Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Yale B Mitchel"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 12, Pp 2641-2647 (2008)
This analysis evaluates the effects on lipoprotein subfractions and LDL particle size of ezetimibe/simvastatin with or without coadministration of fenofibrate in patients with mixed hyperlipidemia. This multicenter, double-blind, placebo-controlled,
Externí odkaz:
https://doaj.org/article/a0ba5d874ffe475e9f58f04538221fc8
Autor:
Siddharth M Patel, Christopher P Cannon, KyungAh Im, Michael A Blazing, Yale B Mitchel, Marc S Sabatine, Robert P Giugliano, Erin A Bohula
Publikováno v:
Circulation. 144
Introduction: Ezetimibe (EZE) added to statin further reduces LDL-C and CV events. Prior studies demonstrated large inter-individual variability in LDL-C reduction with statins. Whether similar variability exists with EZE has not been reported in a l
Autor:
Yale B. Mitchel, Jennifer A. White, Robert P. Giugliano, Ping He, Eugene Braunwald, Jeong-Gun Park, Michael A. Blazing, Sabina A. Murphy, David A. Morrow, Terje R. Pedersen, Adrian J B Brady, Christopher P. Cannon, Y. Antero Kesäniemi, Erin A. Bohula
Publikováno v:
Journal of the American College of Cardiology. 69:911-921
Background Ezetimibe improves cardiovascular (CV) outcomes in patients stabilized after acute coronary syndrome (ACS) when added to statin therapy. After ACS, patients vary considerably in their risk for recurrent CV events. Objectives This study tes
Autor:
Christopher P. Cannon, Michael A. Blazing, Yuliya Lokhnygina, Ann Marie Navar, Thomas Musliner, Michael G. Nanna, Jennifer A. White, Robert P. Giugliano, Yale B. Mitchel
Publikováno v:
J Am Coll Cardiol
Muscle-related events, including less severe muscle complaints without a clear pharmacological relationship to the treatment, may hamper compliance with lipid-lowering therapy and increase the risk of drug discontinuation ([1][1]). In IMPROVE-IT (Imp
Autor:
J. Fable, Joost Besseling, Yale B. Mitchel, John J.P. Kastelein, A. Sapre, A.O. Johnson-Levonas, S. Shah
Publikováno v:
European Heart Journal. 38
Autor:
Eliot A. Brinton, Antonio M. Gotto, Jennifer Moon, Philip J. Barter, Uma Kher, Sukrut Shah, Manash Shankar Chatterjee, Yang Liu, Christopher P. Cannon, Yale B. Mitchel, Xiujiang Susie Li, Sanskruti Vaidya, Hayes M. Dansky
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 19:543-549
Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has previously been shown to reduce low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C) in patients with or at high risk of coron
Autor:
Sukrut Shah, Ignacio Rodriguez Briones, Tanya B. Ashraf, Yale B. Mitchel, Yugang Dong, Wayne Huey-Heng Sheu, Sandra C. Tobias, Tayfun Sahin, Amy O. Johnson-Levonas, Yulia Moiseeva, P Rossi, Duk-Hyun Kang, Aditi Sapre, Christie M. Ballantyne, Ping Ye
Publikováno v:
The American journal of cardiology. 120(4)
This phase 3, multiregional, randomized, double-blind, placebo-controlled study assessed the efficacy/safety profile of anacetrapib added to ongoing therapy with statin ± other lipid-modifying therapies in patients with hypercholesterolemia who were
Autor:
Alexandra MacLean, Philippe Brudi, Darbie Maccubbin, Joseph Triscari, Erluo Chen, Eliot A. Brinton, Yale B. Mitchel, Amy O. Johnson-Levonas, Christine McCrary Sisk, Rae Ann Ruck
Publikováno v:
Lipids in Health and Disease
Background LDL-C, non-HDL-C and ApoB levels are inter-correlated and all predict risk of atherosclerotic cardiovascular disease (ASCVD) in patients with type 2 diabetes mellitus (T2DM) and/or high TG. These levels are lowered by extended-release niac
Autor:
Anders G. Olsson, Fabian Chen, Christine McCrary Sisk, Waheeda Sirah, Darbie Maccubbin, Yale B. Mitchel, Harold E. Bays, Jennifer W. Anderson, Uma Kher
Publikováno v:
The American Journal of Cardiology. 110:817-822
Extended-release niacin (ERN) improves multiple lipid parameters but is underused owing to niacin-induced flushing (NIF). Laropiprant (LRPT) reduces NIF; however, its effects on chronic flushing (6 months) have not been studied. We examined whether a
Autor:
Nancy Liu, Amy O. Johnson-Levonas, Christine McCrary Sisk, Gilbert W. Gleim, Yale B. Mitchel, Christie M. Ballantyne
Publikováno v:
Journal of Clinical Lipidology. 6:235-243
Background The use of extended-release niacin and the prostaglandin D 2 receptor antagonist laropiprant (ERN/LRPT) reduces niacin-induced flushing in patients while preserving its lipid-modifying effects. Objective This predefined exploratory analysi