Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yaling Qiu"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73542 (2013)
GFI1 is a transcriptional repressor that plays a critical role in hematopoiesis and has also been implicated in lymphomagenesis. It is still poorly understood how GFI1 expression is regulated in the hematopoietic system. We show here that GFI1 transc
Externí odkaz:
https://doaj.org/article/895bcd26b2d8439d911bc0fef1b42999
Publikováno v:
Biomarkers in medicine.
Purpose: To investigate the role of serum CYR61 as a biomarker for the diagnosis of breast cancer and to analyze the association between serum CYR61 levels and the clinicopathological features in breast cancer patients. Methods: Serum CYR61 was measu
Mutations in ELANE encoding neutrophil elastase (NE) have been identified in the majority of patients with severe congenital neutropenia (SCN). The NE mutants have been shown to activate unfolded protein response and induce premature apoptosis in mye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e245edafffc068a5c0c02e3f27bc9a77
https://europepmc.org/articles/PMC5336180/
https://europepmc.org/articles/PMC5336180/
Publikováno v:
Oncogene
Zinc-finger (ZF) transcriptional repressor growth factor independence 1 (Gfi-1) has an important role in hematopoiesis and inner ear development, and also functions as an oncoprotein that cooperates with c-Myc in lymphomagenesis. Gfi-1 represses tran
Publikováno v:
The Journal of biological chemistry. 290(40)
Lineage specification in the hematopoietic system depends on the expression of lineage specific transcription factors. However, the role of hematopoietic cytokines in this process has been controversial and little is known about the intracellular sig
Publikováno v:
Journal of Biological Chemistry. 281:10745-10751
Granulocyte-colony-stimulating factor (G-CSF) stimulates the activation of multiple signaling pathways, leading to alterations in the activities of transcription factors. Gfi-1 is a zinc finger transcriptional repressor that is required for granulopo
Publikováno v:
Leukemia Research. 29:1153-1162
Granulocyte colony-stimulating factor (G-CSF) has been shown to stimulate the activation of the signal transducer and activator of transcription 5 (Stat5). We show here that G-CSF-stimulated activation of Stat5 was attenuated when myeloid cells were
Publikováno v:
The Journal of Immunology. 167:6447-6452
The G-CSF receptor transduces signals that regulate the proliferation, differentiation, and survival of myeloid cells. A subgroup of patients with severe congenital neutropenia (SCN) has been shown to harbor mutations in the G-CSF receptor gene that
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73542 (2013)
PLoS ONE, Vol 8, Iss 9, p e73542 (2013)
Abstract 1228 Gfi1 is a transcriptional repressor that plays a critical role in hematopoiesis. Gfi1 has also been implicated in lymphomagenesis when aberrantly activated as a result of deregulated expression. It is still poorly understood how Gfi1 ex
Gfi-1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. Gfi-1 represses transcription by directly binding to the consensus DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980dbcf0c6695a67b76f7afa342b6408
https://europepmc.org/articles/PMC2635772/
https://europepmc.org/articles/PMC2635772/