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Efficacy and Safety of 'Fixed Dose' versus 'Loose' Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial.

Autor: Aseffa A; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia., Chukwu JN; German Leprosy and Tuberculosis Relief Association, Hill View, Enugu, Nigeria., Vahedi M; Special Programme for Research and Training in Tropical Diseases (WHO/TDR), Avenue Appia, Geneva, Switzerland., Aguwa EN; University of Nigeria Enugu Campus, Enugu, Nigeria., Bedru A; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia., Mebrahtu T; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia., Ezechi OC; Division of Clinical Sciences, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria., Yimer G; Department of Pharmacology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia., Yamuah LK; Armauer Hansen Research Institute (AHRI), ALERT Compound, Addis Ababa, Ethiopia., Medhin G; Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia., Connolly C; Biostatistics Unit, Medical Research Council, Durban, South Africa., Rida W; Biostatistics Consultant, Arlington, Virginia, United States of America., Aderaye G; Department of Internal Medicine, Addis Ababa University, Addis Ababa, Ethiopia., Zumla AI; Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, United Kingdom., Onyebujoh PC; World Health Organization, Inter-country Support Team for East and Southern Africa, Harare, Zimbabwe.

Publikováno v: PloS one [PLoS One] 2016 Jun 20; Vol. 11 (6), pp. e0157434. Date of Electronic Publication: 2016 Jun 20 (Print Publication: 2016).

Comparison of Efficacy and Safety of Ciclosporin to Prednisolone in the Treatment of Erythema Nodosum Leprosum: Two Randomised, Double Blind, Controlled Pilot Studies in Ethiopia.

Autor: Lambert SM; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Nigusse SD; All Africa Leprosy Rehabilitation and Training (ALERT) Center, Addis Ababa, Ethiopia., Alembo DT; All Africa Leprosy Rehabilitation and Training (ALERT) Center, Addis Ababa, Ethiopia., Walker SL; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Nicholls PG; School of Health Sciences, University of Southampton, Southampton, United Kingdom., Idriss MH; All Africa Leprosy Rehabilitation and Training (ALERT) Center, Addis Ababa, Ethiopia., Yamuah LK; Data Management, Armauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia., Lockwood DN; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2016 Feb 26; Vol. 10 (2), pp. e0004149. Date of Electronic Publication: 2016 Feb 26 (Print Publication: 2016).