Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Yan, Jouroukhin"'
Autor:
Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange P. Brown, Mikhail V. Pletnikov, Atsushi Kamiya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in neurons and astrocytes, but also in microglia, which shape synaptic connections durin
Externí odkaz:
https://doaj.org/article/26cf4f08ed724225b7ffc7f3a89a4583
Autor:
Kateryna Murlanova, Yan Jouroukhin, Ksenia Novototskaya-Vlasova, Shovgi Huseynov, Olga Pletnikova, Michael J. Morales, Yun Guan, Atsushi Kamiya, Dwight E. Bergles, David M. Dietz, Mikhail V. Pletnikov
Publikováno v:
Cells, Vol 12, Iss 10, p 1412 (2023)
Astrocytes express mu/µ opioid receptors, but the function of these receptors remains poorly understood. We evaluated the effects of astrocyte-restricted knockout of µ opioid receptors on reward- and aversion-associated behaviors in mice chronicall
Externí odkaz:
https://doaj.org/article/26d7ea31e0aa4d55a6b9ddc5ba3e91bc
Autor:
Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108610- (2021)
Summary: Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axon
Externí odkaz:
https://doaj.org/article/3365b3bdc34a429095f1971a8c5318cd
Publikováno v:
Neurobiology of Disease, Vol 56, Iss , Pp 79-94 (2013)
NAP (davunetide) is a novel neuroprotective compound with mechanism of action that appears to involve microtubule (MT) stabilization and repair. To evaluate, for the first time, the impact of NAP on axonal transport in vivo and to translate it to neu
Externí odkaz:
https://doaj.org/article/a98b3551b057453c9ebf7649b11797b1
Autor:
Kateryna Murlanova, Yan Jouroukhin, Shovgi Huseynov, Olga Pletnikova, Michael J. Morales, Yun Guan, Jay M. Baraban, Dwight E. Bergles, Mikhail V. Pletnikov
Publikováno v:
Glia
Mitochondria are abundant in the fine processes of astrocytes, however, potential roles for astrocyte mitochondria remain poorly understood. In the present study, we performed a systematic examination of the effects of abnormal oxidative phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f45851da58eabd181f24aeb503a7b81
https://pubmed.ncbi.nlm.nih.gov/35275429
https://pubmed.ncbi.nlm.nih.gov/35275429
Autor:
Juhyun Kim, Dong Won Kim, Adrian Lee, Madisen Mason, Yan Jouroukhin, Hyewon Woo, Robert H. Yolken, Mikhail V. Pletnikov
Publikováno v:
Kim, J, Kim, D W, Lee, A, Mason, M, Jouroukhin, Y, Woo, H, Yolken, R H & Pletnikov, M V 2022, ' Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice ', Journal of Neuroscience Research, vol. 100, no. 2, pp. 444-460 .
Aarhus University
Kim, J, Kim, D W, Lee, A, Mason, M, Jouroukhin, Y, Woo, H, Yolken, R H & Pletnikov, M V 2022, ' Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice ', Journal of Neuroscience Research, bind 100, nr. 2, s. 444-460 .
Aarhus University
Kim, J, Kim, D W, Lee, A, Mason, M, Jouroukhin, Y, Woo, H, Yolken, R H & Pletnikov, M V 2022, ' Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice ', Journal of Neuroscience Research, bind 100, nr. 2, s. 444-460 .
Emerging evidence indicates that probiotics can influence the gut-brain axis to ameliorate somatic and behavioral symptoms associated with brain disorders. However, whether probiotics have effects on the electrophysiological activities of individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6cac98ebd6df69d22c6b276911c237
https://pure.au.dk/portal/da/publications/homeostatic-regulation-of-neuronal-excitability-by-probiotics-in-male-germfree-mice(7736130a-c8bc-442f-80f5-c95a798829c2).html
https://pure.au.dk/portal/da/publications/homeostatic-regulation-of-neuronal-excitability-by-probiotics-in-male-germfree-mice(7736130a-c8bc-442f-80f5-c95a798829c2).html
NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
Autor:
Natalia Shiryaev, Yan Jouroukhin, Eliezer Giladi, Eleni Polyzoidou, Nikolaos C. Grigoriadis, Hanna Rosenmann, Illana Gozes
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 2, Pp 381-388 (2009)
NAP (NAPVSIPQ) provides broad neuroprotection through microtubule interaction. Here, NAP was investigated for neuroprotection in an in vivo tauopathy model. Transgenic mice (2-month-old) that express the human double mutant tau protein [P301S;K257T]
Externí odkaz:
https://doaj.org/article/0b1f238518e24021aab76d3b7b005543
Autor:
Yan Jouroukhin, Atsushi Saito, Bagrat Abazyan, A. V. Shevelkin, Atsushi Kamiya, Jonathan Pevsner, Mikhail V. Pletnikov, Yuto Hasegawa, Xiaolei Zhu
Publikováno v:
Biological Psychiatry. 85:891-903
Background Although several studies have linked adolescent cannabis use to long-term cognitive dysfunction, there are negative reports as well. The fact that not all users develop cognitive impairment suggests a genetic vulnerability to adverse effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5484aa9a6a801501939f7344e526f2ae
https://doi.org/10.1016/j.biopsych.2018.07.024
https://doi.org/10.1016/j.biopsych.2018.07.024
Autor:
Brett M. Morrison, Thomas Philips, Svetlana Vidensky, Mohamed H. Farah, Dwight E. Bergles, Yevgeniya A. Mironova, Jeffrey D. Rothstein, Yan Jouroukhin, Jeannie Chew, Mikhail V. Pletnikov
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108610-(2021)
Cell reports
Cell reports
SUMMARY Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467cf2ab1a7efcc04498c7efda34e298
http://www.sciencedirect.com/science/article/pii/S2211124720315990
http://www.sciencedirect.com/science/article/pii/S2211124720315990
Autor:
Akira Sawa, Yan Jouroukhin, Chantelle E. Terrillion, Yuto Hasegawa, Olga Mychko, Atsushi Kamiya, A. V. Shevelkin, Mikhail V. Pletnikov
Publikováno v:
Hum Mol Genet
Our understanding of the contribution of genetic risk factors to neuropsychiatric diseases is limited to abnormal neurodevelopment and neuronal dysfunction. Much less is known about the mechanisms whereby risk variants could affect the physiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1c8313d79555e9fe2afc19ef45cee9
https://pubmed.ncbi.nlm.nih.gov/32803234
https://pubmed.ncbi.nlm.nih.gov/32803234