Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yamit Hagalili"'
Publikováno v:
Journal of Biological Chemistry. 285:6996-7005
The role of the L-type calcium channel (Cav1.2) as a molecular switch that triggers secretion prior to Ca(2+) transport has previously been demonstrated in bovine chromaffin cells and rat pancreatic beta cells. Here, we examined the effect of specifi
Publikováno v:
Biochemistry. 47:13822-13830
Neurotransmitter release involves two consecutive Ca(2+)-dependent steps, an initial Ca(2+) binding to the selectivity filter of voltage-gated Ca(2+) channels (VGCC) followed by Ca(2+) binding to synaptic vesicle protein. The unique Ca(2+)-binding si
Publikováno v:
Journal of Neurochemistry. 96:585-597
Large numbers of neurons are eliminated by apoptosis during nervous system development. For instance, in the mouse dorsal root ganglion (DRG), the highest incidence of cell death occurs between embryonic days 12 and 14 (E12-E14). While the cause of c
Publikováno v:
Proceedings of the National Academy of Sciences. 101:2578-2583
Neurotransmitter release is a multistep process that is coordinated by a large number of synaptic proteins and depends on proper protein–protein interactions. Using morphological, capacitance, and amperometric measurements, we investigated the effe
Publikováno v:
Biochemistry. 51(48)
The activation of the ryanodine Ca(2+) release channels (RyR2) by the entry of Ca(2+) through the L-type Ca(2+) channels (Cav1.2) is believed to be the primary mechanism of excitation-contraction (EC) coupling in cardiac cells. This proposed mechanis