Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yamanappa, Hunashal"'
Autor:
Yamanappa Hunashal, Ganesan Senthil Kumar, Meng S. Choy, Éverton D. D’Andréa, Andre Da Silva Santiago, Marta V. Schoenle, Charlene Desbonnet, Michel Arthur, Louis B. Rice, Rebecca Page, Wolfgang Peti
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Penicillin-binding proteins (PBPs) are essential for the formation of the bacterial cell wall. They are also the targets of β-lactam antibiotics. In Enterococcus faecium, high levels of resistance to β-lactams are associated with the expre
Externí odkaz:
https://doaj.org/article/efe2618fd88b4d73a831c3e68a302e4f
Autor:
Gennaro Esposito, Yamanappa Hunashal, Mathias Percipalle, Federico Fogolari, Tomas Venit, Ainars Leonchiks, Kristin C Gunsalus, Fabio Piano, Piergiorgio Percipalle
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303839 (2024)
The interaction between SARS-CoV-2 non-structural protein Nsp9 and the nanobody 2NSP90 was investigated by NMR spectroscopy using the paramagnetic perturbation methodology PENELOP (Paramagnetic Equilibrium vs Nonequilibrium magnetization Enhancement
Externí odkaz:
https://doaj.org/article/a0e1d5066c4b437da54641185d876771
Autor:
L. Palanikumar, Laura Karpauskaite, Mohamed Al-Sayegh, Ibrahim Chehade, Maheen Alam, Sarah Hassan, Debabrata Maity, Liaqat Ali, Mona Kalmouni, Yamanappa Hunashal, Jemil Ahmed, Tatiana Houhou, Shake Karapetyan, Zackary Falls, Ram Samudrala, Renu Pasricha, Gennaro Esposito, Ahmed J. Afzal, Andrew D. Hamilton, Sunil Kumar, Mazin Magzoub
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Amyloid aggregation of mutant p53 contributes to its loss of tumor suppressor function and oncogenic gain-of-function. Here, the authors use a protein mimetic to abrogate mutant p53 aggregation and rescue p53 function, which inhibits cancer cell prol
Externí odkaz:
https://doaj.org/article/aabfbc8d47544f739652c54bd2eb3f1f
Publikováno v:
Molecules, Vol 26, Iss 12, p 3567 (2021)
Background: Nanobodies, or VHHs, are derived from heavy chain-only antibodies (hcAbs) found in camelids. They overcome some of the inherent limitations of monoclonal antibodies (mAbs) and derivatives thereof, due to their smaller molecular size and h
Externí odkaz:
https://doaj.org/article/3a448972d2c1403ab2a2f3e9d28701aa
Autor:
Yamanappa Hunashal, Cristina Cantarutti, Sofia Giorgetti, Loredana Marchese, Federico Fogolari, Gennaro Esposito
Publikováno v:
Molecules, Vol 25, Iss 21, p 5187 (2020)
Background: The interaction between proteins and nanoparticles is a very relevant subject because of the potential applications in medicine and material science in general. Further interest derives from the amyloidogenic character of the considered p
Externí odkaz:
https://doaj.org/article/c07d3cc2588348b3af1c2ab9b838e43d
Autor:
Laura Karpauskaite, Ahmed J. Afzal, Ibrahim Chehade, Jemil Ahmed, Renu Pasricha, Mazin Magzoub, Andrew D. Hamilton, Debabrata Maity, Mona Kalmouni, Loganathan Palanikumar, Sunil Kumar, Maheen Alam, Tatiana Houhou, Gennaro Esposito, Zackary Falls, Shake Karapetyan, Yamanappa Hunashal, Ram Samudrala, Mohamed Al-Sayegh, Liaqat Ali, Sarah Hassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-24 (2021)
Nature Communications
Nature Communications
Missense mutations in p53 are severely deleterious and occur in over 50% of all human cancers. The majority of these mutations are located in the inherently unstable DNA-binding domain (DBD), many of which destabilize the domain further and expose it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914b9d23167b4db0a4609f8d776a3030
https://doaj.org/article/aabfbc8d47544f739652c54bd2eb3f1f
https://doaj.org/article/aabfbc8d47544f739652c54bd2eb3f1f
Autor:
Miguel Angel Soler, Ozge Ozkilinc, Yamanappa Hunashal, Paolo Giannozzi, Gennaro Esposito, Federico Fogolari
Publikováno v:
Computer Physics Communications. 287:108716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd770c867c214fa23326fdc75feb4cc
https://doi.org/10.1016/j.cpc.2023.108716
https://doi.org/10.1016/j.cpc.2023.108716
Autor:
Himansu S. Biswal, Shamasoddin Shekh, Sunita Prakash, Marimuthu Vijayasarathy, Srinivasarao Raghothama, Ashwini Dolle, Yamanappa Hunashal, K. Kasi Amarnath Reddy, Konkallu Hanumae Gowd, Abhijit Rana
Publikováno v:
Biochemistry. 60:1299-1311
The tetrapeptides Li504 and Li520, differing in the modification of the 4-trans-hydroxylation of proline, are novel conopeptides derived from the venom duct transcriptome of the marine cone snail Conus lividus. These predicted mature peptides are hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ab871984963e576c9fcf847d1300a97
https://doi.org/10.1021/acs.biochem.1c00090
https://doi.org/10.1021/acs.biochem.1c00090
Autor:
Yamanappa Hunashal, Mathias Percipalle, Tamás Molnár, Jòzsef Kardos, Piergiorgio Percipalle, Gennaro Esposito
Publikováno v:
Analytical chemistry. 94(31)
PENELOP (Paramagnetic Equilibrium vs Nonequilibrium magnetization Enhancement or LOss Perturbation) is the presented nuclear magnetic resonance (NMR) approach to identify at once the location of proteins' exposed surface, hindered accessibility, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98735cc9a35c9cd89ee65ad1a276bcf0
https://pubmed.ncbi.nlm.nih.gov/35877130
https://pubmed.ncbi.nlm.nih.gov/35877130
Autor:
Reyad S. Obaid, Fathalla Hamed, Yamanappa Hunashal, Hassan Abdullah, Emmanuel Galiwango, Gennaro Esposito, Basim Abu-Jdayil, Camila Tamiello-Rosa, Mutamed M. Ayyash, Pariyaporn Itsaranuwat
Publikováno v:
International Journal of Biological Macromolecules. 144:938-946
Various industries highly regard the functionalities and bioactivities of bacterial polysaccharides. We aimed to characterize the exopolysaccharide (EPS) produced by novel probiotic Lactobacillus plantarum C70 (accession number KX881779) isolated fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e79c71adbb54daa61390654def8d7d
https://doi.org/10.1016/j.ijbiomac.2019.09.171
https://doi.org/10.1016/j.ijbiomac.2019.09.171