Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yama W L Zheng"'
Autor:
Daan van Abel, Dennis R Hölzel, Shushant Jain, Fiona M F Lun, Yama W L Zheng, Eric Z Chen, Hao Sun, Rossa W K Chiu, Y M Dennis Lo, Marie van Dijk, Cees B M Oudejans
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21994 (2011)
BackgroundIn this study, we performed a genome-wide search for effector genes bound by STOX1A, a winged helix transcription factor recently demonstrated to be involved in late onset Alzheimer's disease and affecting the amyloid processing pathway.Met
Externí odkaz:
https://doaj.org/article/f1ff01424925411ea32e35d5eec9667e
Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing.
Autor:
Eric Z Chen, Rossa W K Chiu, Hao Sun, Ranjit Akolekar, K C Allen Chan, Tak Y Leung, Peiyong Jiang, Yama W L Zheng, Fiona M F Lun, Lisa Y S Chan, Yongjie Jin, Attie T J I Go, Elizabeth T Lau, William W K To, Wing C Leung, Rebecca Y K Tang, Sidney K C Au-Yeung, Helena Lam, Yu Y Kung, Xiuqing Zhang, John M G van Vugt, Ryoko Minekawa, Mary H Y Tang, Jun Wang, Cees B M Oudejans, Tze K Lau, Kypros H Nicolaides, Y M Dennis Lo
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21791 (2011)
Massively parallel sequencing of DNA molecules in the plasma of pregnant women has been shown to allow accurate and noninvasive prenatal detection of fetal trisomy 21. However, whether the sequencing approach is as accurate for the noninvasive prenat
Externí odkaz:
https://doaj.org/article/79bcfe2a4cb842b498a88221fab38ddf
Autor:
Yama W. L. Zheng, Shing Shun N. Siu, Stephen L. Chan, Rossa W.K. Chiu, Wing Cheong Chan, Yuk Ming Dennis Lo, John Wong, Paul B.S. Lai, K.C. Allen Chan, Peiyong Jiang, Gary J. W. Liao, Hao Sun, Anthony T.C. Chan
Publikováno v:
Clinical Chemistry. 59:211-224
BACKGROUND Tumor-derived DNA can be found in the plasma of cancer patients. In this study, we explored the use of shotgun massively parallel sequencing (MPS) of plasma DNA from cancer patients to scan a cancer genome noninvasively. METHODS Four hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075f5b258aae065b6eacbfa1513ef2ae
https://doi.org/10.1373/clinchem.2012.196014
https://doi.org/10.1373/clinchem.2012.196014
Autor:
Peiyong Jiang, Hao Sun, Yuk Ming Dennis Lo, Gary J. W. Liao, Tak Yeung Leung, Rossa W.K. Chiu, Yama W. L. Zheng, K.C. Allen Chan
Publikováno v:
Bioinformatics. 28:2883-2890
Motivation: The fractional fetal DNA concentration is one of the critical parameters for non-invasive prenatal diagnosis based on the analysis of DNA in maternal plasma. Massively parallel sequencing (MPS) of DNA in maternal plasma has been demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ec271687aa2027f350278a35828c69
https://doi.org/10.1093/bioinformatics/bts549
https://doi.org/10.1093/bioinformatics/bts549
Autor:
Attie T. J. I. Go, Gary J. W. Liao, Stephanie C.Y. Yu, Yama W. L. Zheng, Y.M. Dennis Lo, Rossa W.K. Chiu, K.C. Allen Chan, Kypros H. Nicolaides, Peiyong Jiang, Ranjit Akolekar, Hao Sun, Ryoko Minekawa, John M. G. van Vugt, Cees B.M. Oudejans, Tak Yeung Leung
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 111(23), 8583-8588. National Academy of Sciences
Yu, S C, Chan, K, Zheng, Y W, Jiang, P, Liao, G J, Sun, H, Akolekar, R, Leung, T Y, Go, A T, van Vugt, J M, Minekawa, R, Oudejans, C B M, Nicolaides, K H, Chiu, R W & Lo, Y 2014, ' Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing ', Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 23, pp. 8583-8588 . https://doi.org/10.1073/pnas.1406103111
Proceedings of the National Academy of Sciences USA, 111, 23, pp. 8583-8
Proceedings of the National Academy of Sciences USA, 111, 8583-8
