2335-2349 (2023)
Abstract Background Radiation‐induced muscle pathology, characterized by muscle atrophy and fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic radiation exposure particularly in juvenile cancer survivors. In he
Externí odkaz:
https://doaj.org/article/7b76464a461644d6baba5850004e0251
Autor:
Justine Dontaine, Asma Bouali, Frederic Daussin, Laurent Bultot, Didier Vertommen, Manon Martin, Raahulan Rathagirishnan, Alexanne Cuillerier, Sandrine Horman, Christophe Beauloye, Laurent Gatto, Benjamin Lauzier, Luc Bertrand, Yan Burelle
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
An in vitro assay in isolated heart mitochondria reveals that O-GlcNAcase inhibitor NButGT rapidly increases protein O-GlcNAcylation leading to increased respiratory capacity and complex I activity and decreased ROS release.
Externí odkaz:
https://doaj.org/article/82461742574a45b882dff02102e4af48
Autor:
Alexanne Cuillerier, Matthieu Ruiz, Caroline Daneault, Anik Forest, Jenna Rossi, Goutham Vasam, George Cairns, Virgilio Cadete, The LSFC Consortium, Christine Des Rosiers, Yan Burelle
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Cuillerier et al. investigate compensatory mechanisms underlying survival of mice with a liver-specific knockout of the mitochondrial mRNA-binding protein Lrpprc. They propose various mechanisms operating along the OXPHOS assembly line, including mit
Externí odkaz:
https://doaj.org/article/12fd84a866144bb181cee682a2036138
Autor:
Ava Liaghati, Chantal A. Pileggi, Gaganvir Parmar, David A. Patten, Nina Hadzimustafic, Alexanne Cuillerier, Keir J. Menzies, Yan Burelle, Mary-Ellen Harper
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Glutathione is an important antioxidant that regulates cellular redox status and is disordered in many disease states. Glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase that plays a pivotal role in redox control by catalyzing reversible
Externí odkaz:
https://doaj.org/article/b9ee757afd6042619bdf440302b6f161
Autor:
David N. Huynh, Hanan Elimam, Valérie L. Bessi, Liliane Ménard, Yan Burelle, Riccarda Granata, André C. Carpentier, Huy Ong, Sylvie Marleau
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Unacylated ghrelin (UAG), the most abundant form of ghrelin in circulation, has been shown to exert cardioprotective effect in experimental cardiopathies. The present study aimed to investigate the cardioprotective effect of a linear bioactive fragme
Externí odkaz:
https://doaj.org/article/1d1f6ecd9b784e4d9f723ea621474e82
Publikováno v:
Biology, Vol 9, Iss 12, p 481 (2020)
The fundamental importance of functional mitochondria in the survival of most eukaryotic cells, through regulation of bioenergetics, cell death, calcium dynamics and reactive oxygen species (ROS) generation, is undisputed. However, with new avenues o
Externí odkaz:
https://doaj.org/article/fb11f685f0ab468dae14d25df778a47b
Autor:
Julie Thompson Legault, Laura Strittmatter, Jessica Tardif, Rohit Sharma, Vanessa Tremblay-Vaillancourt, Chantale Aubut, Gabrielle Boucher, Clary B. Clish, Denis Cyr, Caroline Daneault, Paula J. Waters, Azadeh Aliskashani, Bruce G. Allen, Claudine Beauchamp, Chantal Bemeur, Yan Burelle, Guy Charron, Lise Coderre, Christine Des Rosiers, Sonia Deschênes, François Labarthe, Jeannine Landry, Catherine Laprise, Geneviève Lavallée, Pierre Lavoie, Bruno Maranda, Charles Morin, Yvette Mukaneza, Tamiko Nishimura, John D. Rioux, Marie-Ève Rivard, Florin Sasarman, Eric A. Shoubridge, Nancy Tremblay, Luc Vachon, Josée Villeneuve
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 981-989 (2015)
A decline in mitochondrial respiration represents the root cause of a large number of inborn errors of metabolism. It is also associated with common age-associated diseases and the aging process. To gain insight into the systemic, biochemical consequ
Externí odkaz:
https://doaj.org/article/9a62c7ac67234db5a1b82fa740ce6d1e
Autor:
Yan Burelle, Chantal Bemeur, Marie-Eve Rivard, Julie Thompson Legault, Gabrielle Boucher, LSFC Consortium, Charles Morin, Lise Coderre, Christine Des Rosiers
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120767 (2015)
Mutations in LRPPRC are responsible for the French Canadian variant of Leigh Syndrome (LSFC), a severe disorder characterized biochemically by a tissue-specific deficiency of cytochrome c oxidase (COX) and clinically by the occurrence of severe and d
Externí odkaz:
https://doaj.org/article/3e89d080465f4c9fa1d1564a43229449
Autor:
Jennifer Marton, Danica Albert, Sean A Wiltshire, Robin Park, Arthur Bergen, Salman Qureshi, Danielle Malo, Yan Burelle, Silvia M Vidal
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138222 (2015)
Coxsackievirus type B3 (CVB3) is a cardiotropic enterovirus. Infection causes cardiomyocyte necrosis and myocardial inflammation. The damaged tissue that results is replaced with fibrotic or calcified tissue, which can lead to permanently altered car
Externí odkaz:
https://doaj.org/article/794c48f3d4514857872105c4898b5305