Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yamato Sano"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study was aimed to evaluate whether the dose–response relationship of the sodium glucose co-transporter-2 inhibitors (SGLT2is) in patients with type 2 diabetes mellitus (T2DM)—canagliflozin, dapagliflozin, empagliflozin, ipraglifloz
Externí odkaz:
https://doaj.org/article/c8f7851be87649e49f1166c1f49d57a8
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 48:257-269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5bf0e99ac883c753acf31c90ce4d33b
https://doi.org/10.1007/s13318-023-00818-8
https://doi.org/10.1007/s13318-023-00818-8
Autor:
Hiroaki Norimoto, Noriko Matsukawa, Hiroto Kojima, Yuki Miura, Hiroto Mizuta, Yuji Ikegaya, Hiroyuki Kusuhara, Fumitaka Masuda, Daisuke Nakayama, Aoi Ashizuka, Naoki Yamauchi, Hiroshi Nomura, Yamato Sano, Zohal Baraki, Ayame Kubo, Natsuko Hitora-Imamura, Ryoki Saito, Ken Orita, Masabumi Minami, Tomoe Ishikawa, Mami Okada, Hidehiko Takahashi
Publikováno v:
Biological psychiatry. 86(3):230-239
Background A method that promotes the retrieval of lost long-term memories has not been well established. Histamine in the central nervous system is implicated in learning and memory, and treatment with antihistamines impairs learning and memory. Bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0708b761db14672ecdef1230851834d3
http://hdl.handle.net/2115/79001
http://hdl.handle.net/2115/79001
Autor:
Hiroyuki Kusuhara, Yamato Sano, Yasuaki Einaga, Hiroshi Hibino, Seishiro Sawamura, Genki Ogata, Madoka Takai, Kai Asai
Publikováno v:
Folia Pharmacologica Japonica. 153:273-277
Continuous and real-time measurement of local concentrations of systemically administered drugs in vivo must be crucial for pharmacological studies. Nevertheless, conventional methods require considerable samples quantity and have poor sampling rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4374ef769884834174ec6b8437e5b430
https://doi.org/10.1254/fpj.153.273
https://doi.org/10.1254/fpj.153.273
Autor:
Hiroyuki Kusuhara, Hiroshi Hibino, Yamato Sano, Madoka Takai, Yasuaki Einaga, Genki Ogata, Kai Asai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO2-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc432b01a90e57ce30367f02a99c080c
https://doi.org/10.1254/jpssuppl.wcp2018.0_po2-14-14
https://doi.org/10.1254/jpssuppl.wcp2018.0_po2-14-14
Autor:
Seishiro Sawamura, Yasuaki Einaga, Yuya Ishii, Kazuya Maeda, Takamasa Yoshida, Takeru Ota, Ian Findlay, Hiroyuki Kusuhara, Karin Hori, Katsumi Doi, Hiroshi Hibino, Fumiaki Nin, Madoka Takai, Shizuo Komune, Yamato Sano, Genki Ogata, Taiga Higuchi, Kai Asai
Publikováno v:
Nature Biomedical Engineering
Nature Biomedical Engineering, Nature Publishing Group, 2017, 1 (8), pp.654-666. ⟨10.1038/s41551-017-0118-5⟩
Nature Biomedical Engineering, Nature Publishing Group, 2017, 1 (8), pp.654-666. ⟨10.1038/s41551-017-0118-5⟩
Real-time recording of the kinetics of systemically administered drugs in in vivo microenvironments may accelerate the development of effective medical therapies. However, conventional methods require considerable analyte quantities, have low samplin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65eb023cb056d0a8361a77463adab78
https://doi.org/10.1038/s41551-017-0118-5
https://doi.org/10.1038/s41551-017-0118-5
Autor:
Kazuya Maeda, Yuri Tsuruya, Koji Kato, Yuji Kumagai, Hiroyuki Kusuhara, Yuichi Sugiyama, Yuichiro Imamura, Yamato Sano
Publikováno v:
Drug Metabolism and Disposition. 44:1925-1933
This study was a comprehensive analysis of metabolites in plasma and urine specimens from subjects who received probenecid, a potent inhibitor of renal organic anion transporters (OATs). Taurine and glycochenodeoxycholate sulfate (GCDCA-S) could be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a3a2f05906c65dd43c76e44c28cec
https://doi.org/10.1124/dmd.116.071472
https://doi.org/10.1124/dmd.116.071472
Autor:
Tetsuya Terasaki, Tatsuki Mochizuki, Mina Umetsu, Yasuno Uchida, Hiroyuki Kusuhara, Tadahaya Mizuno, Yamato Sano
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 46(11)
The present study aimed to establish a humanized mouse model with which to explore OATP1A2-mediated transcellular transport of drug substrates across the blood-brain barrier (BBB) and to evaluate the usefulness of the humanized mice in preclinical st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404424c1fb7046f7a20c1c7bf079070f
https://pubmed.ncbi.nlm.nih.gov/30154106
https://pubmed.ncbi.nlm.nih.gov/30154106
Autor:
Madoka Takai, Genki Ogata, Hiroyuki Kusuhara, Yasuaki Einaga, Kai Asai, Yamato Sano, Hiroshi Hibino, Seishiro Sawamura
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2-S14
Continuous and real-time measurement of local concentrations of systemically administered drugs in vivo must be crucial for pharmacological studies. Nevertheless, conventional methods require considerable samples quantity and have poor sampling rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b83dabd83673c00ee483b9849e7c893
https://doi.org/10.1254/jpssuppl.92.0_2-s14-4
https://doi.org/10.1254/jpssuppl.92.0_2-s14-4