Yu, S C, Chan, K, Zheng, Y W, Jiang, P, Liao, G J, Sun, H, Akolekar, R, Leung, T Y, Go, A T, van Vugt, J M, Minekawa, R, Oudejans, C B M, Nicolaides, K H, Chiu, R W & Lo, Y 2014, ' Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing ', Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 23, pp. 8583-8588 . https://doi.org/10.1073/pnas.1406103111
Proceedings of the National Academy of Sciences USA, 111, 23, pp. 8583-8
Proceedings of the National Academy of Sciences USA, 111, 8583-8
Item does not contain fulltext Noninvasive prenatal testing using fetal DNA in maternal plasma is an actively researched area. The current generation of tests using massively parallel sequencing is based on counting plasma DNA sequences originating f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2655d724384234cb0181f4848a6a823f
https://research.vumc.nl/en/publications/b619e2fa-5db3-4912-99b5-6b0d23f8465e
https://research.vumc.nl/en/publications/b619e2fa-5db3-4912-99b5-6b0d23f8465e
Autor:
Hao Sun, Xiaoxi Su, Eric Z. Chen, Yama W. L. Zheng, John Wong, K.C. Allen Chan, Peiyong Jiang, Emily C.W. Hung, Vincent Lee, Fiona M.F. Lun, Y.M. Dennis Lo, Paul B.S. Lai, Chi Kong Li, Rossa W.K. Chiu
Publikováno v:
Clinical chemistry. 58(3)
BACKGROUND Plasma DNA is predominantly hematopoietic in origin. The size difference between maternal- and fetal-derived DNA in maternal plasma prompted us to investigate whether there was any discrepancy in molecular size between hematopoietically an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd2cefea94929dae3f7416e129cedd1
https://pubmed.ncbi.nlm.nih.gov/22235102
https://pubmed.ncbi.nlm.nih.gov/22235102
Autor:
Cees B.M. Oudejans, Rossa W.K. Chiu, Marie van Dijk, Yama W. L. Zheng, Eric Z. Chen, Dennis R. Hölzel, Daan van Abel, Shushant Jain, Fiona M.F. Lun, Hao Sun, Y.M. Dennis Lo
Publikováno v:
PLoS ONE
PLoS ONE, 6(7):e21994. Public Library of Science
van Abel, D, Holzel, D R, Jain, S, Lun, F M F, Zheng, Y M W L, Chen, E Z, Sun, H, Chiu, R W K, Lo, Y M D, van Dijk, M & Oudejans, C B M 2011, ' SFRS7-Mediated Splicing of Tau Exon 10 Is Directly Regulated by STOX1A in Glial Cells ', PLoS ONE, vol. 6, no. 7, e21994 . https://doi.org/10.1371/journal.pone.0021994
PLoS ONE, Vol 6, Iss 7, p e21994 (2011)
PLoS ONE, 6(7):e21994. Public Library of Science
van Abel, D, Holzel, D R, Jain, S, Lun, F M F, Zheng, Y M W L, Chen, E Z, Sun, H, Chiu, R W K, Lo, Y M D, van Dijk, M & Oudejans, C B M 2011, ' SFRS7-Mediated Splicing of Tau Exon 10 Is Directly Regulated by STOX1A in Glial Cells ', PLoS ONE, vol. 6, no. 7, e21994 . https://doi.org/10.1371/journal.pone.0021994
PLoS ONE, Vol 6, Iss 7, p e21994 (2011)
BackgroundIn this study, we performed a genome-wide search for effector genes bound by STOX1A, a winged helix transcription factor recently demonstrated to be involved in late onset Alzheimer's disease and affecting the amyloid processing pathway.Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54288e77980c5789ec0bba99681913b8
http://europepmc.org/articles/PMC3130792
http://europepmc.org/articles/PMC3130792
Autor:
Sidney K. C. Au-Yeung, Ranjit Akolekar, Ryoko Minekawa, Kypros H. Nicolaides, Yu Y. Kung, Yama W. L. Zheng, Cees B.M. Oudejans, Mary Hoi Yin Tang, Attie T. J. I. Go, John M. G. van Vugt, Rebecca Y. K. Tang, Fiona M.F. Lun, K.C. Allen Chan, Lisa Y.S. Chan, Eric Z. Chen, Peiyong Jiang, Tak Yeung Leung, Rossa W.K. Chiu, Xiuqing Zhang, Y.M. Dennis Lo, Hao Sun, W. C. Leung, William W. K. To, H. Lam, Yongjie Jin, Tze K. Lau, Jun Wang, Elizabeth T. Lau
Publikováno v:
