Accuracy of the Fracture Risk Assessment Tool for judging pharmacotherapy initiation for primary osteoporosis.

Autor: Fujimaki H; Department of Orthopaedic Surgery, Yokohama Ekisaikai Hospital, 1-2 Yamada-cho, Naka-ku, Yokohama City, 231-0036, Japan. try_try_try_try_again@yahoo.co.jp.; Department of Orthopaedic Surgery, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama City, 236-0004, Japan. try_try_try_try_again@yahoo.co.jp., Tomioka M; Department of Orthopaedic Surgery, Yokohama Ekisaikai Hospital, 1-2 Yamada-cho, Naka-ku, Yokohama City, 231-0036, Japan., Kanoshima Y; Department of Orthopaedic Surgery, Yokohama Ekisaikai Hospital, 1-2 Yamada-cho, Naka-ku, Yokohama City, 231-0036, Japan., Morita A; Department of Orthopaedic Surgery, Yokohama Ekisaikai Hospital, 1-2 Yamada-cho, Naka-ku, Yokohama City, 231-0036, Japan.; Department of Orthopaedic Surgery, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama City, 236-0004, Japan., Yamori T; Department of Orthopaedic Surgery, Yokohama Ekisaikai Hospital, 1-2 Yamada-cho, Naka-ku, Yokohama City, 231-0036, Japan., Inaba Y; Department of Orthopaedic Surgery, Yokohama City University, 3-9, Fukuura, Kanazawa-ku, Yokohama City, 236-0004, Japan.

Publikováno v: Journal of bone and mineral metabolism [J Bone Miner Metab] 2022 Sep; Vol. 40 (5), pp. 860-868. Date of Electronic Publication: 2022 Aug 10.

Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor.

Autor: Nishiya N; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Oku Y; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Ishikawa C; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Fukuda T; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, Nagasaki, Japan., Dan S; Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Mashima T; Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Ushijima M; Clinical Research and Medical Development Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Furukawa Y; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Sasaki Y; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Otsu K; Division of Developmental Biology and Regenerative Medicine, Department of Anatomy, Iwate Medical University, Yahaba, Japan., Sakyo T; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Abe M; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Yonezawa H; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan., Ishibashi F; Division of Marine Life Science and Biochemistry, Graduate School of Fisheries and Environmental Sciences, Nagasaki University, Nagasaki, Japan., Matsuura M; Teikyo University Graduate School of Public Health, Tokyo, Japan., Tomida A; Division of Genome Research, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Seimiya H; Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Yamori T; Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan., Iwao M; Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, Nagasaki, Japan., Uehara Y; Division of Integrated Information for Pharmaceutical Sciences, Department of Clinical Pharmacy, Iwate Medical University School of Pharmacy, Yahaba, Japan.

Publikováno v: Cancer science [Cancer Sci] 2021 May; Vol. 112 (5), pp. 1963-1974. Date of Electronic Publication: 2021 Mar 24.

miR-122/NEGR1 axis contributes colorectal cancer liver metastasis by PI3K/AKT pathway and macrophage modulation.

Autor: Dai, Shipeng^1,2 (AUTHOR), Zhuang, Haiwen³ (AUTHOR), Li, Zhuozheng⁴ (AUTHOR), Chen, Zhongda¹ (AUTHOR), Chai, Yue² (AUTHOR), Zhou, Qing¹ (AUTHOR) zhouqingzy@163.com

Publikováno v: Journal of Translational Medicine. 11/25/2024, Vol. 22 Issue 1, p1-16. 16p.

The Importance of Phosphoinositide 3-Kinase in Neuroinflammation.

Autor: Wright, Brock^1,2,3 (AUTHOR) brock.wright@deakin.edu.au, King, Samuel^1,2,3 (AUTHOR) samuel.king@deakin.edu.au, Suphioglu, Cenk^1,2,3 (AUTHOR) cenk.suphioglu@deakin.edu.au

Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11638. 27p.

ZSTK474 targeting PIK3R3 inhibits the Wilms' tumor through G0 / G1 phase arrest.

Autor: Li, Maoxian^1,2 (AUTHOR), Liu, Jiayan¹ (AUTHOR), Jin, Liming¹ (AUTHOR), Mi, Tao¹ (AUTHOR), Zhang, Zhaoxia¹ (AUTHOR), Zhanghuang, Chenghao¹ (AUTHOR), Li, Mujie¹ (AUTHOR), Wang, Jinkui¹ (AUTHOR), Wu, Xin¹ (AUTHOR), Wang, Zhaoying¹ (AUTHOR), Wang, Zhang¹ (AUTHOR), He, Dawei¹ (AUTHOR) hedawei@hospital.cqmu.edu.cn

Publikováno v: PLoS ONE. 10/28/2024, Vol. 19 Issue 10, p1-22. 22p.