Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yamila Verdecia Reyes"'
Autor:
Bárbara B. Garrido-Suárez, Gabino Garrido, Addis Bellma Menéndez, Guillermo Aparicio, Odalys Valdés, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 9, Iss 2, Pp 165-174 (2021)
Context: JM-20 is a hybrid synthetic molecule, which is based on a multimodal drug design paradigm for cerebrovascular disease. In addition to its neuroprotective effects, JM-20 also decreased sciatic nerve chronic constriction injury (CCI)-induced m
Externí odkaz:
https://doaj.org/article/a76b9560de134db485ff67a89e882b23
Autor:
Yanier Núñez Figueredo, Jeney Ramírez-Sanchez, Gisele Hansel, Gilberto L. Pardo-Andreu, Nelson Merino, Guillermo Aparicio, Rene Delgado-Hernández, Laura García-Pupo, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Diogo O. Souza
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 4, Iss 4, Pp 153-158 (2016)
Context: Despite the great mortality and morbidity of stroke, treatment options remain limited. We previously showed that JM-20, a novel synthetic molecule, possessed a strong neuroprotective effect in rats subjected to transient middle cerebral arte
Externí odkaz:
https://doaj.org/article/af943445e2ab4e7283e9521f74014c51
Autor:
Fillipe M. de Araújo, Luis Arturo Fonseca-Fonseca, Victor Diogenes Amaral da Silva, Maylin Wong-Guerra, Yamila Verdecia-Reyes, Tiago F. Outeiro, Jeney Ramírez-Sánchez, Estael Ochoa-Rodríguez, Silvia Lima Costa, Yanier Nuñez-Figueredo, Rejane Conceição Santana, Padrón Yaquis Alejandro Saúl
Publikováno v:
NeuroToxicology. 82:89-98
We have previously shown that JM-20, a new chemical entity consisting of 1,5-benzodiazepine fused to a dihydropyridine moiety, protects against rotenone-induced neurotoxicity in an experimental model of Parkinson's disease (PD). The aim of this study
Autor:
Luis Arturo Fonseca-Fonseca, René Delgado-Hernández, Estael Ochoa-Rodríguez, Elisa Nicoloso Simões-Pires, Jeney Ramírez-Sánchez, Yamila Verdecia-Reyes, Yanier Nuñez-Figueredo, Maylin Wong-Guerra, Gilberto L. Pardo-Andreu, Laura García-Pupo, Christianne Gazzana Salbego, Diogo O. Souza
Publikováno v:
European journal of pharmacology. 899
Cerebral ischemia constitutes the most frequent type of cerebrovascular disease. The reduction of blood supply to the brain initiates the ischemic cascade starting from ionic imbalance to subsequent glutamate excitotoxicity, neuroinflammation and oxi
Autor:
Sérgio H. Ferreira, Yamila Verdecia-Reyes, Gabino Garrido, Odalys Valdés, Nelson Merino, Marian Castro-Labrada, Estael Ochoa-Rodríguez, René Delgado-Hernández, Zenia Pardo, Bárbara B. Garrido-Suárez, Jozi Godoy-Figueiredo
Publikováno v:
Brain research bulletin. 165
The present study examines the possible effect of the novel hybrid molecule JM-20 (3-ethoxycarbonyl-2-methyl-4-(2-nitrophenyl)-411-dihydro-1H-pyrido[2,3-b] [1,5] benzodiazepine) on pain-related behaviours in a persistent pain model (5% formalin test)
Autor:
René Delgado-Hernández, Christianne Gazzana Salbego, Diogo O. Souza, Yanier Nuñez-Figueredo, Elisa Nicoloso Simões Pires, Gilberto L. Pardo-Andreu, Yamila Verdecia-Reyes, Estael Ochoa-Rodríguez, Gisele Hansel, André Meneghetti, Jeney Ramírez-Sánchez
Publikováno v:
Molecular Neurobiology. 56:502-512
Stroke is frequently associated with severe neurological decline and mortality, and its incidence is expected to increase due to aging population. The only available pharmacological treatment for cerebral ischemia is thrombolysis, with narrow therape
Autor:
Wong Guerra Maylin, René Delgado Hernádez, Estael Ochoa-Rodríguez, Juan Segura-Aguilar, Luis Arturo Fonseca-Fonseca, Wagno Alcântara de Santana, Yamila Verdecia-Reyes, Silva Lima Costa, N.J. Menezes-Filho, Yanier Nuñez-Figueredo, Joana Oliveira, Jeney Ramírez Sánchez, Victor Diogenes Amaral da Silva, Teresa Cristina Silva Costa
Publikováno v:
Neurotoxicity Research. 36:279-291
The etiology of Parkinson’s disease is not completely understood and is believed to be multifactorial. Neuronal disorders associated to oxidative stress and mitochondrial dysfunction are widely considered major consequences. The aim of this study w
Autor:
Andréia Machado Leopoldino, Estael Ochoa-Rodríguez, Lucas Oliveira Sousa, Norberto Peporine Lopes, Carlos Curti, Gilberto L. Pardo-Andreu, Javier Marín-Prida, Lays M. Sobral, Renata Nishida Goto, Cristiana Bernadelli Garcia, Yamila Verdecia-Reyes
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
This study aims to examine the effects of a new 1,4-dihydropyridine derivative, VdiE-2N, on cell signaling pathways and mitochondrial events in head and neck squamous cell carcinoma (HNSCC) cells, and on a mice model of xenograft tumor growth/cell pr
Autor:
Gilberto L. Pardo-Andreu, Javier Marín-Prida, Michael Gonzalez, Luciane C. Alberici, Yamila Verdecia-Reyes, Estael Ochoa-Rodríguez, Roberto Fernández-Acosta
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO3-7
Autor:
Jeney Ramírez-Sánchez, René Delgado-Hernández, Yeniceis Alcantara Issac, Estael Ochoa-Rodríguez, Diogo O. Souza, Gilberto L. Pardo Andreu, Yamila Verdecia-Reyes, Yanier Nuñez-Figueredo
Publikováno v:
Drug Research. 68:263-269
Free radicals are important mediators in a number of neurodegenerative diseases and molecules capable of scavenging reactive oxygen species (ROS) may be a feasible strategy for protecting neuronal cells. In this sense, polyphenols have been studied f