Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yan Baglo"'
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Photoimmunotherapy involves targeted delivery of photosensitizers via an antibody conjugate (i.e., photoimmunoconjugate, PIC) followed by light activation for selective tumor killing. The trade-off between PIC selectivity and PIC
Externí odkaz:
https://doaj.org/article/8814d006a2b24741a8b63cac010f7956
Autor:
Yan Baglo, Aaron J. Sorrin, Xiaocong Pu, Cindy Liu, Jocelyn Reader, Dana M. Roque, Huang-Chiao Huang
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101198- (2021)
P-glycoprotein (P-gp) is an adenosine triphosphate (ATP)-dependent drug efflux protein commonly associated with multidrug resistance in cancer chemotherapy. In this report, we used a dual-fluorescent co-culture model to study the population dynamics
Externí odkaz:
https://doaj.org/article/b3f0b984c71d4adc9972dd0a19832dff
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65200 (2013)
Photodynamic therapy (PDT) is a safe and effective method currently used in the treatment of skin cancer. In ALA-based PDT, 5-aminolevulinic acid (ALA), or ALA esters, are used as pro-drugs to induce the formation of the potent photosensitizer protop
Externí odkaz:
https://doaj.org/article/700228219c63446d9dfd48cc3d19c013
Autor:
Tayyaba Hasan, Michael Pigula, Sriram Anbil, Imran Rizvi, Yan Baglo, Joyce Liu, Huang-Chiao Huang
Representative size distribution of nanoliposomal irinotecan (nal-IRI) and absorbance spectrum of nal-IRI in DMSO. (A) Mono-dispersed nal-IRI is approximately 115 nm in diameter with a Polydispersity index below 0.1. (B) Nal-IRI absorbance spectrum w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a8785b076d8a2e3cb1b16d57b00aa9
https://doi.org/10.1158/1535-7163.22509412.v1
https://doi.org/10.1158/1535-7163.22509412.v1
Autor:
Tayyaba Hasan, Michael Pigula, Sriram Anbil, Imran Rizvi, Yan Baglo, Joyce Liu, Huang-Chiao Huang
Preliminary analysis of costs related to the side effect management for irinotecan-based combination therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9801450ed476bef4ec6b70f52cc59d
https://doi.org/10.1158/1535-7163.22509397.v1
https://doi.org/10.1158/1535-7163.22509397.v1
Autor:
Tayyaba Hasan, Imran Rizvi, Edward V. Maytin, Mari Mino-Kenudson, Diane M. Simeone, Pushpamali De Silva, Yan Baglo, Mans Broekgaarden, Srivalleesha Mallidi, Huang-Chiao Huang, Michael Pigula, Sriram Anbil
Supplementary Methods Supplemental Figure 1: The MIA-PaCa-2 + PCAF model exhibits histologic features consistent with desmoplasia 90 days post implantation Supplemental Figure 2: 1 μM calcipitriol activates the vitamin D receptor (VDR) in cancer ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001caed6246fa8dbf16ec250549cd00e
https://doi.org/10.1158/1535-7163.22520601.v1
https://doi.org/10.1158/1535-7163.22520601.v1
Autor:
Tayyaba Hasan, Imran Rizvi, Edward V. Maytin, Mari Mino-Kenudson, Diane M. Simeone, Pushpamali De Silva, Yan Baglo, Mans Broekgaarden, Srivalleesha Mallidi, Huang-Chiao Huang, Michael Pigula, Sriram Anbil
Patients with cancer often confront the decision of whether to continue high-dose chemotherapy at the expense of cumulative toxicities. Reducing the dose of chemotherapy regimens while preserving efficacy is sorely needed to preserve the performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e774c1d9962c91ce98c83f84e42ae64
https://doi.org/10.1158/1535-7163.c.6542694
https://doi.org/10.1158/1535-7163.c.6542694
Autor:
Tayyaba Hasan, Michael Pigula, Sriram Anbil, Imran Rizvi, Yan Baglo, Joyce Liu, Huang-Chiao Huang
Mechanism-inspired drug repurposing that augments standard treatments offers a cost-effective and rapid route toward addressing the burgeoning problem of plateauing of effective therapeutics for drug-resistant micrometastases. We show that the antibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b98bbe0da77f21828623d25d63dcc583
https://doi.org/10.1158/1535-7163.c.6539284.v1
https://doi.org/10.1158/1535-7163.c.6539284.v1
Autor:
Tayyaba Hasan, Jonathan Fitzgerald, Brian W. Pogue, Steve Pereira, Douglas Hayden, Nancy Paz, Yan Baglo, Helen Lee, Ashish Kalra, Sriram Anbil, Joyce Liu, Imran Rizvi, Huang-Chiao Huang
Physiologic barriers to drug delivery and selection for drug resistance limit survival outcomes in cancer patients. In this study, we present preclinical evidence that a subtumoricidal photodynamic priming (PDP) strategy can relieve drug delivery bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1186c0ce24e7738d599d2426f9bfc09b
https://doi.org/10.1158/0008-5472.c.6509981.v1
https://doi.org/10.1158/0008-5472.c.6509981.v1
Autor:
Tayyaba Hasan, Jonathan Fitzgerald, Brian W. Pogue, Steve Pereira, Douglas Hayden, Nancy Paz, Yan Baglo, Helen Lee, Ashish Kalra, Sriram Anbil, Joyce Liu, Imran Rizvi, Huang-Chiao Huang
Sub-tumouricidal PDP does not increase systemic toxicity of chemotherapy. Changes in mouse body weight were monitored longitudinally before and after treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d17385478ee74fce70ce9d126fa41c
https://doi.org/10.1158/0008-5472.22417946
https://doi.org/10.1158/0008-5472.22417946