Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yaling Gan"'
Autor:
Yongchao Wang, Ningqiang Gong, Chi Ma, Yuxuan Zhang, Hong Tan, Guangchao Qing, Jimei Zhang, Yufei Wang, Jinjin Wang, Shizhu Chen, Xianlei Li, Qiankun Ni, Yuan Yuan, Yaling Gan, Junge Chen, Fangzhou Li, Jinchao Zhang, Caiwen Ou, Yongxiang Zhao, Xiaoxuan Liu, Xing-Jie Liang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Immunological adjuvants are a crucial component of cancer vaccines. Here the authors design a light-activable immunological adjuvant, based on hypoxia-responsive amphiphilic dendrimer nanoparticles loaded with a photodynamic agent, promoting anti-tum
Externí odkaz:
https://doaj.org/article/9406f8b05e734a97845b344a34803f0b
Autor:
Guangchao Qing, Xianxian Zhao, Ningqiang Gong, Jing Chen, Xianlei Li, Yaling Gan, Yongchao Wang, Zhen Zhang, Yuxuan Zhang, Weisheng Guo, Yang Luo, Xing-Jie Liang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Antibiotic resistance is a major global health challenge. Here, the authors report on a thermoresponsive delivery system for combined photothermal and antibiotic delivery with fluorescent tracking abilities and demonstrate application against antibio
Externí odkaz:
https://doaj.org/article/e07913e02ed249c4b04fd42124a95546
Publikováno v:
The Innovation, Vol 1, Iss 3, Pp 100057- (2020)
Recent progress at the National Center for Nanoscience and Technology of China has enabled an extremely facile method to encapsulate irinotecan (CPT-11) into micelle-based nanoparticles (named as IH-NM). In preclinical study, compared with free CPT-1
Externí odkaz:
https://doaj.org/article/2089af690f3346f8b2bce5e69609fb49
Autor:
Yanan Jin, Juanjuan Jia, Chan Li, Jianqi Xue, Jiabei Sun, Kaiyuan Wang, Yaling Gan, Jing Xu, Yaqin Shi, Xingjie Liang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 13, Iss 3, Pp 289-296 (2018)
Endotoxin detection is an important step in drug characterization. Herein we found that a chemotherapeutic drug nanoformulation composed of irinotecan hydrochloride (CPT-11) and an amphiphilic molecule DSPE-mPEG2000 can interfere with the limulus ame
Externí odkaz:
https://doaj.org/article/a419ec5f85074deb9771d1761c02f0fa
Autor:
Hui-li Ma, Qiao Jiang, Siyuan Han, Yan Wu, Jin Cui Tomshine, Dongliang Wang, Yaling Gan, Guozhang Zou, Xing-Jie Liang
Publikováno v:
Molecular Imaging, Vol 11 (2012)
We present a flexible and highly reproducible method using three-dimensional (3D) multicellular tumor spheroids to quantify chemotherapeutic and nanoparticle penetration properties in vitro. We generated HeLa cell–derived spheroids using the liquid
Externí odkaz:
https://doaj.org/article/4acb0cebf3bc4cb983b88bb0b1d07155
Publikováno v:
Materials Express. 13:337-344
Lactose is an important pharmaceutical excipient in the drug industry. Residual protein in lactose derived from cow milk can cause acute allergic reactions in some patients, especially when lactose-containing drugs are administered via the intravenou
Autor:
Yi-Feng Wang, Qingrong Zhang, Falin Tian, Hongda Wang, Yufei Wang, Xiaowei Ma, Qianqian Huang, Mingjun Cai, Yinglu Ji, Xiaochun Wu, Yaling Gan, Yan Yan, Kenneth A. Dawson, Shutao Guo, Jinchao Zhang, Xinghua Shi, Yuping Shan, Xing-Jie Liang
Publikováno v:
ACS nano. 16(3)
Endocytosis, as one of the main ways for nanostructures enter cells, is affected by several aspects, and shape is an especially critical aspect during the endocytosis of nanostructures. However, it has remained challenging to capture the dynamic inte
Autor:
Tingbin Zhang, Xiao’ai Chen, Jie Yu, Ningqiang Gong, Huaidong Jiang, Xing-Jie Liang, Xucong Teng, Xiaowei Ma, Yaling Gan, Shengkun Yao, Xiaoli Tan, Xixue Hu, Shuaidong Huo, Qunfang Zhou, Shizhu Chen, Xiaoxia Ye, Jinghong Li
Publikováno v:
Nature Nanotechnology. 14:379-387
Mitochondrial redox homeostasis, the balance between reactive oxygen species and antioxidants such as glutathione, plays critical roles in many biological processes, including biosynthesis and apoptosis, and thus is a potential target for cancer trea
Autor:
Jinchao Zhang, Yaling Gan, Yongxiang Zhao, Hong Tan, Ningqiang Gong, Xianlei Li, Chi Ma, Shizhu Chen, Yufei Wang, Zhang Jimei, Xing-Jie Liang, Fangzhou Li, Qiankun Ni, Yongchao Wang, Caiwen Ou, Jinjin Wang, Yuxuan Zhang, Yuan Yuan, Junge Chen, Xiaoxuan Liu, Guangchao Qing
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Immunological adjuvants are essential for successful cancer vaccination. However, traditional adjuvants have some limitations, such as lack of controllability and induction of systemic toxicity, which restrict their broad application. Here, we presen
Autor:
Paul C. Wang, Jinchao Zhang, Qiankun Ni, Xianlei Li, Shizhu Chen, Yaling Gan, Xing-Jie Liang, Ningqiang Gong, Michael J. Mitchell, Yongchao Wang, Yongji Wang, Xiaoxia Ye, Shuaidong Huo, Jinghong Li, Jie Yu, Tingbin Zhang, Xucong Teng, Jinjin Wang, Yuxuan Zhang, Guangchao Qing
Publikováno v:
Nat Nanotechnol
Cancer vaccines hold great promise for improved cancer treatment. However, endosomal trapping and low immunogenicity of tumour antigens usually limit the efficiency of vaccination strategies. Here, we present a proton-driven nanotransformer-based vac