Synthesis of C12‐Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage‐Gated Sodium Channels.

Autor: Adachi, Kanna¹ (AUTHOR), Yamada, Tomoshi² (AUTHOR), Ishizuka, Hayate¹ (AUTHOR), Oki, Mana¹ (AUTHOR), Tsunogae, Shunsuke² (AUTHOR), Shimada, Noriko² (AUTHOR), Chiba, Osamu² (AUTHOR), Orihara, Tatsuya¹ (AUTHOR), Hidaka, Masafumi² (AUTHOR), Hirokawa, Takatsugu^3,4,5 (AUTHOR), Odagi, Minami¹ (AUTHOR), Konoki, Keiichi² (AUTHOR) keiichi.konoki.b2@tohoku.ac.jp, Yotsu‐Yamashita, Mari² (AUTHOR) mari.yamashita.c1@tohoku.ac.jp, Nagasawa, Kazuo¹ (AUTHOR) knaga@cc.tuat.ac.jp

Publikováno v: Chemistry - A European Journal. 2/11/2020, Vol. 26 Issue 9, p2025-2033. 9p.

Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Nav 1.1 to Nav 1.7).

Autor: Tsukamoto, Tadaaki, Chiba, Yukie, Wakamori, Minoru, Yamada, Tomoshi, Tsunogae, Shunsuke, Cho, Yuko, Sakakibara, Ryo, Imazu, Takuya, Tokoro, Shouta, Satake, Yoshiki, Adachi, Masaatsu, Nishikawa, Toshio, Yotsu ‐ Yamashita, Mari, Konoki, Keiichi, Yotsu-Yamashita, Mari

Publikováno v: British Journal of Pharmacology; Nov2017, Vol. 174 Issue 21, p3881-3892, 12p