Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yamuna Kalyani Mathiharan"'
Autor:
Yamuna Kalyani Mathiharan, Ian W. Glaaser, Yulin Zhao, Michael J. Robertson, Georgios Skiniotis, Paul A. Slesinger
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109619- (2021)
Summary: G-protein-gated inwardly rectifying potassium (GIRK) channels are important for determining neuronal excitability. In addition to G proteins, GIRK channels are potentiated by membrane cholesterol, which is elevated in the brains of people wi
Externí odkaz:
https://doaj.org/article/959412e4de4b446ba8d44e4d35df82c8
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55978 (2013)
Domain swapping is an interesting feature of some oligomeric proteins in which each protomer of the oligomer provides an identical surface for exclusive interaction with a segment or domain belonging to another protomer. Here we report results of mut
Externí odkaz:
https://doaj.org/article/b85a98117aa048719148b17f1d909185
Autor:
Michael J. Capper, Shifan Yang, Alexander C. Stone, Sezen Vatansever, Gregory Zilberg, Yamuna Kalyani Mathiharan, Raul Habib, Keino Hutchinson, Avner Schlessinger, Mihaly Mezei, Roman Osman, Bin Zhang, Daniel Wacker
Anion Exchanger 1 (AE1, SLC4A1) is the primary bicarbonate (HCO3-) transporter expressed in erythrocyte membranes where it mediates transport of CO2between lungs and other tissues via import/export of bicarbonate. It is also a key regulator of erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2099c39f01b9568db6c01259a84f2c89
https://doi.org/10.1101/2022.02.11.480130
https://doi.org/10.1101/2022.02.11.480130
Autor:
Ian W. Glaaser, Yamuna Kalyani Mathiharan, Georgios Skiniotis, Michael J. Robertson, Yulin Zhao, Paul A. Slesinger
Publikováno v:
SSRN Electronic Journal.
G protein-gated inwardly rectifying potassium (GIRK) channels are important for determining neuronal excitability and have been implicated in a number of neurological diseases. In addition to G proteins, GIRK channels are also regulated by membrane c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d43ea44d2de3a15ea3da12c65a4eaa
https://doi.org/10.2139/ssrn.3779553
https://doi.org/10.2139/ssrn.3779553
Autor:
Georgios Skiniotis, Yamuna Kalyani Mathiharan, Patrick J. Lupardus, Leon Su, Christoph Thomas, Jamie B. Spangler, Kevin Jude, Lauren Kate Ely, Caleb R. Glassman, K. Christopher Garcia, Ouliana Panova
Publikováno v:
Cell
Summary Interleukin-12 (IL-12) and IL-23 are heterodimeric cytokines that are produced by antigen-presenting cells to regulate the activation and differentiation of lymphocytes, and they share IL-12Rβ1 as a receptor signaling subunit. We present a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd4737db9e4ddaaee7ed9f215ed2797
https://pubmed.ncbi.nlm.nih.gov/33606986
https://pubmed.ncbi.nlm.nih.gov/33606986
Autor:
Joseph D. Puglisi, Aaron T. Coey, Yamuna Kalyani Mathiharan, Lauren Madigan, Elisabetta Viani Puglisi, Dong-Hua Chen, Daniel J. Barrero, Georgios Skiniotis, Kevin P. Larsen, Kalli Kappel
Publikováno v:
Nature
Reverse transcription of the HIV-1 RNA genome into double-stranded DNA is a central step in viral infection1 and a common target of antiretroviral drugs2. The reaction is catalysed by viral reverse transcriptase (RT)3,4 that is packaged in an infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ed7d7ab9d40e25289268de8b869d48
https://doi.org/10.1038/s41586-018-0055-9
https://doi.org/10.1038/s41586-018-0055-9
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:2303-2311
Stationary phase survival protein SurE from Salmonella typhimurium is a dimeric protein formed by the swapping of a tetramerization loop involved in the formation of a loose tetramer and a C-terminal helix. It functions as a phosphatase. The two-fold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df85359f2587114c7fb56dc46a531d26
https://doi.org/10.1080/07391102.2017.1351400
https://doi.org/10.1080/07391102.2017.1351400
Publikováno v:
Acta Crystallographica Section D Structural Biology. 73:609-617
The determination of the crystal structure of a mutant protein using phases based on a previously determined crystal structure of the wild-type protein is often a straightforward molecular-replacement protocol. Such a structure determination may be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a759f0c270959b9014f487d29bdfed63
https://doi.org/10.1107/s2059798317007677
https://doi.org/10.1107/s2059798317007677
Publikováno v:
Biophysical Journal. 118:497a-498a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76547838dd40ae57c442e08cb105d6f4
https://doi.org/10.1016/j.bpj.2019.11.2749
https://doi.org/10.1016/j.bpj.2019.11.2749
Autor:
Georgios Skiniotis, Dong-Hua Chen, Kevin P. Larsen, Joseph D. Puglisi, Kalli Kappel, Elisabetta Viani Puglisi, Yamuna Kalyani Mathiharan, Lauren Madigan, Aaron T. Coey
Publikováno v:
Biophysical Journal. 114:193a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b886bbf872efa7fce9cc2c0ff737ce1
https://doi.org/10.1016/j.bpj.2017.11.1080
https://doi.org/10.1016/j.bpj.2017.11.1080