Chen, E Z, Chiu, R W K, Sun, H, Akolekar, R, Chan, K C A, Leung, T Y, Jiang, P Y, Zheng, Y W L, Lun, F M F, Chan, L Y S, Jin, Y J, Go, A T J I, Lau, E T, To, W W K, Leung, W C, Tang, R Y K, Au-Yeung, S K C, Lam, H, Kung, Y Y, Zhang, X Q, van Vugt, J M G, Minekawa, R, Tang, M H Y, Wang, J, Oudejans, C B M, Lau, T K, Nicolaides, K H & Lo, Y M D 2011, ' Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing ', PLoS ONE, vol. 6, no. 7, e21791 . https://doi.org/10.1371/journal.pone.0021791
PLoS ONE
PLoS ONE, 6(7):e21791. Public Library of Science
PLoS One, 6
PLoS ONE, Vol 6, Iss 7, p e21791 (2011)
PLoS One, 6, 7
PLoS ONE
PLoS ONE, 6(7):e21791. Public Library of Science
PLoS One, 6
PLoS ONE, Vol 6, Iss 7, p e21791 (2011)
PLoS One, 6, 7
Massively parallel sequencing of DNA molecules in the plasma of pregnant women has been shown to allow accurate and noninvasive prenatal detection of fetal trisomy 21. However, whether the sequencing approach is as accurate for the noninvasive prenat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1367bab05a0af2574c128e9c13e8c412
https://research.vumc.nl/ws/files/866060/282572.pdf
https://research.vumc.nl/ws/files/866060/282572.pdf
Autor:
K.C. Allen Chan, Yama W. L. Zheng, Rossa W.K. Chiu, Fiona M.F. Lun, Y.M. Dennis Lo, Tak Yeung Leung, Gary J. W. Liao, Tze K. Lau
Publikováno v:
Clinical chemistry. 57(1)
BACKGROUND Massively parallel sequencing has recently been used in noninvasive prenatal diagnosis. The current costs of this technology are still relatively expensive, however, and sample throughput is still relatively low when it is used as a molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7e87006dd1dcb75cc0610a1b0cb69b
https://pubmed.ncbi.nlm.nih.gov/21078840
https://pubmed.ncbi.nlm.nih.gov/21078840
Autor:
Hao Sun, Sidney K. C. Au-Yeung, Rebecca Y. K. Tang, Ryoko Minekawa, Attie T. J. I. Go, William W. K. To, Yu Y. Kung, Mary Hoi Yin Tang, Fiona M.F. Lun, Y.M. Dennis Lo, W. C. Leung, Ranjit Akolekar, Rossa W.K. Chiu, Kypros H. Nicolaides, Tze K. Lau, Elizabeth T. Lau, Cees B.M. Oudejans, John M.G. van Vugt, Yama W. L. Zheng, Jun Wang, H. Lam, K.C. Allen Chan, Tak Yeung Leung, Xiuqing Zhang
Publikováno v:
The BMJ
Chiu, R W K, Akolekar, R, Zheng, Y W L, Leung, T Y, Sun, H, Chan, K C A, Lun, F M F, Go, A T J I, Lau, E T, To, W W K, Leung, W C, Tang, R Y K, Au-Yeung, S K C, Lam, H, Kung, Y Y, Zhang, X Q, van Vugt, J M G, Minekawa, R, Tang, M H Y, Wang, J, Oudejans, C B M, Lau, T K, Nicolaides, K H & Lo, Y M D 2011, ' Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study ', British Medical Journal, vol. 342, pp. c7401 . https://doi.org/10.1136/bmj.c7401
Bmj. British Medical Journal (Compact Ed.), 342, pp. c7401-c7401
Bmj. British Medical Journal (Compact Ed.), 342, c7401-c7401
British Medical Journal, 342
Chiu, R W K, Akolekar, R, Zheng, Y W L, Leung, T Y, Sun, H, Chan, K C A, Lun, F M F, Go, A T J I, Lau, E T, To, W W K, Leung, W C, Tang, R Y K, Au-Yeung, S K C, Lam, H, Kung, Y Y, Zhang, X Q, van Vugt, J M G, Minekawa, R, Tang, M H Y, Wang, J, Oudejans, C B M, Lau, T K, Nicolaides, K H & Lo, Y M D 2011, ' Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study ', British Medical Journal, vol. 342, pp. c7401 . https://doi.org/10.1136/bmj.c7401
Bmj. British Medical Journal (Compact Ed.), 342, pp. c7401-c7401
Bmj. British Medical Journal (Compact Ed.), 342, c7401-c7401
British Medical Journal, 342
Objectives To validate the clinical efficacy and practical feasibility of massively parallel maternal plasma DNA sequencing to screen for fetal trisomy 21 among high risk pregnancies clinically indicated for amniocentesis or chorionic villus sampling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6e06751b9bf28bfdb926a1aa39dcd4
https://hdl.handle.net/2066/97164
https://hdl.handle.net/2066/97164